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Your search keyword '"Castelijns, Jonas A."' showing total 16 results
Start Over Author "Castelijns, Jonas A." Journal radiology
16 results on '"Castelijns, Jonas A."'

1. MRI Features for Identifying MYCN-amplified RB1 Wild-type Retinoblastoma

Author

Jansen, Robin W., primary, de Bloeme, Christiaan M., additional, Cardoen, Liesbeth, additional, Göricke, Sophia, additional, van Elst, Sabien, additional, Jessen, Jaime Lyn, additional, Ramasubramanian, Aparna, additional, Skalet, Alison H., additional, Miller, Audra K., additional, Maeder, Philippe, additional, Uner, Ogul E., additional, Hubbard, G. Baker, additional, Grossniklaus, Hans, additional, Boldt, H. Culver, additional, Nichols, Kim E., additional, Brennan, Rachel C., additional, Sen, Saugata, additional, Sirin, Selma, additional, Brisse, Hervé J., additional, Galluzzi, Paolo, additional, Dommering, Charlotte J., additional, Castelijns, Jonas A., additional, van der Valk, Paul, additional, Boellaard, Ronald, additional, Dorsman, Josephine, additional, Moll, Annette C., additional, de Jong, Marcus C., additional, and de Graaf, Pim, additional

Published
2023
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2. Diagnostic Accuracy of Intraocular Tumor Size Measured with MR Imaging in the Prediction of Postlaminar Optic Nerve Invasion and Massive Choroidal Invasion of Retinoblastoma

Author

De Jong, Marcus C., van der Meer, Fenna J. S., Goricke, Sophia L., Brisse, Herve J., Galluzzi, Paolo, Maeder, Philippe, Sirin, Selma, De Francesco, Sonia, Sastre-Garau, Xavier, Metz, Klaus A., Cerase, Alfonso, Noij, Daniel P., van der Valk, Paul, Moll, Annette C., Castelijns, Jonas A., de Graaf, Pim, Radiology and nuclear medicine, Cardio-thoracic surgery, Pathology, Ophthalmology, EMGO - Quality of care, and CCA - Imaging

Subjects
Male, Pathology, medicine.medical_specialty, Retinal Neoplasms, Enucleation, Medizin, Intraocular Retinoblastoma, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Humans, Medicine, Neoplasm Invasiveness, Radiology, Nuclear Medicine and imaging, Retrospective Studies, medicine.diagnostic_test, Receiver operating characteristic, business.industry, Retinoblastoma, Choroid Neoplasms, Optic Nerve Neoplasms, Magnetic resonance imaging, medicine.disease, Magnetic Resonance Imaging, Confidence interval, 030221 ophthalmology & optometry, Optic nerve, Regression Analysis, Population study, Female, business, Nuclear medicine, Forecasting
Abstract

Purpose To assess the correlation of intraocular retinoblastoma tumor size measured with magnetic resonance (MR) imaging in the prediction of histopathologically determined metastatic risk factors (postlaminar optic nerve invasion and massive choroidal invasion). Materials and Methods The ethics committee approved this retrospective multicenter study with a waiver of informed consent. The study population included 370 consecutive patients with retinoblastoma (375 eyes) who underwent baseline MR imaging, followed by primary enucleation from 1993 through 2014. Tumor sizes (maximum diameter and volume) were measured independently by two observers and correlated with histopathologic risk factors. Receiver operating characteristic curves were used to analyze the diagnostic accuracy of tumor size, and areas under the curve were calculated. Logistic regression analysis was performed to evaluate potential confounders. Results Receiver operating characteristic analysis of volume and diameter, respectively, yielded areas under the curve of 0.77 (95% confidence interval [CI]: 0.70, 0.85; P < .0001) and 0.78 (95% CI: 0.71, 0.85; P < .0001) for postlaminar optic nerve invasion (n = 375) and 0.67 (95% CI: 0.57, 0.77; P = .0020) and 0.70 (95% CI: 0.59, 0.80; P = .0004) for massive choroidal tumor invasion (n = 219). For the detection of co-occurring massive choroidal invasion and postlaminar optic nerve invasion (n = 219), volume and diameter showed areas under the curve of 0.81 (95% CI: 0.70, 0.91; P = .0032) and 0.83 (95% CI: 0.73, 0.93; P = .0016), respectively. Conclusion Intraocular tumor size shows a strong association with postlaminar optic nerve invasion and a moderate association with massive choroidal invasion. These findings provide diagnostic accuracy measures at different size cutoff levels, which could potentially be useful in a clinical setting, especially within the scope of the increasing use of eye-salvage treatment strategies. (©) RSNA, 2015 Online supplemental material is available for this article.

