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2. Persistence pays off: developing AIDS vaccines has been a frustrating business. A vaccine that triggers immune responses that effectively control early infection by the simian counterpart of HIV in macaques seems promising

Author

Johnson, R. Paul

Subjects
Macaques -- Diseases -- Forecasts and trends, AIDS (Disease) -- Research, AIDS research -- Forecasts and trends, AIDS vaccines -- Product development, Market trend/market analysis, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

HIV is a highly mutable virus that has evolved over millennia to escape host control (1). It is not surprising, therefore, that researchers have faced numerous challenges in inducing effective [...]

Published
2011

5. Vaccinology: Persistence pays off.

Author

Johnson, R. Paul

Subjects
*T cells, *AIDS treatment, *SIMIAN immunodeficiency virus, *VACCINATION, *PRIMATE diseases, *VACCINES, *PATHOGENIC microorganisms, *THERAPEUTICS
Abstract

The article focuses on a research made by Scott G. Hansen and colleagues on the creation of vaccines for the treatment of AIDS and simian immunodeficiency virus (SIV) found in macaques. According to their research, in rhesus macaques, the stimulation of a type of T cell may limit the initial stages of replication of SIV. Moreover, their work shows that the immune system can determine pathogens years after the first exposure with the use a specialized population of T cells called memory T cells.

Published
2011
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