Search

Your search keyword '"Hu, Zhibin"' showing total 22 results
Start Over Author "Hu, Zhibin" Journal nature genetics
22 results on '"Hu, Zhibin"'

1. Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations

Author

Wu, Chen, Wang, Zhaoming, Song, Xin, Feng, Xiao-Shan, Abnet, Christian C, He, Jie, Hu, Nan, Zuo, Xian-Bo, Tan, Wen, Zhan, Qimin, Hu, Zhibin, He, Zhonghu, Jia, Weihua, Zhou, Yifeng, Yu, Kai, Shu, Xiao-Ou, Yuan, Jian-Min, Zheng, Wei, Zhao, Xue-Ke, Gao, She-Gan, Yuan, Zhi-Qing, Zhou, Fu-You, Fan, Zong-Min, Cui, Ji-Li, Lin, Hong-Li, Han, Xue-Na, Li, Bei, Chen, Xi, Dawsey, Sanford M, Liao, Linda, Lee, Maxwell P, Ding, Ti, Qiao, You-Lin, Liu, Zhihua, Liu, Yu, Yu, Dianke, Chang, Jiang, Wei, Lixuan, Gao, Yu-Tang, Koh, Woon-Puay, Xiang, Yong-Bing, Tang, Ze-Zhong, Fan, Jin-Hu, Han, Jing-Jing, Zhou, Sheng-Li, Zhang, Peng, Zhang, Dong-Yun, Yuan, Yuan, Huang, Ying, Liu, Chunling, Zhai, Kan, Qiao, Yan, Jin, Guangfu, Guo, Chuanhai, Fu, Jianhua, Miao, Xiaoping, Lu, Changdong, Yang, Haijun, Wang, Chaoyu, Wheeler, William A, Gail, Mitchell, Yeager, Meredith, Yuenger, Jeff, Guo, Er-Tao, Li, Ai-Li, Zhang, Wei, Li, Xue-Min, Sun, Liang-Dan, Ma, Bao-Gen, Li, Yan, Tang, Sa, Peng, Xiu-Qing, Liu, Jing, Hutchinson, Amy, Jacobs, Kevin, Giffen, Carol, Burdette, Laurie, Fraumeni, Jr, Joseph F, Shen, Hongbing, Ke, Yang, Zeng, Yixin, Wu, Tangchun, Kraft, Peter, Chung, Charles C, Tucker, Margaret A, Hou, Zhi-Chao, Liu, Ya-Li, Hu, Yan-Long, Liu, Yu, Wang, Li, Yuan, Guo, Chen, Li-Sha, Liu, Xiao, Ma, Teng, Meng, Hui, Sun, Li, Li, Xin-Min, Li, Xiu-Min, Ku, Jian-Wei, Zhou, Ying-Fa, Yang, Liu-Qin, Wang, Zhou, Li, Yin, Qige, Qirenwang, Yang, Wen-Jun, Lei, Guang-Yan, Chen, Long-Qi, Li, En-Min, Yuan, Ling, Yue, Wen-Bin, Wang, Ran, Wang, Lu-Wen, Fan, Xue-Ping, Zhu, Fang-Heng, Zhao, Wei-Xing, Mao, Yi-Min, Zhang, Mei, Xing, Guo-Lan, Li, Ji-Lin, Han, Min, Ren, Jing-Li, Liu, Bin, Ren, Shu-Wei, Kong, Qing-Peng, Li, Feng, Sheyhidin, Ilyar, Wei, Wu, Zhang, Yan-Rui, Feng, Chang-Wei, Wang, Jin, Yang, Yu-Hua, Hao, Hong-Zhang, Bao, Qi-De, Liu, Bao-Chi, Wu, Ai-Qun, Xie, Dong, Yang, Wan-Cai, Wang, Liang, Zhao, Xiao-Hang, Chen, Shu-Qing, Hong, Jun-Yan, Zhang, Xue-Jun, Freedman, Neal D, Goldstein, Alisa M, Lin, Dongxin, Taylor, Philip R, Wang, Li-Dong, and Chanock, Stephen J

Published
2014
Full Text
View/download PDF

2. Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions

Author

Wu, Chen, Kraft, Peter, Zhai, Kan, Chang, Jiang, Wang, Zhaoming, Li, Yun, Hu, Zhibin, He, Zhonghu, Jia, Weihua, Abnet, Christian C, Liang, Liming, Hu, Nan, Miao, Xiaoping, Zhou, Yifeng, Liu, Zhihua, Zhan, Qimin, Liu, Yu, Qiao, Yan, Zhou, Yuling, Jin, Guangfu, Guo, Chuanhai, Lu, Changdong, Yang, Haijun, Fu, Jianhua, Yu, Dianke, Freedman, Neal D, Ding, Ti, Tan, Wen, Goldstein, Alisa M, Wu, Tangchun, Shen, Hongbing, Ke, Yang, Zeng, Yixin, Chanock, Stephen J, Taylor, Philip R, and Lin, Dongxin

