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Glucose-6-phosphate dehydrogenase and glutathione reductase activity in methemoglobin reduction by methylene blue and cyst amine: study on glucose-6-phosphate dehydrogenase-deficient individuals, on normal subjects and on riboflavin-treated subjects
- Source :
- Revista do Instituto de Medicina Tropical de São Paulo, Vol 30, Iss 5, Pp 370-378 (1988), Revista do Instituto de Medicina Tropical de São Paulo, Volume: 30, Issue: 5, Pages: 370-378, Published: OCT 1988, Revista do Instituto de Medicina Tropical de São Paulo; Vol. 30 No. 5 (1988); 370-378, Revista do Instituto de Medicina Tropical de São Paulo; Vol. 30 Núm. 5 (1988); 370-378, Revista do Instituto de Medicina Tropical de São Paulo; v. 30 n. 5 (1988); 370-378, Revista do Instituto de Medicina Tropical de São Paulo, Instituto de Medicina Tropical (IMT), instacron:IMT, SciELO, Repositório Institucional da UNESP, Universidade Estadual Paulista (UNESP), instacron:UNESP
- Publication Year :
- 1988
- Publisher :
- FapUNIFESP (SciELO), 1988.
-
Abstract
- Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T19:03:58Z No. of bitstreams: 1 S0036-46651988000500007.pdf: 1487021 bytes, checksum: 0e2401a88a0a70b9f3b328b7daa7adec (MD5) Made available in DSpace on 2013-08-22T19:03:58Z (GMT). No. of bitstreams: 1 S0036-46651988000500007.pdf: 1487021 bytes, checksum: 0e2401a88a0a70b9f3b328b7daa7adec (MD5) Previous issue date: 1988-10-01 Made available in DSpace on 2013-09-30T18:18:52Z (GMT). No. of bitstreams: 2 S0036-46651988000500007.pdf: 1487021 bytes, checksum: 0e2401a88a0a70b9f3b328b7daa7adec (MD5) S0036-46651988000500007.pdf.txt: 36021 bytes, checksum: e60fefb2f692d4995e0096154ad50957 (MD5) Previous issue date: 1988-10-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T13:32:34Z No. of bitstreams: 2 S0036-46651988000500007.pdf: 1487021 bytes, checksum: 0e2401a88a0a70b9f3b328b7daa7adec (MD5) S0036-46651988000500007.pdf.txt: 36021 bytes, checksum: e60fefb2f692d4995e0096154ad50957 (MD5) Made available in DSpace on 2014-05-20T13:32:34Z (GMT). No. of bitstreams: 2 S0036-46651988000500007.pdf: 1487021 bytes, checksum: 0e2401a88a0a70b9f3b328b7daa7adec (MD5) S0036-46651988000500007.pdf.txt: 36021 bytes, checksum: e60fefb2f692d4995e0096154ad50957 (MD5) Previous issue date: 1988-10-01 Os autores padronizaram métodos para a avaliação da atividade da glicose-6-fosfato desidrogenase e glutationa redutase. O princípio geral do primeiro método baseou-se na formação de metahemoglobina pelo nitrito de sódio, seguido da estimulação da via das pentoses pelo azul de metileno. Foram estudados 46 indivíduos adultos, sendo 23 do sexo masculino e 23 do feminino, não deficientes em glicose-6-fosfato desidrogenase (G6PD), com idades variando entre 20 e 30 anos. Os resultados revelaram que a redução da metahemoglobina pelo azul de metileno para sangue total, foram de 154.50 e 139.90 mg/min (p
- Subjects :
- Adult
Male
lcsh:Arctic medicine. Tropical medicine
lcsh:RC955-962
Riboflavin
Cystamine
Glucosephosphate Dehydrogenase
Methemoglobin
chemistry.chemical_compound
Sex Factors
hemic and lymphatic diseases
Humans
Glucose-6-phosphate dehydrogenase
Glutathione reductase
Sodium Nitrite
General Medicine
Molecular biology
Methylene Blue
Glucosephosphate Dehydrogenase Deficiency
Infectious Diseases
chemistry
Glutathione reductase activity
Female
Oxidation-Reduction
Methylene blue
Subjects
Details
- ISSN :
- 00364665 and 16789946
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Revista do Instituto de Medicina Tropical de São Paulo
- Accession number :
- edsair.doi.dedup.....3368d786a220511f200e9a5479cae6b6
- Full Text :
- https://doi.org/10.1590/s0036-46651988000500007