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2024 AUG 8 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- According to news reporting based on a preprint abstract, our journalists obtained the following […]

2024 MAY 16 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- In support of Women's Health Week, leading nutrition tracking app, Cronometer, has unlocked their [...]

2024 MAY 9 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- According to news reporting based on a preprint abstract, our journalists obtained the following [...]

2024 APR 18 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- A new study on Menopause is now available. According to news reporting from Durham, [...]

2024 APR 18 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Current study results on osteoporosis have been published. According to news reporting from Birjand, [...]

2024 JAN 25 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Researchers detail new data in hypocalcemia. According to news reporting originating from Ahmadi, Kuwait, [...]

2023 OCT 26 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Researchers detail new data in personalized medicine. According to news reporting out of Haifa, [...]

2023 SEP 28 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Data detailed on Oncology - Breast Cancer have been presented. According to news reporting [...]

2023 JUL 6 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- According to news reporting based on a preprint abstract, our journalists obtained the following [...]

A recent report from Iran University of Medical Sciences explores the effect of vitamin D administration on biochemical factors in patients with polycystic ovary syndrome (PCOS). The study involved 213 women aged 18-40 with PCOS and vitamin D deficiency. The intervention group received metformin and vitamin D, while the control group received only metformin. The results showed that vitamin D supplementation had a positive impact on laboratory indices such as fasting blood sugar, insulin resistance, follicle-stimulating hormone, triglycerides, and high-density lipoprotein. This study suggests that vitamin D may have potential benefits for PCOS patients. [Extracted from the article]

A recent systematic review and meta-analysis conducted by researchers from Kermanshah University of Medical Sciences examined the effect of vitamin D on the hormonal profile of women with polycystic ovarian syndrome (PCOS). PCOS is a common endocrine disorder among women of reproductive age and a leading cause of infertility. The study analyzed 19 articles and found that vitamin D supplementation had a significant positive effect on hormone levels in women with PCOS. The researchers recommend that obstetricians and midwives consider the potential benefits of vitamin D supplementation for women with PCOS. [Extracted from the article]

A recent research study conducted by the Second Affiliated Hospital of Zhejiang University School of Medicine in Hangzhou, China, explored the potential association between vitamin D and gestational diabetes mellitus (GDM). The study utilized a method called Mendelian randomization (MR) with two samples to investigate causality. The results showed a weak negative causal connection between 25-hydroxyvitamin D (25(OH)D) and GDM risk, but this association was unstable and disappeared when BMI-related variables were removed. Additionally, there was little evidence to support a causal link between vitamin D binding protein (VDBP) and GDM. The study suggests that further research is needed to explore the relationship between different forms of vitamin D and GDM in diverse populations. [Extracted from the article]

A study conducted by researchers at Semnan University of Medical Sciences in Iran aimed to determine the effect of vitamin D administration on the clinical and laboratory symptoms of adolescents with polycystic ovary syndrome (PCOS) and vitamin D deficiency. The study involved 50 patients with sonographic evidence of PCOS and vitamin D deficiency, who were divided into control and intervention groups. The intervention group received vitamin D while the control group received a placebo. The results showed that vitamin D administration improved the level of vitamin D in the intervention group and led to significant improvements in fasting insulin level, serum testosterone level, LH to FSH ratio, LH level, diastolic blood pressure, and severity of hirsutism. The study suggests that vitamin D supplementation may help improve the symptoms of PCOS and correct menstrual disorders and hyperandrogenism. However, it did not significantly affect insulin resistance. [Extracted from the article]

A recent study conducted at the Mayo Clinic in Rochester, Minnesota, examined the levels of vitamin D in breastmilk and its potential impact on infant bone development. The study found that concentrations of vitamin D in breastmilk were low, despite its importance for infant bone health. The researchers also investigated the presence of sulfated vitamin D metabolites in breastmilk and serum and found that these metabolites may play a significant role in lactating women and their nursing infants. The study suggests that further research is needed to understand the physiological relevance of these metabolites during lactation. [Extracted from the article]

A recent study conducted by the Servicio de Traumatologia has examined the effectiveness and safety of a combination treatment for vitamin D deficiency. The study involved 302 adult patients who received calcium and cholecalciferol tablets daily for 24 weeks. The results showed that 94.4% of patients experienced an increase in vitamin D levels, with no significant changes in other bone metabolism parameters. The study concluded that this treatment is effective and safe, particularly for patients with osteoporosis. The findings suggest that the severity of vitamin D deficiency affects the magnitude of the increase in vitamin D levels. [Extracted from the article]

