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Start Over Author "Domingos Alves Meira" Journal revista do instituto de medicina tropical de sao paulo
13 results on '"Domingos Alves Meira"'

1. Liver dysfunction in patients bitten by Crotalus durissus terrificus (Laurenti, 1768) snakes in Botucatu (State of São Paulo, Brazil) Alterações hepáticas em doentes picados por serpentes Crotalus durissus terrificus (Laurenti, 1768) na região de Botucatu, Estado de São Paulo, Brasil

Author

Benedito Barra Viera, Kunie Yabuki Rabello Coelho, Paulo Roberto Curi, and Domingos Alves Meira

Subjects
Ophidic accidents, Crotalus durissus terrificus, Liver dysfunction, Bromsulphalein test, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216
Abstract

Thirty-two patients bitten by venomous snakes sixteen by Bothrops spp. and sixteen by Crotalus durissus terrificus were studied. The group comprised thirty males and two females, aged eight to sixty-three years (mean 33±15). Bromsulphalein tests were increased in the majority of patients bitten by Crotalus durissus terrificus. The correlation coefficient of Spearman was positive between bromsulphalein tests and alanine aminotransferase levels, and between alanine aminotransferase and aspartate aminotransferase levels only in the Crotalus group. The only patient who died was bitten by Crotalus durissus terrificus and showed hydropic degeneration and mitochondrial injury in the liver. It was concluded that the hepatic damage might have been caused by at least two possible mechanisms: venom effect on liver mitochondria and cytokine effects on hepatocyte, specially interleukin-6.Os autores estudaram 32 doentes picados por serpentes venenosas, sendo 16 picados por Bothrops spp. e 16 por Crotalus durissus terrificus. Trinta doentes eram do sexo masculino e dois do feminino com idades variando entre 8 e 63 anos (méda 33±15). A prova da retenção da bromosulfaleína apresentou-se aumentada na maioria dos doentes picados por serpentes Crotalus durissus terrificus. Houve correlação positiva entre a retenção da bromosulfaleína e os níveis séricos de alanina aminotransferase e entre alanina e aspartato aminotransferase apenas nos doentes do grupo Crotalus. Um dos doentes evoluiu para o óbito e apresentou no exame anatomopatológico do fígado degeneração hidrópica e lesões mitocondriais. Os autores concluem que as alterações hepáticas são causadas por pelo menos dois mecanismos a saber: lesão mitocondrial por efeito do veneno crotálico; efeito das citoquinas, especialmente a interleucina-6.

Published
1995
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3. Paracoccidioidomicose subaguda progressiva: tratamento de um doente com anfotericina B e nutrição parenteral

Author

Paulo Camara Marques Pereira, Benedito Barraviera, Jussara Marcondes, Celso Vieira Souza Leite, Domingos Alves Meira, Tadasi Inoue, and José Morceli

Subjects
Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216
Abstract

Os Autores descrevem um caso de paracoccidioidomicose subaguda progressiva, com quadro clínico sugestivo de síndrome de má absorção, em que o doente não se beneficiara apenas com o tratamento antifúngico convencional. Ao se introduzir como medida auxiliar a nutrição parenteral houve evidente melhora clínica e laboratorial. Desta maneira os Autores propõe o uso associado da nutrição parenteral no tratamento de doentes com esta forma clínica de paracoccidioidomicose.

