Search

Your search keyword '"Estrane"' showing total 4 results
Start Over Descriptor "Estrane" Journal tetrahedron letters
4 results on '"Estrane"'

1. Synthesis of 11α-methyl-11β-(arylethynyl) substituted steroids of the estrane series

Author

Arwed Cleve, Rudolf Wiechert, Wolfgang Schwede, and Eckhard Ottow

Subjects
chemistry.chemical_compound, chemistry, Estrane, medicine.medical_treatment, Organic Chemistry, Drug Discovery, Acetal, medicine, Propyne, Biochemistry, Combinatorial chemistry, Enone, Steroid
Abstract

The synthesis of 11α-methyl-11β-(arylethynyl) substituted 19-norsteroids of 13, 14, and 15 is described. The preparation of these compounds opens for the first time an approach to 11-disubstituted antiprogestins.

Published
1993

2. A five step synthesis of (d,l)-estrane derivatives from 1,3-butadiene

Author

Hélène Pellissier, Maurice Santelli, and Pierre Yves Michellys

Subjects
Bicyclic molecule, Intramolecular reaction, Chemistry, Stereochemistry, Organic Chemistry, 1,3-Butadiene, Alkylation, Biochemistry, chemistry.chemical_compound, Spirolactone, Estrane, Drug Discovery, Stereoselectivity, Aliphatic compound
Abstract

A spirolactone 2 , obtained in two steps from 1,3-butadiene (ca. 50 %), was methoxycarbonylated (LiHMDS / dimethylcarbonate) and alkylated with iodo

Published
1993

3. A novel fragmentation-cyclization reaction of steroidal α-hydroxy oximes

Author

Julijana Petrovic, Evgenija Durendic, Katarina Penov-Gaši, Vjera Pejanovic, Ljubica Medić-Mijačević, Dušan Lazar, Slobodanka Stanković, and Dušan Miljković

Subjects
chemistry.chemical_compound, Fragmentation (mass spectrometry), Chemistry, Estrane, Organic Chemistry, Drug Discovery, Androstane, Biochemistry, Medicinal chemistry
Abstract

By a novel “one pot” fragmentation-cyclization reaction 17β-hydroxy-17α-substituted-16-oximino derivatives in the androstane and estrane series were converted to a new type of D-homo derivative.

Published
1998

4. A novel rearrangement of steroidal α-hydroxy oximes

Author

Ljubica Medić-Mijačević, Dušan Miljković, Evgenija A. Djurendić, Dušan Lazar, Slobodanka Stanković, Vjera Pejanovic, Marija N. Sakač, and Katarina Penov-Gaši

Subjects
chemistry.chemical_compound, chemistry, Stereochemistry, Estrane, Titanium trichloride, Organic Chemistry, Drug Discovery, Androstane, Biochemistry
Abstract

By the action of acidic titanium trichloride upon 16-oximino-17α-benzyl-17β-hydroxy derivatives in the androstane and estrane series the 16-oxo-17β-benzyl-17α-hydroxy derivatives 6 and 7 with inversed configuration at C 17 were obtained. A mechanism for this novel rearrangement is proposed.

Published
1997

Catalog

Books, media, physical & digital resources
See catalog results