Published
2012
Full Text
View/download PDF

3. Corrigendum: Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions

Author

Wu, Chen, Kraft, Peter, Zhai, Kan, Chang, Jiang, Wang, Zhaoming, Li, Yun, Hu, Zhibin, He, Zhonghu, Jia, Weihua, Abnet, Christian C, Liang, Liming, Hu, Nan, Miao, Xiaoping, Zhou, Yifeng, Liu, Zhihua, Zhan, Qimin, Liu, Yu, Qiao, Yan, Zhou, Yuling, Jin, Guangfu, Guo, Chuanhai, Lu, Changdong, Yang, Haijun, Fu, Jianhua, Yu, Dianke, Freedman, Neal D, Ding, Ti, Tan, Wen, Goldstein, Alisa M, Wu, Tangchun, Shen, Hongbing, Ke, Yang, Zeng, Yixin, Chanock, Stephen J, Taylor, Philip R, and Lin, Dongxin

Published
2014
Full Text
View/download PDF

4. Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population

Author

Wei, Qingyi, primary, Yu, Dianke, additional, Liu, Mingbo, additional, Wang, Mengyun, additional, Zhao, Miaoqing, additional, Liu, Ming, additional, Jia, Weihua, additional, Ma, Hongxia, additional, Fang, Jugao, additional, Xu, Wei, additional, Chen, Kexing, additional, Xu, Zhengang, additional, Wang, Jialing, additional, Tian, Linli, additional, Yuan, Hua, additional, Chang, Jiang, additional, Hu, Zhibin, additional, Wei, Lixun, additional, Huang, Ying, additional, Han, Yaling, additional, Liu, Jie, additional, Han, Demin, additional, Shen, Hongbing, additional, Yang, Shiming, additional, Zheng, Hong, additional, Ji, Qinghai, additional, Li, Duanshu, additional, Tan, Wen, additional, Wu, Chen, additional, and Lin, Dongxin, additional

Published
2014
Full Text
View/download PDF

5. New loci associated with chronic hepatitis B virus infection in Han Chinese

Author

Hu, Zhibin, primary, Liu, Yao, additional, Zhai, Xiangjun, additional, Dai, Juncheng, additional, Jin, Guangfu, additional, Wang, Li, additional, Zhu, Liguo, additional, Yang, Yuan, additional, Liu, Jibin, additional, Chu, Minjie, additional, Wen, Juan, additional, Xie, Kaipeng, additional, Du, Guoming, additional, Wang, Qungang, additional, Zhou, Yuchun, additional, Cao, Minquan, additional, Liu, Li, additional, He, Yisha, additional, Wang, Ying, additional, Zhou, Gangqiao, additional, Jia, Weihua, additional, Lu, Jiachun, additional, Li, Shengping, additional, Liu, Jianjun, additional, Yang, Haitao, additional, Shi, Yongyong, additional, Zhou, Weiping, additional, and Shen, Hongbing, additional

Published
2013
Full Text
View/download PDF

6. A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12

Author

Shi, Yongyong, primary, Li, Li, additional, Hu, Zhibin, additional, Li, Shuang, additional, Wang, Shixuan, additional, Liu, Jihong, additional, Wu, Chen, additional, He, Lin, additional, Zhou, Jianfeng, additional, Li, Zhiqiang, additional, Hu, Ting, additional, Chen, Yile, additional, Jia, Yao, additional, Wang, Shaoshuai, additional, Wu, Li, additional, Cheng, Xiaodong, additional, Yang, Zhijun, additional, Yang, Ru, additional, Li, Xiong, additional, Huang, Kecheng, additional, Zhang, Qinghua, additional, Zhou, Hang, additional, Tang, Fangxu, additional, Chen, Zhilan, additional, Shen, Jian, additional, Jiang, Jie, additional, Ding, Hu, additional, Xing, Hui, additional, Zhang, Shulan, additional, Qu, Pengpeng, additional, Song, Xiaojie, additional, Lin, Zhongqiu, additional, Deng, Dongrui, additional, Xi, Ling, additional, Lv, Weiguo, additional, Han, Xiaobing, additional, Tao, Guangshi, additional, Yan, Lixing, additional, Han, Zhedong, additional, Li, Zhuang, additional, Miao, Xiaoping, additional, Pan, Shandong, additional, Shen, Yuanming, additional, Wang, Hui, additional, Liu, Dan, additional, Gong, Ee, additional, Li, Zheng, additional, Zhou, Limei, additional, Luan, Xiaomei, additional, Wang, Chuping, additional, Song, Qian, additional, Wu, Sufang, additional, Xu, Hongbin, additional, Shen, Jiawei, additional, Qiang, Fulin, additional, Ma, Gang, additional, Liu, Li, additional, Chen, Xiaojun, additional, Liu, Jibin, additional, Wu, Jiangping, additional, Shen, Yan, additional, Wen, Yang, additional, Chu, Minjie, additional, Yu, Jiang, additional, Hu, Xiaoxia, additional, Fan, Yujuan, additional, He, Hongying, additional, Jiang, Yanming, additional, Lei, Zhiying, additional, Liu, Cui, additional, Chen, Jianhua, additional, Zhang, Yuan, additional, Yi, Cunjian, additional, Chen, Shuangyun, additional, Li, Wenjin, additional, Wang, Daowen, additional, Wang, Zehua, additional, Di, Wen, additional, Shen, Keng, additional, Lin, Dongxin, additional, Shen, Hongbing, additional, Feng, Youji, additional, Xie, Xing, additional, and Ma, Ding, additional