A recent umbrella review conducted by researchers at Saarland University Hospital in Germany explored the relationship between vitamin D levels and cancer. The review found inverse correlations between vitamin D levels and mortality for breast cancer, colorectal cancer, lung cancer, pancreatic cancer, and prostate cancer. There were also hints of a lower incidence of these cancers with higher vitamin D levels. However, the review noted that most studies included were observational, so causality cannot be determined. Methodological differences between studies also presented challenges. Overall, the review suggests a potential association between vitamin D levels and cancer outcomes, but further research is needed. [Extracted from the article]

A recent study conducted by the Department of Obstetrics and Gynecology explores the relationship between vitamin D deficiency and polycystic ovary syndrome (PCOS) in women. PCOS is a chronic disease that affects many women, and previous studies have suggested a connection between vitamin D levels and the development of PCOS. The researchers aimed to investigate this relationship further and also examine the impact of vitamin D deficiency on total cholesterol levels in patients attending Kirkuk General Hospital. For more information, the full study can be accessed through the Al-Kitab Journal for Pure Sciences. [Extracted from the article]

A recent study conducted at Diponegoro University examined the correlation between vitamin D deficiency, obesity, and impaired glucose metabolism in women with polycystic ovary syndrome (PCOS). The researchers found that there was no significant difference in vitamin D levels between women with PCOS and those without. However, they did find that obesity was strongly associated with PCOS, with women who had an obese waist circumference being 9.75 times more likely to develop the condition. The study concluded that while vitamin D deficiency is correlated with obesity, it does not correlate with impaired glucose metabolism. [Extracted from the article]

A study conducted in Adana, Turkey investigated the effects of vitamin D and mannitol in an experimental rat ovarian torsion model. The study found that the combination treatment of mannitol with vitamin D was more effective in reversing tissue damage caused by ischemia-reperfusion injury in the ovarian torsion model than administering only one agent. The study analyzed various factors such as total oxidant status, total antioxidant status, oxidative stress index, proliferating cell nuclear antigen levels, and histopathological analyses. The findings suggest potential benefits of this combination treatment in treating ovarian ischemia-reperfusion injury. [Extracted from the article]

A study conducted at the University of Hong Kong examined the association between serum vitamin D concentration and the risk of miscarriage in women with threatened miscarriage. The study analyzed stored serum samples from 371 women and found that low serum vitamin D concentration was not associated with an increased risk of miscarriage. However, the study did find that the miscarriage rate was significantly higher in the vitamin D non-deficient group compared to the vitamin D-deficient group in women who presented at 6 gestational weeks or earlier. Overall, the study concluded that a low serum vitamin D concentration was not associated with an increased risk of miscarriage in women with threatened miscarriage. [Extracted from the article]

This document provides information about an ongoing clinical trial that aims to investigate the effects of prebiotics and vitamin D3 on gestational diabetes mellitus (GDM) in high-risk pregnant women. The study plans to enroll 500 participants and is expected to be completed by December 31, 2026. The eligibility criteria for participants are outlined, and the primary investigators are listed as Gang Liu and An Pan from the Huazhong University of Science and Technology. The document also includes keywords related to the study, such as pharmaceuticals, wellness, metabolism, and public health. [Extracted from the article]

A study conducted by researchers at the Second Affiliated Hospital of Xi'an Jiaotong University in China explored the relationship between vitamin D levels and obesity in infertile women. The study analyzed data from the National Health and Nutrition Examination Survey (NHANES) and found that lower vitamin D levels were associated with a higher prevalence of obesity and abdominal obesity in infertile women. The researchers concluded that increasing vitamin D supplementation may be beneficial for obese infertile women. This study provides valuable insights into the potential role of vitamin D in managing obesity in this specific population. [Extracted from the article]

A recent study conducted by Khyber Medical University in Pakistan explored the association between vitamin D deficiency and the risk of developing preeclampsia in pregnant women. The study examined the genetic variations of the vitamin D receptor (VDR) gene and the levels of vitamin D in both preeclamptic and normotensive pregnant women. The results showed that there was no significant association between VDR gene polymorphism and the risk of preeclampsia. Additionally, the study found that the levels of vitamin D were low but comparable in both groups of women. Therefore, the study concluded that vitamin D deficiency and VDR gene polymorphism are not linked to the risk of preeclampsia. [Extracted from the article]

