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Detection of Vaccine-Induced Antibodies to Ebola Virus in Oral Fluid

Authors :
Teresa, Lambe
Tommy, Rampling
Dhan, Samuel
Georgina, Bowyer
Katie J, Ewer
Navin, Venkatraman
Matthew, Edmans
Steve, Dicks
Adrian V S, Hill
Richard S, Tedder
Sarah C, Gilbert
Source :
Open Forum Infectious Diseases
Publication Year :
2015

Abstract

Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875.

Details

ISSN :
23288957
Volume :
3
Issue :
1
Database :
OpenAIRE
Journal :
Open forum infectious diseases
Accession number :
edsair.pmid..........d947bb411c726ab4229788f7753f3e5e