Published
2013
Full Text
View/download PDF

7. A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations

Author

Hu, Zhibin, primary, Shi, Yongyong, additional, Mo, Xuming, additional, Xu, Jing, additional, Zhao, Bijun, additional, Lin, Yuan, additional, Yang, Shiwei, additional, Xu, Zhengfeng, additional, Dai, Juncheng, additional, Pan, Shandong, additional, Da, Min, additional, Wang, Xiaowei, additional, Qian, Bo, additional, Wen, Yang, additional, Wen, Juan, additional, Xing, Jinliang, additional, Guo, Xuejiang, additional, Xia, Yankai, additional, Ma, Hongxia, additional, Jin, Guangfu, additional, Yu, Shiqiang, additional, Liu, Jiayin, additional, Zhou, Zuomin, additional, Wang, Xinru, additional, Chen, Yijiang, additional, Sha, Jiahao, additional, and Shen, Hongbing, additional

Published
2013
Full Text
View/download PDF

8. Genome-wide association study identifies common variants in SLC39A6 associated with length of survival in esophageal squamous-cell carcinoma

Author

Wu, Chen, primary, Li, Dong, additional, Jia, Weihua, additional, Hu, Zhibin, additional, Zhou, Yifeng, additional, Yu, Dianke, additional, Tong, Tong, additional, Wang, Mingrong, additional, Lin, Dongmei, additional, Qiao, Yan, additional, Zhou, Yuling, additional, Chang, Jiang, additional, Zhai, Kan, additional, Wang, Menghan, additional, Wei, Lixuan, additional, Tan, Wen, additional, Shen, Hongbing, additional, Zeng, Yixin, additional, and Lin, Dongxin, additional

Published
2013
Full Text
View/download PDF

9. Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus–related hepatocellular carcinoma

Author

Jiang, De-Ke, primary, Sun, Jielin, additional, Cao, Guangwen, additional, Liu, Yao, additional, Lin, Dongxin, additional, Gao, Yu-Zhen, additional, Ren, Wei-Hua, additional, Long, Xi-Dai, additional, Zhang, Hongxing, additional, Ma, Xiao-Pin, additional, Wang, Zhong, additional, Jiang, Wei, additional, Chen, Tao-Yang, additional, Gao, Yong, additional, Sun, Liang-Dan, additional, Long, Ji-Rong, additional, Huang, Hui-Xing, additional, Wang, Dan, additional, Yu, Hongjie, additional, Zhang, Pengyin, additional, Tang, Li-Sha, additional, Peng, Bo, additional, Cai, Hao, additional, Liu, Ting-Ting, additional, Zhou, Ping, additional, Liu, Fang, additional, Lin, Xiaoling, additional, Tao, Sha, additional, Wan, Bo, additional, Sai-Yin, He-Xi Ge, additional, Qin, Lun-Xiu, additional, Yin, Jianhua, additional, Liu, Li, additional, Wu, Chen, additional, Pei, Yan, additional, Zhou, Yuan-Feng, additional, Zhai, Yun, additional, Lu, Pei-Xin, additional, Tan, Aihua, additional, Zuo, Xian-Bo, additional, Fan, Jia, additional, Chang, Jiang, additional, Gu, Xiaoli, additional, Wang, Neng-Jin, additional, Li, Yang, additional, Liu, Yin-Kun, additional, Zhai, Kan, additional, Zhang, Hongwei, additional, Hu, Zhibin, additional, Liu, Jun, additional, Yi, Qing, additional, Xiang, Yongbing, additional, Shi, Rong, additional, Ding, Qiang, additional, Zheng, Wei, additional, Shu, Xiao-Ou, additional, Mo, Zengnan, additional, Shugart, Yin Yao, additional, Zhang, Xue-Jun, additional, Zhou, Gangqiao, additional, Shen, Hongbing, additional, Zheng, S Lilly, additional, Xu, Jianfeng, additional, and Yu, Long, additional

