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2. One-Pot Synthesis of Protein-Embedded Metal–OrganicFrameworks with Enhanced Biological Activities.

Author

Lyu, Fengjiao, Zhang, Yifei, Zare, Richard N., Ge, Jun, and Liu, Zheng

Subjects
*CHEMICAL synthesis, *PROTEINS, *COPRECIPITATION (Chemistry), *PEROXIDASE, *SOLUTION (Chemistry), *ORGANIC compounds
Abstract

Protein molecules were directly embeddedin metal–organicframeworks (MOFs) by a coprecipitation method. The protein moleculesmajorly embedded on the surface region of MOFs display high biologicalactivities. As a demonstration of the power of such materials, theresulting Cyt cembedded in ZIF-8 showed a 10-foldincrease in peroxidase activity compared to free Cyt cin solution and thus gave convenient, fast, and highly sensitivedetection of trace amounts of explosive organic peroxides in solution. [ABSTRACT FROM AUTHOR]

Published
2014
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