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Your search keyword '"Kenneth G. Carson"' showing total 2 results
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2 results on '"Kenneth G. Carson"'

1. Studies on morpholinosphingolipids: Potent inhibitors of glucosylceramide synthase

Author

Bruce Ganem, Akira Abe, Norman S. Radin, James A. Shayman, and Kenneth G. Carson

Subjects
Ceramide, chemistry.chemical_compound, Biochemistry, Stereochemistry, Chemistry, Organic Chemistry, Drug Discovery, Absolute configuration, Glucosylceramide synthase
Abstract

Synthetic 1-morpholino-1-deoxyceramides were designed to inhibit glucosylceramide synthase. The most potent inhibitor 2a possesses the unnatural R,R-configuration of D-threo-sphingosine.

Published
1994
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2. Reductive amination of aldehydes and ketones by using sodium triacetoxyborohydride

Author

Ahmed F. Abdel-Magid, Cynthia A. Maryanoff, and Kenneth G. Carson

Subjects
chemistry.chemical_classification, Ketone, Organic Chemistry, Biochemistry, Aldehyde, Reductive amination, Sodium triacetoxyborohydride, chemistry.chemical_compound, chemistry, Reagent, Drug Discovery, Organic chemistry, Amine gas treating, Aliphatic compound, Amination
Abstract

Sodium triacetoxyborohydride is a reagent of choice in the reductive amination of aldehydes and saturated aliphatic ketones with primary and secondary amines. Sodium triacetoxyborohydride was successfully used in the reductive amination of variety of aldehydes and ketones with primary and secondary amines.

Published
1990
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