Published
2012
Full Text
View/download PDF

10. Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

Author

Lan, Qing, primary, Hsiung, Chao A, additional, Matsuo, Keitaro, additional, Hong, Yun-Chul, additional, Seow, Adeline, additional, Wang, Zhaoming, additional, Hosgood, H Dean, additional, Chen, Kexin, additional, Wang, Jiu-Cun, additional, Chatterjee, Nilanjan, additional, Hu, Wei, additional, Wong, Maria Pik, additional, Zheng, Wei, additional, Caporaso, Neil, additional, Park, Jae Yong, additional, Chen, Chien-Jen, additional, Kim, Yeul Hong, additional, Kim, Young Tae, additional, Landi, Maria Teresa, additional, Shen, Hongbing, additional, Lawrence, Charles, additional, Burdett, Laurie, additional, Yeager, Meredith, additional, Yuenger, Jeffrey, additional, Jacobs, Kevin B, additional, Chang, I-Shou, additional, Mitsudomi, Tetsuya, additional, Kim, Hee Nam, additional, Chang, Gee-Chen, additional, Bassig, Bryan A, additional, Tucker, Margaret, additional, Wei, Fusheng, additional, Yin, Zhihua, additional, Wu, Chen, additional, An, She-Juan, additional, Qian, Biyun, additional, Lee, Victor Ho Fun, additional, Lu, Daru, additional, Liu, Jianjun, additional, Jeon, Hyo-Sung, additional, Hsiao, Chin-Fu, additional, Sung, Jae Sook, additional, Kim, Jin Hee, additional, Gao, Yu-Tang, additional, Tsai, Ying-Huang, additional, Jung, Yoo Jin, additional, Guo, Huan, additional, Hu, Zhibin, additional, Hutchinson, Amy, additional, Wang, Wen-Chang, additional, Klein, Robert, additional, Chung, Charles C, additional, Oh, In-Jae, additional, Chen, Kuan-Yu, additional, Berndt, Sonja I, additional, He, Xingzhou, additional, Wu, Wei, additional, Chang, Jiang, additional, Zhang, Xu-Chao, additional, Huang, Ming-Shyan, additional, Zheng, Hong, additional, Wang, Junwen, additional, Zhao, Xueying, additional, Li, Yuqing, additional, Choi, Jin Eun, additional, Su, Wu-Chou, additional, Park, Kyong Hwa, additional, Sung, Sook Whan, additional, Shu, Xiao-Ou, additional, Chen, Yuh-Min, additional, Liu, Li, additional, Kang, Chang Hyun, additional, Hu, Lingmin, additional, Chen, Chung-Hsing, additional, Pao, William, additional, Kim, Young-Chul, additional, Yang, Tsung-Ying, additional, Xu, Jun, additional, Guan, Peng, additional, Tan, Wen, additional, Su, Jian, additional, Wang, Chih-Liang, additional, Li, Haixin, additional, Sihoe, Alan Dart Loon, additional, Zhao, Zhenhong, additional, Chen, Ying, additional, Choi, Yi Young, additional, Hung, Jen-Yu, additional, Kim, Jun Suk, additional, Yoon, Ho-Il, additional, Cai, Qiuyin, additional, Lin, Chien-Chung, additional, Park, In Kyu, additional, Xu, Ping, additional, Dong, Jing, additional, Kim, Christopher, additional, He, Qincheng, additional, Perng, Reury-Perng, additional, Kohno, Takashi, additional, Kweon, Sun-Seog, additional, Chen, Chih-Yi, additional, Vermeulen, Roel, additional, Wu, Junjie, additional, Lim, Wei-Yen, additional, Chen, Kun-Chieh, additional, Chow, Wong-Ho, additional, Ji, Bu-Tian, additional, Chan, John K C, additional, Chu, Minjie, additional, Li, Yao-Jen, additional, Yokota, Jun, additional, Li, Jihua, additional, Chen, Hongyan, additional, Xiang, Yong-Bing, additional, Yu, Chong-Jen, additional, Kunitoh, Hideo, additional, Wu, Guoping, additional, Jin, Li, additional, Lo, Yen-Li, additional, Shiraishi, Kouya, additional, Chen, Ying-Hsiang, additional, Lin, Hsien-Chih, additional, Wu, Tangchun, additional, Wu, Yi-Long, additional, Yang, Pan-Chyr, additional, Zhou, Baosen, additional, Shin, Min-Ho, additional, Fraumeni, Joseph F, additional, Lin, Dongxin, additional, Chanock, Stephen J, additional, and Rothman, Nathaniel, additional