Published
1985
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4. Avaliação Do Tratamento Da Paracoccidioidomicose Com O Ketoconazol

Author

Jussara Marcondes, Domingos Alves Meira, Rinaldo Poncio Mendes, Paulo Camara Marques Pereira, Benedito Barraviera, Norma Gerusa da Silva Mota, and José Morceli

Subjects
Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216
Abstract

Foram, tratados 12 doentes atendidos na Disciplina de Moléstias Infecciosas e Parasitárias da Faculdade de Medicina de Botucatu com diagnóstico etiológico de paracoccidioidomicose que apresentavam lesões orgânicas múltiplas e evolução prolongada. O tratamento foi realizado por 18 meses, com o ketoconazol, pela via oral, nas doses diárias de 400 mg no primeiro mês e de 200 mg nos meses seguintes. Todos os doentes foram acompanhados durante o tratamento e, em média 4 meses e meio após o mesmo, clínica, radiológica e sorologicamente pelas reações de imunofluorescência indireta, precipitinas e imunodifusão em gel. A competência imunitária foi avaliada em todos os doentes antes do tratamento e repetida em quatro, no final do mesmo. Os resultados mostraram que houve recaída em 5 doentes. A droga foi bem tolerada e a imunodifusão em gel e a hemossedimentação foram as provas que mostraram maior paralelismo com a evolução clínica.

Published
1984
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5. Malária no município de Humaitá, estado do Amazonas: XXI. Prevalência da deficiência de glicose-6-fosfato desidrogenase (G6PD) Em amostra da população e em doentes com malaria causada pelo Plasmodium falciparum

Author

Benedito Barraviera, Domingos Alves Meira, Paulo Eduardo de Abreu Machado, and Paulo Roberto Curi

Subjects
Malária, Glicose-6-fosfato desidrogenase (G6PD), Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216
Abstract

Os autores estudaram a prevalência da deficiência de glicose-6-fosfato desidrogenase (G6PD), pelo método de BREWER et alii, em 141 indivíduos da população do município de Humaitá, Estado do Amazonas. Destes, 128 eram amazônides, 67 dos quais nunca tiveram malária, enquanto que 61 tinham tido ou estavam tendo a doença; os 13 restantes que estavam com malária não eram arnazônides. Os resultados revelaram que 7 arnazônides (4,96%), eram deficientes. Destes, 5 eram do sexo feminino e 2 do masculino. Em todos os indivíduos do sexo feminino o teste foi positivo com comportamento do tipo heterozigoto. Dos indivíduos deficientes, 4 nunca tinham tido malária; dos outros 3, 2 apresentavam a reação de hemaglutinação positiva com título 1/16 e o terceiro estava tendo malária causada pelo Plasmodium falciparum pela primeira vez. Este doente apresentou forma benigna de malária evoluindo para cura clínica e parasitológica no 3.° dia de tratamento com a clindamicina. Nenhum dos 13 doentes não arnazônides apresentava deficiência de G6PD. Dessa forma, não houve diferença na prevalência da deficiência de G6PD em arnazônides que nunca tiveram malária e em arnazônides que tinham tido ou estavam tendo a doença. Portanto, os indivíduos com deficiência de G6PD estão sujeitos a infecções por Plasmodium falciparum na mesma proporção que os não deficientes. Por outro lado, o aumento da prevalência da deficiência de G6PD, na amostra estudada, poderia estar relacionado com a pressão seletiva exercida pela malária em população submetida à homozigose.

Published
1987
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6. Glucose-6-phosphate dehydrogenase and glutathione reductase activity in methemoglobin reduction by methylene blue and cyst amine: study on glucose-6-phosphate dehydrogenase-deficient individuals, on normal subjects and on riboflavin-treated subjects

Author

Benedito Barraviera, Paulo Eduardo de Abreu Machado, Domingos Alves Meira, Paulo Roberto Curi, Jair Natal Pires Martins, and Maria Júlia de Souza

Subjects
Glucose-6-phosphate dehydrogenase, Glutathione reductase, Methemoglobin, Cystamine, Riboflavin, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216
Abstract

The authors have standardized methods for evaluation of the activity of the glucose-6-phosphate dehydrogenase and of glutathione reductase. The general principle of the first method was based on methemoglobin formation by sodium nitrite followed by stimulation of the glucose-6-phosphate dehydrogenase with methylene blue. Forty six adults (23 males and 23 females) were studied. Subjects were not G6PD deficient and were aged 20 to 30 years. The results showed that methemoglobin reduction by methylene blue was 154.40 and 139.90 mg/min (p

