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Start Over Author "Vanessa Plantier" Journal medecine sciences : m/s
1 results on '"Vanessa Plantier"'

1. [Calpain as a new therapeutic target for treating spasticity after a spinal cord injury]

Author

Vanessa, Plantier and Frédéric, Brocard

Subjects
Motor Neurons, Spinal Cord, Calpain, Muscle Spasticity, Proteolysis, Animals, Humans, Molecular Targeted Therapy, Voltage-Gated Sodium Channels, Spinal Cord Injuries
Abstract

After a spinal cord injury (SCI), patients develop spasticity, a motor disorder characterized by hyperreflexia and stiffness of muscles. Spasticity results from alterations in motoneurons with an upregulation of their persistent sodium current (I

Published
2017

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