Published
2012
Full Text
View/download PDF

11. Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4

Author

Xu, Jianfeng, primary, Mo, Zengnan, additional, Ye, Dingwei, additional, Wang, Meilin, additional, Liu, Fang, additional, Jin, Guangfu, additional, Xu, Chuanliang, additional, Wang, Xiang, additional, Shao, Qiang, additional, Chen, Zhiwen, additional, Tao, Zhihua, additional, Qi, Jun, additional, Zhou, Fangjian, additional, Wang, Zhong, additional, Fu, Yaowen, additional, He, Dalin, additional, Wei, Qiang, additional, Guo, Jianming, additional, Wu, Denglong, additional, Gao, Xin, additional, Yuan, Jianlin, additional, Wang, Gongxian, additional, Xu, Yong, additional, Wang, Guozeng, additional, Yao, Haijun, additional, Dong, Pei, additional, Jiao, Yang, additional, Shen, Mo, additional, Yang, Jin, additional, Ou-Yang, Jun, additional, Jiang, Haowen, additional, Zhu, Yao, additional, Ren, Shancheng, additional, Zhang, Zhengdong, additional, Yin, Changjun, additional, Gao, Xu, additional, Dai, Bo, additional, Hu, Zhibin, additional, Yang, Yajun, additional, Wu, Qijun, additional, Chen, Hongyan, additional, Peng, Peng, additional, Zheng, Ying, additional, Zheng, Xiaodong, additional, Xiang, Yongbing, additional, Long, Jirong, additional, Gong, Jian, additional, Na, Rong, additional, Lin, Xiaoling, additional, Yu, Hongjie, additional, Tao, Sha, additional, Feng, Junjie, additional, Sun, Jishan, additional, Liu, Wennuan, additional, Hsing, Ann, additional, Rao, Jianyu, additional, Ding, Qiang, additional, Wiklund, Fredirik, additional, Gronberg, Henrik, additional, Shu, Xiao-Ou, additional, Zheng, Wei, additional, Shen, Hongbing, additional, Jin, Li, additional, Shi, Rong, additional, Lu, Daru, additional, Zhang, Xuejun, additional, Sun, Jielin, additional, Zheng, S Lilly, additional, and Sun, Yinghao, additional

Published
2012
Full Text
View/download PDF

12. Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

Author

Dong, Jing, primary, Hu, Zhibin, additional, Wu, Chen, additional, Guo, Huan, additional, Zhou, Baosen, additional, Lv, Jiachun, additional, Lu, Daru, additional, Chen, Kexin, additional, Shi, Yongyong, additional, Chu, Minjie, additional, Wang, Cheng, additional, Zhang, Ruyang, additional, Dai, Juncheng, additional, Jiang, Yue, additional, Cao, Songyu, additional, Qin, Zhenzhen, additional, Yu, Dianke, additional, Ma, Hongxia, additional, Jin, Guangfu, additional, Gong, Jianhang, additional, Sun, Chongqi, additional, Zhao, Xueying, additional, Yin, Zhihua, additional, Yang, Lei, additional, Li, Zhiqiang, additional, Deng, Qifei, additional, Wang, Jiucun, additional, Wu, Wei, additional, Zheng, Hong, additional, Zhou, Guoquan, additional, Chen, Hongyan, additional, Guan, Peng, additional, Peng, Zhihang, additional, Chen, Yijiang, additional, Shu, Yongqian, additional, Xu, Lin, additional, Liu, Xiangyang, additional, Liu, Li, additional, Xu, Pin, additional, Han, Baohui, additional, Bai, Chunxue, additional, Zhao, Yuxia, additional, Zhang, Haibo, additional, Yan, Ying, additional, Amos, Christopher I, additional, Chen, Feng, additional, Tan, Wen, additional, Jin, Li, additional, Wu, Tangchun, additional, Lin, Dongxin, additional, and Shen, Hongbing, additional

