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1 results on '"Lipids"'

1. TNF-a is not the cause of fatty liver disease in obese diabetic mice.

Author

Memon, Riaz A., Grunfeld, Carl, and Feingold, Kenneth R.

Subjects
*OBESITY, *LIPIDS, *PEOPLE with diabetes, *TUMOR necrosis factors
Abstract

Examines the role of metaformin treatment reverses fatty liver disease (FLD) in obese, leptin-deficient (ob/ob) mice by decreasing hepatic tumor necrosis factor(TNF)-α messenger RNA expression. Comparison of hepatic lipid content in ob/ob mice with or without TNF receptors; Occurrence of FLD in ob/ob mice in the absence of TNF action and TNF-induced insulin resistance.

Published
2001
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