Published
2016
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3. MR Imaging Features of Retinoblastoma: Association with Gene Expression Profiles

Author

Jansen, Robin W., primary, de Jong, Marcus C., additional, Kooi, Irsan E., additional, Sirin, Selma, additional, Göricke, Sophia, additional, Brisse, Hervé J., additional, Maeder, Philippe, additional, Galluzzi, Paolo, additional, van der Valk, Paul, additional, Cloos, Jacqueline, additional, Eekhout, Iris, additional, Castelijns, Jonas A., additional, Moll, Annette C., additional, Dorsman, Josephine C., additional, and de Graaf, Pim, additional

Published
2018
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7. Whole-Brain T1 Mapping in Multiple Sclerosis: Global Changes of Normal-appearing Gray and White Matter

Author

Vrenken, Hugo, primary, Geurts, Jeroen J. G., additional, Knol, Dirk L., additional, van Dijk, L. Noor, additional, Dattola, Vincenzo, additional, Jasperse, Bas, additional, van Schijndel, Ronald A., additional, Polman, Chris H., additional, Castelijns, Jonas A., additional, Barkhof, Frederik, additional, and Pouwels, Petra J. W., additional

Published
2006
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10. The Spinal Cord in Multiple Sclerosis: Relationship of High-Spatial-Resolution Quantitative MR Imaging Findings to Histopathologic Results

Author

Bot, Joseph C. J., primary, Blezer, Erwin L. A., additional, Kamphorst, Wouter, additional, Lycklama à Nijeholt, Geert J., additional, Ader, Herman J., additional, Castelijns, Jonas A., additional, Ig, Klaas Nicolay, additional, Bergers, Elisabeth, additional, Ravid, Rivka, additional, Polman, Chris, additional, and Barkhof, Frederik, additional

Published
2004
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12. MRI Features for Identifying MYCN-amplified RB1Wild-type Retinoblastoma

Author

Jansen, Robin W., Bloeme, Christiaan M. de, Cardoen, Liesbeth, Göricke, Sophia, Elst, Sabien van, Jessen, Jaime Lyn, Ramasubramanian, Aparna, Skalet, Alison H., Miller, Audra K., Maeder, Philippe, Uner, Ogul E., Hubbard, G. Baker, Grossniklaus, Hans, Boldt, H. Culver, Nichols, Kim E., Brennan, Rachel C., Sen, Saugata, Sirin, Selma, Brisse, Hervé J., Galluzzi, Paolo, Dommering, Charlotte J., Castelijns, Jonas A., Valk, Paul van der, Boellaard, Ronald, Dorsman, Josephine, Moll, Annette C., Jong, Marcus C. de, and Graaf, Pim de

Abstract

MYCN-amplified RB1wild-type retinoblastoma has distinct features compared with RB1pathogenic variant–driven retinoblastoma at MRI, including tumors in a peripheral (anterior) location with plaque or pleomorphic shape, irregular margins, tumor-retinal folding, and peritumoral blood.

Published
2023
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13. Differentiation of Multiple Sclerosis from Other Inflammatory Disorders and Cerebrovascular Disease: Value of Spinal MR Imaging

Author

Bot, Joost C. J., primary, Barkhof, Frederik, additional, à Nijeholt, Geert Lycklama, additional, van Schaardenburg, Dirkjan, additional, Voskuyl, Alexandre E., additional, Ader, Herman J., additional, Pijnenburg, Jolanda A. L., additional, Polman, Chris H., additional, Uitdehaag, Bernard M. J., additional, Vermeulen, Erik G. J., additional, and Castelijns, Jonas A., additional

Published
2002
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