Published
2012
Full Text
View/download PDF

13. Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

Author

McKay, James D, Hung, Rayjean J, Han, Younghun, Zong, Xuchen, Carreras-Torres, Robert, Christiani, David C, Caporaso, Neil E, Johansson, Mattias, Xiao, Xiangjun, Li, Yafang, Byun, Jinyoung, Dunning, Alison, Pooley, Karen A, Qian, David C, Ji, Xuemei, Liu, Geoffrey, Timofeeva, Maria N, Bojesen, Stig E, Wu, Xifeng, Le Marchand, Loic, Albanes, Demetrios, Bickeböller, Heike, Aldrich, Melinda C, Bush, William S, Tardon, Adonina, Rennert, Gad, Teare, M Dawn, Field, John K, Kiemeney, Lambertus A, Lazarus, Philip, Haugen, Aage, Lam, Stephen, Schabath, Matthew B, Andrew, Angeline S, Shen, Hongbing, Hong, Yun-Chul, Yuan, Jian-Min, Bertazzi, Pier Alberto, Pesatori, Angela C, Ye, Yuanqing, Diao, Nancy, Su, Li, Zhang, Ruyang, Brhane, Yonathan, Leighl, Natasha, Johansen, Jakob S, Mellemgaard, Anders, Saliba, Walid, Haiman, Christopher A, Wilkens, Lynne R, Fernandez-Somoano, Ana, Fernandez-Tardon, Guillermo, van der Heijden, Henricus F M, Kim, Jin Hee, Dai, Juncheng, Hu, Zhibin, Davies, Michael P A, Marcus, Michael W, Brunnström, Hans, Manjer, Jonas, Melander, Olle, Muller, David C, Overvad, Kim, Trichopoulou, Antonia, Tumino, Rosario, Doherty, Jennifer A, Barnett, Matt P, Chen, Chu, Goodman, Gary E, Cox, Angela, Taylor, Fiona, Woll, Penella, Brüske, Irene, Wichmann, H-Erich, Manz, Judith, Muley, Thomas R, Risch, Angela, Rosenberger, Albert, Grankvist, Kjell, Johansson, Mikael, Shepherd, Frances A, Tsao, Ming-Sound, Arnold, Susanne M, Haura, Eric B, Bolca, Ciprian, Holcatova, Ivana, Janout, Vladimir, Kontic, Milica, Lissowska, Jolanta, Mukeria, Anush, Ognjanovic, Simona, Orlowski, Tadeusz M, Scelo, Ghislaine, Swiatkowska, Beata, Zaridze, David, Bakke, Per, Skaug, Vidar, Zienolddiny, Shanbeh, Duell, Eric J, Butler, Lesley M, Koh, Woon-Puay, Gao, Yu-Tang, Houlston, Richard S, McLaughlin, John, Stevens, Victoria L, Joubert, Philippe, Lamontagne, Maxime, Nickle, David C, Obeidat, Ma'en, Timens, Wim, Zhu, Bin, Song, Lei, Kachuri, Linda, Artigas, María Soler, Tobin, Martin D, Wain, Louise V, Rafnar, Thorunn, Thorgeirsson, Thorgeir E, Reginsson, Gunnar W, Stefansson, Kari, Hancock, Dana B, Bierut, Laura J, Spitz, Margaret R, Gaddis, Nathan C, Lutz, Sharon M, Gu, Fangyi, Johnson, Eric O, Kamal, Ahsan, Pikielny, Claudio, Zhu, Dakai, Lindströem, Sara, Jiang, Xia, Tyndale, Rachel F, Chenevix-Trench, Georgia, Beesley, Jonathan, Bossé, Yohan, Chanock, Stephen, Brennan, Paul, Landi, Maria Teresa, and Amos, Christopher I

Abstract

Although several lung cancer susceptibility loci have been identified, much of the heritability for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European descent were genotyped on the OncoArray and combined with existing data for an aggregated genome-wide association study (GWAS) analysis of lung cancer in 29,266 cases and 56,450 controls. We identified 18 susceptibility loci achieving genome-wide significance, including 10 new loci. The new loci highlight the striking heterogeneity in genetic susceptibility across the histological subtypes of lung cancer, with four loci associated with lung cancer overall and six loci associated with lung adenocarcinoma. Gene expression quantitative trait locus (eQTL) analysis in 1,425 normal lung tissue samples highlights RNASET2, SECISBP2L and NRG1 as candidate genes. Other loci include genes such as a cholinergic nicotinic receptor, CHRNA2, and the telomere-related genes OFBC1 and RTEL1. Further exploration of the target genes will continue to provide new insights into the etiology of lung cancer.

Published
2017
Full Text
View/download PDF

14. A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia

Author

Hu, Zhibin, primary, Xia, Yankai, additional, Guo, Xuejiang, additional, Dai, Juncheng, additional, Li, HongGang, additional, Hu, Hongliang, additional, Jiang, Yue, additional, Lu, Feng, additional, Wu, Yibo, additional, Yang, Xiaoyu, additional, Li, Huizhang, additional, Yao, Bing, additional, Lu, Chuncheng, additional, Xiong, Chenliang, additional, Li, Zheng, additional, Gui, Yaoting, additional, Liu, Jiayin, additional, Zhou, Zuomin, additional, Shen, Hongbing, additional, Wang, Xinru, additional, and Sha, Jiahao, additional

Published
2011
Full Text
View/download PDF

15. Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations

Author

Wu, Chen, primary, Miao, Xiaoping, additional, Huang, Liming, additional, Che, Xu, additional, Jiang, Guoliang, additional, Yu, Dianke, additional, Yang, Xianghong, additional, Cao, Guangwen, additional, Hu, Zhibin, additional, Zhou, Yongjian, additional, Zuo, Chaohui, additional, Wang, Chunyou, additional, Zhang, Xianghong, additional, Zhou, Yifeng, additional, Yu, Xianjun, additional, Dai, Wanjin, additional, Li, Zhaoshen, additional, Shen, Hongbing, additional, Liu, Luming, additional, Chen, Yanling, additional, Zhang, Sheng, additional, Wang, Xiaoqi, additional, Zhai, Kan, additional, Chang, Jiang, additional, Liu, Yu, additional, Sun, Menghong, additional, Cao, Wei, additional, Gao, Jun, additional, Ma, Ying, additional, Zheng, Xiongwei, additional, Cheung, Siu Tim, additional, Jia, Yongfeng, additional, Xu, Jian, additional, Tan, Wen, additional, Zhao, Ping, additional, Wu, Tangchun, additional, Wang, Chengfeng, additional, and Lin, Dongxin, additional

