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A 23-year-old woman with Turner syndrome experienced a lack of efficacy during treatment for thoracoabdominal aortic dissection type B. Despite receiving esmolol, nicardipine, and fentanyl, she continued to experience persistent pain. Her medical therapy was adjusted, and she was eventually discharged in stable condition. One month later, a follow-up scan showed no change in her aortic dissection, and she continued with medical therapy in preparation for possible elective aortic repair. [Extracted from the article]

A 68-year-old woman with a history of mitochondrial myopathy was treated for atrial flutter with rapid ventricular response using metoprolol, digoxin, and esmolol. However, the treatment was not effective, and her condition persisted. Further examinations revealed a left atrial appendage thrombus, and she was subsequently treated with amiodarone for rhythm control. Her ejection fraction improved, but she developed cardiomyopathy due to tachycardia. She was eventually discharged in a stable condition and underwent further treatment one month later. [Extracted from the article]

A 48-year-old man experienced skin necrosis at the injection site while being treated with esmolol for non-ST-elevation myocardial infarction (NSTEMI). The man had a history of hypertension and NSTEMI and was admitted to the cardiac critical unit. After receiving peripheral IV esmolol injection for 24 hours, he developed pain, moderate edema, and bullae around the injection site. The man's condition worsened, resulting in necrosis after one week. It was determined that the skin necrosis was a result of esmolol treatment. [Extracted from the article]

B Author Information b An event is serious (based on the ICH definition) when the patient outcome is: * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important event In a case series, a 46-year-old woman was described, who exhibited lack of efficacy during treatment with phentolamine and esmolol for phaeochromocytoma multisystem crisis (PMC) [ I dosages not stated i ]. She experienced recurrent crises despite adequate administration of phentolamine and esmolol therapy, indicating lack of efficacy. She had coagulation disorder, renal failure and liver dysfunction, and she received blood transfusion and underwent haemodialysis. [Extracted from the article]

B Author Information b An event is serious (based on the ICH definition) when the patient outcome is: * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important event The female neonate [ I exact age not stated i ] exhibited lack of efficacy to esmolol, lidocaine and magnesium, while being treated for polymorphic ventricular tachycardia [ I not all routes and dosages stated i ]. Due to recurrent episodes of polymorphic ventricular tachycardia magnesium bolus, additional lidocaine bolus was given and esmolol 25 µg/kg/min and lidocaine 25 µg/kg/min was initiated. [Extracted from the article]

The infants received antiarrhythmic therapy with amiodarone 5 mg/kg and esmolol 250 µg/kg/min (1 infant) and amiodarone 5 mg/kg (2 infants) [ I routes not stated i ]. Despite receiving antiarrhythmic therapy with amiodarone or esmolol, a decrease in heart rate below 170 bpm was not observed in all three infants (lack of efficacy). [Extracted from the article]

Verapamil-sensitive idiopathic left ventricular tachycardia and concomitant atrioventricular nodal reentrant tachycardia. B Author Information b An event is serious (based on the ICH definition) when the patient outcome is: * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important event A 33-year-old man exhibited ineffectiveness with esmolol and metoprolol, while being treated for monomorphic ventricular tachycardia (VT). Then he was diagnosed with idiopathic left ventricular tachycardia along with atrioventricular nodal reentrant tachycardia successfully ablated using high-density electroanatomical mapping and an open-irrigation catheter. [Extracted from the article]

He received standard tetanus treatment, including unspecified sedatives and unspecified muscle relaxants, mechanical ventilation through tracheal intubation and nasal jejunal nutrition tubes, and the convulsions were controlled. Then, she was transferred to the ICU for standard tetanus treatment, including unspecified sedatives and unspecified muscle relaxants. B Author Information b An event is serious (based on the ICH definition) when the patient outcome is: * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important event In a retrospective study of 46 patients with tetanus treated from 1965 to 2020, two patients (a 67-year-old woman and a 34-year-old man) were described, who exhibited lack of efficacy with esmolol while being treated for tetanus [ I dosages not stated i ]. [Extracted from the article]

The article presents a case study of a 16-year-old boy who developed trigemino cardiac reflex (TCR) after receiving dimethyl sulfoxide, ethylene vinyl alcohol copolymer, esmolol and labetalol treatment for unruptured left cerebellar arteriovenous malformation (AVM). It mentions that the boy underwent cardiopulmonary resuscitation.

The article describes the case of iatrogenic reverse takotsubo cardiomyopathy that developed in a 47-year-old woman following administration of esmolol.

The article describes the case of a male neonate who developed failure of antiarrhythmic treatments with amiodarone, esmolol, digoxin, sotalol and flecainide for tachycardia and recurrent atrial flutter.

The article describes the case of a 25-year-old female patient who developed hypotension and pulseless electrical activity after being treated with metoprolol and esmolol.

The article presents a case study of a 30-year-old male patient who developed cardiomyopathy after he consumed labetalol, esmolol and metoprolol as part of his therapy after undergoing type-B aortic dissection.