1. Seeking markers to distinguish HCV-infected-autoimmune subjects from uninfected-autoimmune patients
- Author
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Amany S. Maghraby, Solaf A. Kamel, Dalia B. Fayed, Heba Shawky, Mona A. Razin, Rola N. Abd-Elshafy, Azza F. Arafa, Dina N. Abd-Elshafy, and Mahmoud M. Bahgat
- Subjects
Medicine (General) ,R5-920 - Abstract
Introduction — Egypt has the highest prevalence of hepatitis C virus (HCV) infection which is reported to be associated with autoimmune manifestations. Aim — There is a need for markers that enable differentiation between viral and non-infected-autoimmune patients. Material and Methods — Levels of the B-cell activation factor (BAFF), IL6, IL10 and TNF-α were quantified by ELISA in sera from HCV-infected-autoimmune patients (HCV-AI), HCV-infected patients with no autoimmune diseases (HCV-NAI), non-infected autoimmune patients (NIAI) and healthy control humans (C). Results — HCV-infected patients were 12.96, 8.33, 69.44 and 36.11% positive for the auto-antibodies ANA, AMA, ASMA and AGPCA respectively. The BAFF level was significantly (P
- Published
- 2019
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