Published
2011
Full Text
View/download PDF

16. A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1

Author

Shi, Yongyong, primary, Hu, Zhibin, additional, Wu, Chen, additional, Dai, Juncheng, additional, Li, Huizhang, additional, Dong, Jing, additional, Wang, Meilin, additional, Miao, Xiaoping, additional, Zhou, Yifeng, additional, Lu, Feng, additional, Zhang, Hanze, additional, Hu, Lingmin, additional, Jiang, Yue, additional, Li, Zhiqiang, additional, Chu, Minjie, additional, Ma, Hongxia, additional, Chen, Jiaping, additional, Jin, Guangfu, additional, Tan, Wen, additional, Wu, Tangchun, additional, Zhang, Zhengdong, additional, Lin, Dongxin, additional, and Shen, Hongbing, additional

Published
2011
Full Text
View/download PDF

17. A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese

Author

Hu, Zhibin, primary, Wu, Chen, additional, Shi, Yongyong, additional, Guo, Huan, additional, Zhao, Xueying, additional, Yin, Zhihua, additional, Yang, Lei, additional, Dai, Juncheng, additional, Hu, Lingmin, additional, Tan, Wen, additional, Li, Zhiqiang, additional, Deng, Qifei, additional, Wang, Jiucun, additional, Wu, Wei, additional, Jin, Guangfu, additional, Jiang, Yue, additional, Yu, Dianke, additional, Zhou, Guoquan, additional, Chen, Hongyan, additional, Guan, Peng, additional, Chen, Yijiang, additional, Shu, Yongqian, additional, Xu, Lin, additional, Liu, Xiangyang, additional, Liu, Li, additional, Xu, Ping, additional, Han, Baohui, additional, Bai, Chunxue, additional, Zhao, Yuxia, additional, Zhang, Haibo, additional, Yan, Ying, additional, Ma, Hongxia, additional, Chen, Jiaping, additional, Chu, Mingjie, additional, Lu, Feng, additional, Zhang, Zhengdong, additional, Chen, Feng, additional, Wang, Xinru, additional, Jin, Li, additional, Lu, Jiachun, additional, Zhou, Baosen, additional, Lu, Daru, additional, Wu, Tangchun, additional, Lin, Dongxin, additional, and Shen, Hongbing, additional

Published
2011
Full Text
View/download PDF

18. Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations

Author

Wu, Chen, primary, Hu, Zhibin, additional, He, Zhonghu, additional, Jia, Weihua, additional, Wang, Feng, additional, Zhou, Yifeng, additional, Liu, Zhihua, additional, Zhan, Qimin, additional, Liu, Yu, additional, Yu, Dianke, additional, Zhai, Kan, additional, Chang, Jiang, additional, Qiao, Yan, additional, Jin, Guangfu, additional, Liu, Zhe, additional, Shen, Yuanyuan, additional, Guo, Chuanhai, additional, Fu, Jianhua, additional, Miao, Xiaoping, additional, Tan, Wen, additional, Shen, Hongbing, additional, Ke, Yang, additional, Zeng, Yixin, additional, Wu, Tangchun, additional, and Lin, Dongxin, additional

Published
2011
Full Text
View/download PDF

19. Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers

Author

Zhang, Hongxing, primary, Zhai, Yun, additional, Hu, Zhibin, additional, Wu, Chen, additional, Qian, Ji, additional, Jia, Weihua, additional, Ma, Fuchao, additional, Huang, Wenfeng, additional, Yu, Lixia, additional, Yue, Wei, additional, Wang, Zhifu, additional, Li, Peiyao, additional, Zhang, Yang, additional, Liang, Renxiang, additional, Wei, Zhongliang, additional, Cui, Ying, additional, Xie, Weimin, additional, Cai, Mi, additional, Yu, Xinsen, additional, Yuan, Yunfei, additional, Xia, Xia, additional, Zhang, Xiumei, additional, Yang, Hao, additional, Qiu, Wei, additional, Yang, Jingmin, additional, Gong, Feng, additional, Chen, Minshan, additional, Shen, Hongbing, additional, Lin, Dongxin, additional, Zeng, Yi-Xin, additional, He, Fuchu, additional, and Zhou, Gangqiao, additional

Published
2010
Full Text
View/download PDF

20. A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.

Author

Hu, Zhibin, Xia, Yankai, Guo, Xuejiang, Dai, Juncheng, Li, HongGang, Hu, Hongliang, Jiang, Yue, Lu, Feng, Wu, Yibo, Yang, Xiaoyu, Li, Huizhang, Yao, Bing, Lu, Chuncheng, Xiong, Chenliang, Li, Zheng, Gui, Yaoting, Liu, Jiayin, Zhou, Zuomin, Shen, Hongbing, and Wang, Xinru

Subjects
*MALE infertility, *MALE reproductive organ diseases, *HUMAN genetic variation, *CHINESE people, *PLOIDY
Abstract

