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Start Over Author "Dhan Samuel" Journal open forum infectious diseases
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1. Detection of Vaccine-Induced Antibodies to Ebola Virus in Oral Fluid

Author

Teresa, Lambe, Tommy, Rampling, Dhan, Samuel, Georgina, Bowyer, Katie J, Ewer, Navin, Venkatraman, Matthew, Edmans, Steve, Dicks, Adrian V S, Hill, Richard S, Tedder, and Sarah C, Gilbert

Subjects
Ebola vaccine, antibodies, serology, Brief Reports, oral fluid
Abstract

Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875.

Published
2015

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