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One-Pot Synthesis of Protein-Embedded Metal–OrganicFrameworks with Enhanced Biological Activities.

Authors :
Lyu, Fengjiao
Zhang, Yifei
Zare, Richard N.
Ge, Jun
Liu, Zheng
Source :
Nano Letters. Oct2014, Vol. 14 Issue 10, p5761-5765. 5p.
Publication Year :
2014

Abstract

Protein molecules were directly embeddedin metal–organicframeworks (MOFs) by a coprecipitation method. The protein moleculesmajorly embedded on the surface region of MOFs display high biologicalactivities. As a demonstration of the power of such materials, theresulting Cyt cembedded in ZIF-8 showed a 10-foldincrease in peroxidase activity compared to free Cyt cin solution and thus gave convenient, fast, and highly sensitivedetection of trace amounts of explosive organic peroxides in solution. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
15306984
Volume :
14
Issue :
10
Database :
Academic Search Index
Journal :
Nano Letters
Publication Type :
Academic Journal
Accession number :
98806348
Full Text :
https://doi.org/10.1021/nl5026419