Non-obstructive azoospermia (NOA) is one of the most severe forms of male infertility. Its pathophysiology is largely unknown, and few genetic influences have been defined. To identify common variants contributing to NOA in Han Chinese men, we performed a three-stage genome-wide association study of 2,927 individuals with NOA and 5,734 controls. The combined analyses identified significant (P < 5.0 × 10?8) associations between NOA risk and common variants near PRMT6 (rs12097821 at 1p13.3: odds ratio (OR) = 1.25, P = 5.7 × 10?10), PEX10 (rs2477686 at 1p36.32: OR = 1.39, P = 5.7 × 10?12) and SOX5 (rs10842262 at 12p12.1: OR = 1.23, P = 2.3 × 10?9). These findings implicate genetic variants at 1p13.3, 1p36.32 and 12p12.1 in the etiology of NOA in Han Chinese men. [ABSTRACT FROM AUTHOR]

Published
2012
Full Text
View/download PDF

21. Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations.

Author

Wu, Chen, Miao, Xiaoping, Huang, Liming, Che, Xu, Jiang, Guoliang, Yu, Dianke, Yang, Xianghong, Cao, Guangwen, Hu, Zhibin, Zhou, Yongjian, Zuo, Chaohui, Wang, Chunyou, Zhang, Xianghong, Zhou, Yifeng, Yu, Xianjun, Dai, Wanjin, Li, Zhaoshen, Shen, Hongbing, Liu, Luming, and Chen, Yanling

Subjects
CANCER patients, PANCREATIC cancer, CHINESE people, DISEASE susceptibility, POLYCYSTIC kidney disease, CHROMOSOMES, DISEASES
Abstract

Pancreatic cancer has the lowest survival rate among human cancers, and there are no effective markers for its screening and early diagnosis. To identify genetic susceptibility markers for this cancer, we carried out a genome-wide association study on 981 individuals with pancreatic cancer (cases) and 1,991 cancer-free controls of Chinese descent using 666,141 autosomal SNPs. Promising associations were replicated in an additional 2,603 pancreatic cancer cases and 2,877 controls recruited from 25 hospitals in 16 provinces or cities in China. We identified five new susceptibility loci at chromosomes 21q21.3, 5p13.1, 21q22.3, 22q13.32 and 10q26.11 (P = 2.24 × 10?13 to P = 4.18 × 10?10) in addition to 13q22.1 previously reported in populations of European ancestry. These results advance our understanding of the development of pancreatic cancer and highlight potential targets for the prevention or treatment of this cancer. [ABSTRACT FROM AUTHOR]

Published
2012
Full Text
View/download PDF

22. Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma.

Author

Jiang DK, Sun J, Cao G, Liu Y, Lin D, Gao YZ, Ren WH, Long XD, Zhang H, Ma XP, Wang Z, Jiang W, Chen TY, Gao Y, Sun LD, Long JR, Huang HX, Wang D, Yu H, Zhang P, Tang LS, Peng B, Cai H, Liu TT, Zhou P, Liu F, Lin X, Tao S, Wan B, Sai-Yin HX, Qin LX, Yin J, Liu L, Wu C, Pei Y, Zhou YF, Zhai Y, Lu PX, Tan A, Zuo XB, Fan J, Chang J, Gu X, Wang NJ, Li Y, Liu YK, Zhai K, Zhang H, Hu Z, Liu J, Yi Q, Xiang Y, Shi R, Ding Q, Zheng W, Shu XO, Mo Z, Shugart YY, Zhang XJ, Zhou G, Shen H, Zheng SL, Xu J, and Yu L

Subjects
Carcinoma, Hepatocellular virology, Gene Expression, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, Hepatitis B virology, Hepatitis B virus genetics, Humans, Liver Neoplasms virology, Polymorphism, Single Nucleotide, Carcinoma, Hepatocellular complications, Carcinoma, Hepatocellular genetics, HLA-DQ Antigens genetics, Hepatitis B complications, Liver Neoplasms complications, Liver Neoplasms genetics, STAT4 Transcription Factor genetics
Abstract

To identify genetic susceptibility loci for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) in the Chinese population, we carried out a genome-wide association study (GWAS) in 2,514 chronic HBV carriers (1,161 HCC cases and 1,353 controls) followed by a 2-stage validation among 6 independent populations of chronic HBV carriers (4,319 cases and 4,966 controls). The joint analyses showed that HCC risk was significantly associated with two independent loci: rs7574865 at STAT4, P(meta) = 2.48 × 10(-10), odds ratio (OR) = 1.21; and rs9275319 at HLA-DQ, P(meta) = 2.72 × 10(-17), OR = 1.49. The risk allele G at rs7574865 was significantly associated with lower mRNA levels of STAT4 in both the HCC tissues and nontumor tissues of 155 individuals with HBV-related HCC (P(trend) = 0.0008 and 0.0002, respectively). We also found significantly lower mRNA expression of STAT4 in HCC tumor tissues compared with paired adjacent nontumor tissues (P = 2.33 × 10(-14)).

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results