A recent study conducted at the University of Baghdad explored the relationship between vitamin D levels, lactate dehydrogenase (LDH) activity, and oxidative stress (OS) in postmenopausal women with osteoporosis. The study found that women with osteoporosis had higher levels of LDH and malondialdehyde (MDA), a marker of oxidative stress. There was also an inverse correlation between vitamin D levels and LDH and MDA levels, suggesting that vitamin D may possess antioxidant properties that can reduce the effects of oxidative stress. These findings highlight the potential role of vitamin D in reducing LDH levels and mitigating the impact of oxidative stress in women with osteoporosis. [Extracted from the article]

A new study conducted by researchers at the University of Tehran explores the association between a specific gene polymorphism and polycystic ovary syndrome (PCOS) in Iranian women. The study suggests that variations in the vitamin D binding protein (VDBP) gene and vitamin D deficiency may contribute to the development of PCOS. The research found statistically significant differences in the distribution of genotypes and alleles of the rs4588 polymorphism among the study groups, with the AC genotype and A allele showing an association with an increased risk of PCOS and infertility. However, no association was found between the genotypes and alleles of the rs4588 polymorphism and the risk of recurrent pregnancy loss (RPL) in women with PCOS. The study also observed that subjects with the AA or AC genotype had higher levels of LDL compared to those with the CC genotype. [Extracted from the article]

A recent report from the University of Witten Herdecke in Germany highlights the importance of magnesium in maternal-fetal health during pregnancy. Magnesium is essential for various physiological processes and plays a role in muscle relaxation, bone development, electrolyte balance, and blood pressure regulation. The research emphasizes the synergistic interactions between magnesium and other micronutrients like calcium, vitamin D, potassium, zinc, iron, and vitamin B6. Inadequate magnesium intake during pregnancy has been linked to complications such as gestational diabetes, preeclampsia, preterm birth, and low birth weight. The study suggests that maintaining adequate magnesium levels through a balanced diet and supplementation is crucial for optimal outcomes for both the mother and the fetus. [Extracted from the article]

A clinical trial, NCT06509776, is being conducted to investigate the factors that contribute to good bone health, hormonal health, muscle mass, and fat mass in young adults. The trial will measure bone mass, body composition, hormones, and epigenetic modifications to genes at birth. The study aims to understand how prenatal and childhood health influence these factors. Another study explores the relationship between birth weight and the risk of developing osteoporosis in adulthood, finding that higher birth weight is associated with an increased risk. Additionally, a research study is being conducted to investigate the relationship between DNA methylation and adiposity in individuals born in Denmark in 2006 or 2007. These studies contribute to our understanding of the factors that influence bone health and long-term health outcomes. [Extracted from the article]

A preprint abstract from biorxiv.org discusses the potential link between Vitamin D deficiency and reproductive outcomes. The study explores the effect of deficient levels of 1,25-(OH)2-D3, a form of Vitamin D, on ovarian cell function. The researchers found that low levels of 1,25-(OH)2-D3 may impair ovarian cell function and potentially affect folliculogenesis/ovulation. However, the impact of mild deficiency may be less significant, except in the presence of hyperinsulinemia and insulin resistance. The study also highlights the unique challenges of obtaining human thecal and unluteinised granulosa cells for research purposes. It is important to note that this preprint has not yet undergone peer review. [Extracted from the article]

A recent study conducted in Catanzaro, Italy, explored the correlation between bone mineral density, vitamin D deficiency, and oral health in women with breast cancer. The research found that breast cancer survivors treated with aromatase inhibitors often experience bone loss, poor oral health, and vitamin D deficiency. The study highlighted the importance of addressing oral health issues in these women, as chronic oral disorders may contribute to cancer treatment-induced bone loss. The researchers recommended vitamin D deficiency screening and supplementation, along with an appropriate oral rehabilitation strategy, as part of the comprehensive therapeutic approach for women with breast cancer receiving aromatase inhibitors. [Extracted from the article]

A recent report discusses the findings of a meta-analysis on the relationship between vitamin D levels and the risk of breast and endometrial cancers. The analysis, which included ten high-quality studies, found that higher vitamin D levels are associated with a lower risk of these cancers, particularly in premenopausal women and those with greater sun exposure. While some studies did not find significant links, the overall evidence supports the potential protective effect of vitamin D. Further randomized trials are needed to confirm these results and establish vitamin D deficiency standards in cancer risk assessment. [Extracted from the article]

