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Seeking markers to distinguish HCV-infected-autoimmune subjects from uninfected-autoimmune patients
- Source :
- Russian Open Medical Journal, Vol 8, Iss 3, p e0308 (2019)
- Publication Year :
- 2019
- Publisher :
- Limited liability company «Science and Innovations» (Saratov), 2019.
-
Abstract
- Introduction — Egypt has the highest prevalence of hepatitis C virus (HCV) infection which is reported to be associated with autoimmune manifestations. Aim — There is a need for markers that enable differentiation between viral and non-infected-autoimmune patients. Material and Methods — Levels of the B-cell activation factor (BAFF), IL6, IL10 and TNF-α were quantified by ELISA in sera from HCV-infected-autoimmune patients (HCV-AI), HCV-infected patients with no autoimmune diseases (HCV-NAI), non-infected autoimmune patients (NIAI) and healthy control humans (C). Results — HCV-infected patients were 12.96, 8.33, 69.44 and 36.11% positive for the auto-antibodies ANA, AMA, ASMA and AGPCA respectively. The BAFF level was significantly (P
- Subjects :
- Medicine (General)
R5-920
Subjects
Details
- Language :
- English
- ISSN :
- 23043415
- Volume :
- 8
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Russian Open Medical Journal
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.29f7669632694823bc0b1b251c02715d
- Document Type :
- article
- Full Text :
- https://doi.org/10.15275/rusomj.2019.0308