1. Depressed Systolic Function after a Prolonged and Strenuous Exercise
- Author
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A. Ménétrier, Damien Vitiello, Iris Schuster, Sté Phane Nottin, Philippe Obert, Thomas Rupp, Nicolas Tordi, Cyril Reboul, Johan Cassirame, Physiopathologie des adaptations cardiovasculaires à l'Exercice, Université d'Avignon et des Pays de Vaucluse ( UAPV ), Laboratoire Culture, sport, santé, société - UFC ( C3S ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Université de Franche-Comté ( UFC ), Marqueurs pronostiques et facteurs de régulations des pathologies cardiaques et vasculaires - UFC ( PCVP / CARDIO ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ), Laboratoire Interuniversitaire de Biologie de la Motricité ( LIBM ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] ( UJM ) -Université Savoie Mont Blanc ( USMB [Université de Savoie] [Université de Chambéry] ), Caractéristiques féminines des dysfonctions des interfaces cardio-vasculaires ( EA 2992 ), Université Montpellier 1 ( UM1 ) -Université de Montpellier ( UM ), EA4278 Laboratoire de Pharm-Ecologie Cardiovasculaire ( LaPEC ), Avignon Université (AU), Laboratoire Culture, sport, santé, société - UFC (EA 4660) (C3S), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Marqueurs pronostiques et facteurs de régulations des pathologies cardiaques et vasculaires - UFC ( EA 3920) (PCVP / CARDIO), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Laboratoire Interuniversitaire de Biologie de la Motricité (LIBM ), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry]), Caractéristiques féminines des dysfonctions des interfaces cardio-vasculaires (EA 2992), Université Montpellier 1 (UM1)-Université de Montpellier (UM), EA4278 Laboratoire de Pharm-Ecologie Cardiovasculaire (LaPEC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)
- Subjects
Adult ,Male ,Tachycardia ,medicine.medical_specialty ,Rotational rate ,Rest ,[SDV]Life Sciences [q-bio] ,Strenuous exercise ,Physical Exertion ,Physical Therapy, Sports Therapy and Rehabilitation ,Speckle tracking echocardiography ,Systolic function ,030204 cardiovascular system & hematology ,Ventricular Dysfunction, Left ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Heart Rate ,[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathology ,Internal medicine ,Systolic strain ,medicine ,Humans ,Orthopedics and Sports Medicine ,Diastolic function ,ComputingMilieux_MISCELLANEOUS ,business.industry ,Incremental test ,Bicycling ,Echocardiography ,Cardiology ,medicine.symptom ,business ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology ,030217 neurology & neurosurgery - Abstract
AB Introduction: Prolonged and strenuous exercise (PSE) induces transient left ventricular (LV) dysfunction. Although a consensus exists regarding the decrease in diastolic function, the existence of a decrease in systolic function by a PSE remains controversial, probably due to the transient tachycardia and changes in loading conditions observed upon the completion of exercise. Therefore, the objective was to evaluate LV systolic function before and after a PSE using two-dimensional speckle tracking echocardiography not only at rest but also during incremental tests to adjust heart rates (HR). Methods and Results: Sixteen healthy young men (23 +/- 3 yr old) performed a 3-h period of intensity-controlled upright cycling. LV strain (S), systolic strain rate (SR), rotation, and systolic rotational rate were evaluated by two-dimensional speckle tracking echocardiography before and after a 3-h period of PSE at rest and during incremental tests. Posttest evaluation was performed once the HR had returned to the pretest value. Under resting conditions, parameters of systolic function were either unchanged or increased after the PSE. However, during the incremental test, all LV systolic SR and apical rotational rates were decreased after PSE (radial SR at workload 3 (W3): 2.21 +/- 0.12.s-1 vs 1.87 +/- 0.10.s-1, P < 0.01 and apical rotational rate at W3: 128 +/- 28 deg.s-1 vs 105 +/- 26 deg.s-1, P < 0.05). Regression analyses between LV systolic SR and HR showed lower y-intercepts without differences in slopes, suggesting a decrease of both global and regional systolic functions irrespective of HR after the PSE. Conclusion: Our findings based on LV S and SR data during incremental tests demonstrate that the 3-h period of PSE induces LV systolic dysfunction
- Published
- 2013