Published
1988
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7. Malaria at Humaita county, Amazonas state, Brazil: XVII — immune response in patients with Plasmodium falciparum according to gametocytes

Author

Domingos Alves Meira, Paulo Roberto Curi, Jussara Marcondes, Elinda Satie Matsuoka, Marina A. Favrin, Albert Boutros El-Khoury, and Norma Gerusa da Silva Motta

Subjects
Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216
Abstract

In August 1983 the Authors studied 36 patients with Plasmodium falciparum malaria and 14 normal individuals born in Humaita region who had never had malaria, had no spleen enlargement and had negative parasitemia as well as passive hemagglutination. Medical histories were obtained and complete physical examination were performed in all of them just as blood tests, parasite density and lymphocyte typing. The lymphocytes were separated and then frozen in liquid nitrogen for later typing by rosette formation. The patients were divided in two groups according to the presence (13 patients) or abscence (23 patients) of gametocytes before treatment. Severe malaria was predominant in the group without gametocytes. The results showed a decrease in the T-cell numbers in Plasmodium falciparum acute malaria patients both with or without gametocytes before the treatment, while B-cell numbers were normal only in the patients with gametocytes. These observations as like as those previously reported by the Authors, permit to associate the presence of gametocytes in peripheral blood and normal number of B-cells in patients with mild Plasmodium falciparum malaria.

Published
1985
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11. Glucose-6-phosphate dehydrogenase and glutathione reductase activity in methemoglobin reduction by methylene blue and cyst amine: study on glucose-6-phosphate dehydrogenase-deficient individuals, on normal subjects and on riboflavin-treated subjects

Author

Maria Julia de Souza, Paulo Eduardo de Abreu Machado, Jair Natal Pires Martins, Benedito Barraviera, Domingos Alves Meira, Paulo Roberto Curi, and Universidade Estadual Paulista (Unesp)

Subjects
Adult, Male, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, Riboflavin, Cystamine, Glucosephosphate Dehydrogenase, Methemoglobin, chemistry.chemical_compound, Sex Factors, hemic and lymphatic diseases, Humans, Glucose-6-phosphate dehydrogenase, Glutathione reductase, Sodium Nitrite, General Medicine, Molecular biology, Methylene Blue, Glucosephosphate Dehydrogenase Deficiency, Infectious Diseases, chemistry, Glutathione reductase activity, Female, Oxidation-Reduction, Methylene blue
Abstract

Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T19:03:58Z No. of bitstreams: 1 S0036-46651988000500007.pdf: 1487021 bytes, checksum: 0e2401a88a0a70b9f3b328b7daa7adec (MD5) Made available in DSpace on 2013-08-22T19:03:58Z (GMT). No. of bitstreams: 1 S0036-46651988000500007.pdf: 1487021 bytes, checksum: 0e2401a88a0a70b9f3b328b7daa7adec (MD5) Previous issue date: 1988-10-01 Made available in DSpace on 2013-09-30T18:18:52Z (GMT). No. of bitstreams: 2 S0036-46651988000500007.pdf: 1487021 bytes, checksum: 0e2401a88a0a70b9f3b328b7daa7adec (MD5) S0036-46651988000500007.pdf.txt: 36021 bytes, checksum: e60fefb2f692d4995e0096154ad50957 (MD5) Previous issue date: 1988-10-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T13:32:34Z No. of bitstreams: 2 S0036-46651988000500007.pdf: 1487021 bytes, checksum: 0e2401a88a0a70b9f3b328b7daa7adec (MD5) S0036-46651988000500007.pdf.txt: 36021 bytes, checksum: e60fefb2f692d4995e0096154ad50957 (MD5) Made available in DSpace on 2014-05-20T13:32:34Z (GMT). No. of bitstreams: 2 S0036-46651988000500007.pdf: 1487021 bytes, checksum: 0e2401a88a0a70b9f3b328b7daa7adec (MD5) S0036-46651988000500007.pdf.txt: 36021 bytes, checksum: e60fefb2f692d4995e0096154ad50957 (MD5) Previous issue date: 1988-10-01 Os autores padronizaram métodos para a avaliação da atividade da glicose-6-fosfato desidrogenase e glutationa redutase. O princípio geral do primeiro método baseou-se na formação de metahemoglobina pelo nitrito de sódio, seguido da estimulação da via das pentoses pelo azul de metileno. Foram estudados 46 indivíduos adultos, sendo 23 do sexo masculino e 23 do feminino, não deficientes em glicose-6-fosfato desidrogenase (G6PD), com idades variando entre 20 e 30 anos. Os resultados revelaram que a redução da metahemoglobina pelo azul de metileno para sangue total, foram de 154.50 e 139.90 mg/min (p