A study conducted in Timisoara, Romania, explored the relationship between vitamin D deficiency and arterial stiffness in pregnant women with preeclampsia and pregnancy-induced hypertension. The study found that pregnant women with hypertension had higher values for arterial stiffness compared to those with preeclampsia. Severe vitamin D deficiency was associated with increased chances of preterm birth and worse arterial stiffness parameters. The researchers suggest that assessing maternal arterial stiffness using pulse wave analysis could help identify patients at higher risk and prevent negative impacts on fetal development. [Extracted from the article]

This document provides information about a clinical trial, NCT06504966, that is currently underway to compare the effectiveness and safety of two drugs, MAB-22 and Prolia(R), in postmenopausal women with osteoporosis. The trial aims to demonstrate that MAB-22 is similar and not inferior to Prolia(R) in terms of bone density and collagen levels. The study is still in the recruitment phase and is expected to be completed by October 2026. The trial is being conducted by Xentria, Inc. and is regulated by the U.S. FDA. [Extracted from the article]

A recent study conducted in Isfahan, Iran, explored the effects of vitamin D intake on metabolic profiles in infertile women with polycystic ovary syndrome (PCOS). The study involved 40 participants who were randomly divided into two groups, with one group receiving 50,000 IU of vitamin D weekly for eight weeks and the other group receiving a placebo. The results showed that vitamin D intake led to a decrease in high-sensitivity C-reactive protein (hs-CRP) levels and an increase in total antioxidant capacity (TAC) levels. Additionally, the expression of tumor necrosis factor alpha (TNF-a) was significantly downregulated in the group that received vitamin D. Overall, the study suggests that vitamin D intake may have beneficial effects on inflammation and oxidative stress in infertile women with PCOS. [Extracted from the article]

A recent report from Hashemite University in Jordan explores the association between vitamin D levels during pregnancy and postpartum depression (PPD). The researchers conducted a narrative review of studies published between 2012 and 2022, finding that pregnant women with vitamin D deficiency (VDD) were significantly associated with PPD. The study suggests that screening vitamin D levels among pre- and postnatal mothers may be important for awareness programs and promoting remission of postnatal depression. Further longitudinal studies are needed to evaluate the relationship between VDD and PPD. [Extracted from the article]

A recent report discusses the findings of a study conducted at Anhui Medical University in Hefei, China, on the effects of vitamin D supplementation on pregnant women with gestational diabetes mellitus (GDM) or obesity. The researchers aimed to determine if vitamin D supplementation could improve gestational cardiovascular health (CVH) in these high-risk women. The study involved 1,537 participants who were randomly assigned to receive either 1600 IU/d or 400 IU/d of vitamin D3 for two months. The results showed that vitamin D supplementation improved certain cardiovascular markers in the intervention group, particularly in women with GDM or obesity. The researchers concluded that vitamin D supplementation during mid-gestation could optimize gestational CVH and potentially prevent cardiovascular disease in the future. [Extracted from the article]

A study conducted by researchers at Mashhad University of Medical Sciences in Iran investigated the relationship between post-treatment breast pain severity in breast cancer patients and serum vitamin D and hs-CRP levels. The study found that high levels of hs-CRP, an inflammatory marker, were positively correlated with increased pain intensity. However, no significant association was observed between different serum concentrations of vitamin D and pain intensity. The research suggests that elevated levels of inflammatory factors, such as hs-CRP, may increase the likelihood of developing chronic post-surgical pain. [Extracted from the article]

A recent study conducted by researchers from King's College London examined the effect of micronutrient supplementation interventions in women at high risk of developing pre-eclampsia, a condition that can lead to maternal and neonatal complications. The study found that calcium and vitamin D supplementation were associated with a lower rate of pre-eclampsia. However, the conclusions were limited due to small sample sizes, methodological variability, and heterogeneity between studies. The researchers recommend further large-scale randomized controlled trials to explore interventions at different time points before and during pregnancy and to utilize prediction modeling methodology for a better understanding of the efficacy of micronutrient supplementation in preventing pre-eclampsia in high-risk women. [Extracted from the article]

A recent study conducted by researchers at the Cancer Research Institute explored the potential protective effect of vitamin D on ovarian reserve in breast cancer patients undergoing chemotherapy. The study involved 33 patients and found that there was no significant improvement in anti-Mullerian hormone (AMH) levels after six months of chemotherapy in the group that received vitamin D supplementation compared to the control group. The researchers concluded that further larger studies are needed to evaluate the effect of vitamin D supplements on ovarian reserve in breast cancer patients undergoing chemotherapy. [Extracted from the article]

