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[Calpain as a new therapeutic target for treating spasticity after a spinal cord injury]

Authors :
Vanessa, Plantier
Frédéric, Brocard
Source :
Medecine sciences : M/S. 33(6-7)
Publication Year :
2017

Abstract

After a spinal cord injury (SCI), patients develop spasticity, a motor disorder characterized by hyperreflexia and stiffness of muscles. Spasticity results from alterations in motoneurons with an upregulation of their persistent sodium current (I

Details

Language :
French
ISSN :
19585381
Volume :
33
Issue :
6-7
Database :
OpenAIRE
Journal :
Medecine sciences : M/S
Accession number :
edsair.pmid..........ff0167c3ca527fb414469f07610e2e48