Published
1988
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12. Malaria in the Humaitá County, Amazonas State, XXI. Prevalence of glucose-6-phosphate dehydrogenase deficiency in a population sample and in malaria patients (Plasmodium falciparum)

Author

Paulo Roberto Curi, Benedito Barraviera, Domingos Alves Meira, Paulo Eduardo de Abreu Machado, and Universidade Estadual Paulista (Unesp)

Subjects
Gynecology, medicine.medical_specialty, lcsh:Arctic medicine. Tropical medicine, Population sample, biology, lcsh:RC955-962, Plasmodium falciparum, Malária, General Medicine, biology.organism_classification, medicine.disease, Infectious Diseases, Glicose-6-fosfato desidrogenase (G6PD), medicine, Malaria, Glucose-6-phosphate dehydrogenase deficiency
Abstract

Os autores estudaram a prevalência da deficiência de glicose-6-fosfato desidrogenase (G6PD), pelo método de BREWER et alii, em 141 indivíduos da população do município de Humaitá, Estado do Amazonas. Destes, 128 eram amazônides, 67 dos quais nunca tiveram malária, enquanto que 61 tinham tido ou estavam tendo a doença; os 13 restantes que estavam com malária não eram arnazônides. Os resultados revelaram que 7 arnazônides (4,96%), eram deficientes. Destes, 5 eram do sexo feminino e 2 do masculino. Em todos os indivíduos do sexo feminino o teste foi positivo com comportamento do tipo heterozigoto. Dos indivíduos deficientes, 4 nunca tinham tido malária; dos outros 3, 2 apresentavam a reação de hemaglutinação positiva com título 1/16 e o terceiro estava tendo malária causada pelo Plasmodium falciparum pela primeira vez. Este doente apresentou forma benigna de malária evoluindo para cura clínica e parasitológica no 3.° dia de tratamento com a clindamicina. Nenhum dos 13 doentes não arnazônides apresentava deficiência de G6PD. Dessa forma, não houve diferença na prevalência da deficiência de G6PD em arnazônides que nunca tiveram malária e em arnazônides que tinham tido ou estavam tendo a doença. Portanto, os indivíduos com deficiência de G6PD estão sujeitos a infecções por Plasmodium falciparum na mesma proporção que os não deficientes. Por outro lado, o aumento da prevalência da deficiência de G6PD, na amostra estudada, poderia estar relacionado com a pressão seletiva exercida pela malária em população submetida à homozigose. The authors studied the prevalence of glucoses-phosphate dehydrogenase (G6PD) deficiency by BREWER method et al, in 141 individuals from Humaita county, Amazonas State. From this total, 128 were born in Amazonian 67 had never had malaria, but 61 had already had this disease or were with; it the others thirteen left, who had this disease were not from Amazonian. The results revealed that 7 (4,96%) Amazonian individuals were deficients. From this total, there were 5 females and 2 males individuals. In all female individuals the test was positive according to heterozygote kind of behaviour. Among the deficient individuals, four had never had malaria from the 3 left, 2 presented a positive hemagglutination reaction with 1/16 tittle and the third was with malaria for the first time, caused by Plasmodium falciparum. This patient presented the benign form of malaria followed by clinical and parasitological remission in the third day of treatment with clindamycin. None of the 13 patients who weren't Amazonian individuals presented G6PD deficiency. Being so, there were no diference in the prevalence of G6PD in Amazonian individuals who had never had the disease and in Amazonian individuals who had already had or were with the disease. Thus, the individuals with G6PD deficiency are subject to contamination by Plasmodium falciparum in the same proportion to the no deficients. In the other hand, the increase of prevalence of G6PD deficiency in the sample studied, could be related to the seletive pressure on malaria in population submited to homozygous.