A recent study conducted by Zhejiang University School of Medicine aimed to investigate the potential causal link between vitamin D levels and postpartum depression (PPD). The study utilized genetic data from cohorts and employed bidirectional Mendelian Randomization (MR) analysis. The results of the study revealed no substantial genetic correlation between serum 25-hydroxyvitamin D levels and PPD, suggesting the absence of a causal link. The researchers concluded that inconsistent findings in previous observational studies may be due to residual confounding. [Extracted from the article]

A recent study conducted in Saudi Arabia found a correlation between vitamin D deficiency and multiple sclerosis (MS). The study, which included 200 MS patients and 160 healthy participants, revealed that 73.02% of MS patients had deficient levels of vitamin D. Additionally, the research found that female gender and age under 40 were statistically significant risk factors for MS. The study suggests that the prevalence of MS is higher among women and younger individuals in high-altitude populations in Saudi Arabia. [Extracted from the article]

A recent study conducted at the Medical University of South Carolina examined the effects of vitamin D supplementation on postpartum women's bone mineral density (BMD) during lactation. The study found that lactating women experienced a 1-3% loss in BMD compared to non-lactating women who gained BMD. Higher maternal BMI was associated with less bone loss in certain regions, and black American women had less BMD loss than white/Caucasian or Hispanic lactating women. The study also found that higher vitamin D supplementation appeared to protect against BMD loss in the femoral neck. Overall, the study highlights the importance of vitamin D and other factors in maintaining bone health during the postpartum period. [Extracted from the article]

2023 JUN 15 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Investigators discuss new findings in obesity. According to news reporting originating from Padang, Indonesia, [...]

2023 APR 27 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Researchers detail new data in vitamin D deficiency. According to news reporting originating from [...]

2023 FEB 16 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- New study results on COVID-19 have been published. According to news originating from Aristotle [...]

2023 JAN 12 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Investigators discuss new findings in pediatrics. According to news reporting out of Lansing, Michigan, [...]

A recent study conducted by the Hull York School of Medicine explored the relationship between vitamin D levels and cardiovascular risk biomarkers in non-obese women with and without polycystic ovary syndrome (PCOS). The study found that women with PCOS had higher levels of certain cardiovascular risk proteins, indicating an underlying inflammatory process, even in the absence of obesity and insulin resistance. Additionally, vitamin D levels were correlated with some cardiovascular risk proteins in both groups. These findings suggest that vitamin D deficiency and inflammation may play a role in the cardiovascular health of women with PCOS. [Extracted from the article]

A study conducted in South India explored the association between serum vitamin D and anti-Mullerian hormone (AMH) levels in women with polycystic ovary syndrome (PCOS). The study included 120 women with PCOS and 60 controls. The results showed no significant difference in vitamin D levels between the PCOS and control groups. However, there was a weak positive correlation between vitamin D levels and AMH levels in the PCOS group. The study concluded that AMH levels were independently correlated with age, but not with vitamin D. [Extracted from the article]

A recent study examined the effectiveness of vitamin D in preventing breast cancer in young women. The study found that vitamin D supplementation reduced tumor size and promoted anti-tumor immunity in never-pregnant mice. However, these effects were not observed in a mouse model of postpartum breast cancer, where altered liver metabolism resulted in deficient levels of vitamin D. The study suggests that vitamin D's anti-tumor activity is mediated through immunomodulatory mechanisms and may not be effective in the post-wean window. These findings have implications for understanding xenobiotic metabolism in postpartum women. [Extracted from the article]

A report from the Ditmanson Medical Foundation Chia-Yi Christian Hospital discusses the effects of vitamin D deficiency in pregnancy on maternal and offspring health-related outcomes. The researchers conducted an umbrella review of systematic reviews and meta-analyses on this topic and found that vitamin D deficiency in pregnancy is associated with an increased risk of preterm birth, small-for-gestational age/low birth weight infants, recurrent miscarriage, bacterial vaginosis, and gestational diabetes mellitus. However, vitamin D supplementation during pregnancy can increase birth weight and reduce the risk of maternal pre-eclampsia, miscarriage, vitamin D deficiency, fetal or neonatal mortality, attention-deficit hyperactivity disorder, and autism spectrum disorder in childhood. The researchers recommend monitoring the vitamin D status in pregnancy, especially in women at high risk of deficiency, and suggest taking a dose of >400 IU/day of vitamin D supplementation during pregnancy to prevent adverse outcomes. [Extracted from the article]