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Aim: Anxiety and depression are prevalent among patients with end stage renal failure. However, data concerning their role in the subsequent peritonitis and hospitalization was scarce. The aim of this study was to examine the prevalence of psychological problems in our Chinese peritoneal dialysis (PD) patients and its association with subsequent clinical outcome. Methods: This was a single-centre prospective cohort study. All patients newly started on PD between 1 September 2012 and 31 December 2014 were recruited. Hospital Anxiety Depression Scale was used to categorize the patients into high score group (HSG) and low score group (LSG). Higher score reflects higher emotional distress. Results: A total of 132 patients were recruited. Seventy-five patients (55%) were categorized as HSG. Higher overall peritonitis rate and Gram-positive organism associated peritonitis rate were observed in HSG (P = 0.012 and P = 0.016, respectively). The hospitalization rates in HSG and LSG were 1.20 episodes per patient-year and 1.05 episodes per patient-year respectively. Both high CCI (OR 1.33, 95% CI 1.10–1.62, P < 0.01) and HSG (OR 3.17, 95% CI 1.27–7.93, P = 0.01) were independent risk factors for PD peritonitis. Conclusion: Anxiety and depression were also common among Chinese PD patients. Those in HSG were more likely to develop PD peritonitis. These psychological symptoms deserved early detection. Further studies are needed to investigate whether intervention can improve the clinical outcome of these patients. [ABSTRACT FROM AUTHOR]

I Prevotella i peritonitis is rare in patients receiving continuous ambulatory peritoneal dialysis (CAPD).[1] We report the first case of the successful treatment of CAPD peritonitis together with intra-abdominal abscess formation due to I Prevotella i species and I Streptococcus anginosus i co-infection. They normally present infection with other bacteria and can cause periodontal infections, intra-abdominal infections, pneumonia, skin and soft tissue infections and gynaecological infections. However, first generation cephalosporins are generally ineffective because of cephalosporinase production.[2] I Streptococcus anginosus i group can cause invasive pyogenic infections while mixed infections with anaerobes can promote abscess formation.[3] Surgical drainage along with antibiotics therapy is often necessary in treating I S. anginosus i infections. [Extracted from the article]