Published
1987

13. Neurocysticercosis: treatment with albendazole and dextrochloropheniramine (preliminary report)

Author

Paulo Câmara Marques Pereira, Rinaldo Poncio Mendes, Jussara Marcondes Machado, Benedito Barra Viera, Domingos Alves Meira, Paulo Roberto Curi, Svetlana Agapejev, Amélia Kamegasawa, and Universidade Estadual Paulista (Unesp)

Subjects
Pediatrics, medicine.medical_specialty, Chlorpheniramine, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, Neurocysticercosis, Albendazole, Preliminary report, Central Nervous System Diseases, medicine, Humans, Alternative program, Anthelmintics, Clinical Trials as Topic, business.industry, Cysticercosis, General Medicine, medicine.disease, Praziquantel, Infectious Diseases, Immunology, Benzimidazoles, Drug Therapy, Combination, business, medicine.drug
Abstract

Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T19:03:59Z No. of bitstreams: 1 S0036-46651988000500010.pdf: 401601 bytes, checksum: 9cf04531b0af31ba123b3d3b180ab9cc (MD5) Made available in DSpace on 2013-08-22T19:03:59Z (GMT). No. of bitstreams: 1 S0036-46651988000500010.pdf: 401601 bytes, checksum: 9cf04531b0af31ba123b3d3b180ab9cc (MD5) Previous issue date: 1988-10-01 Made available in DSpace on 2013-09-30T20:06:31Z (GMT). No. of bitstreams: 2 S0036-46651988000500010.pdf: 401601 bytes, checksum: 9cf04531b0af31ba123b3d3b180ab9cc (MD5) S0036-46651988000500010.pdf.txt: 11866 bytes, checksum: 3120b4bb760218d1fe810a91055ac5d3 (MD5) Previous issue date: 1988-10-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T13:36:03Z No. of bitstreams: 2 S0036-46651988000500010.pdf: 401601 bytes, checksum: 9cf04531b0af31ba123b3d3b180ab9cc (MD5) S0036-46651988000500010.pdf.txt: 11866 bytes, checksum: 3120b4bb760218d1fe810a91055ac5d3 (MD5) Made available in DSpace on 2014-05-20T13:36:03Z (GMT). No. of bitstreams: 2 S0036-46651988000500010.pdf: 401601 bytes, checksum: 9cf04531b0af31ba123b3d3b180ab9cc (MD5) S0036-46651988000500010.pdf.txt: 11866 bytes, checksum: 3120b4bb760218d1fe810a91055ac5d3 (MD5) Previous issue date: 1988-10-01 UNESP Faculty of Medicine of Botucatu Department of Neurology and Psychiatry UNESP Faculty of Medicine of Botucatu Department of Infectious and Parasitic Diseases UNESP) Faculty of Medicine of Botucatu Department of Ophthalmology and Otorhinolaryngology UNESP Faculty of Medicine of Botucatu UNESP Faculty of Medicine of Botucatu Department of Neurology and Psychiatry UNESP Faculty of Medicine of Botucatu Department of Infectious and Parasitic Diseases UNESP) Faculty of Medicine of Botucatu Department of Ophthalmology and Otorhinolaryngology UNESP Faculty of Medicine of Botucatu

Published
1988

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