1. The COVID-19 pandemic: is there a role for magnesium? Hypotheses and perspectives
- Author
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Stefano Iotti, Federica I Wolf, Jeanette A.M. Maier, André Mazur, University of Bologna, Università cattolica del Sacro Cuore [Roma] (Unicatt), Unité de Nutrition Humaine (UNH), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Università degli Studi di Milano [Milano] (UNIMI), Iotti S., Wolf F., Mazur A., Maier J.A., University of Bologna/Università di Bologna, Università cattolica del Sacro Cuore = Catholic University of the Sacred Heart [Roma] (Unicatt), and Università degli Studi di Milano = University of Milan (UNIMI)
- Subjects
0301 basic medicine ,Time Factors ,T-Lymphocytes ,Clinical Biochemistry ,Disease ,magnesium ,030204 cardiovascular system & hematology ,Biochemistry ,Pathogenesis ,0302 clinical medicine ,Epidemiology ,Pandemic ,Medicine ,Endothelial dysfunction ,Inflammation Mediator ,[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism ,Prognosis ,3. Good health ,Host-Pathogen Interaction ,Host-Pathogen Interactions ,Disease Progression ,Inflammation Mediators ,medicine.symptom ,Coronavirus Infections ,Human ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Prognosi ,Pneumonia, Viral ,Inflammation ,Proinflammatory cytokine ,Betacoronavirus ,03 medical and health sciences ,Animals ,Humans ,[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology ,Pandemics ,Molecular Biology ,Betacoronaviru ,Animal ,Coronavirus Infection ,SARS-CoV-2 ,business.industry ,pandemic ,COVID-19 ,medicine.disease ,030104 developmental biology ,T-Lymphocyte ,inflammation ,Immunology ,business ,Magnesium Deficiency - Abstract
International audience; More and more studies are accumulating about COVID-19. Some aspects of the pathogenesis of the disease recall events occurring in Mg deficiency, such as a drop of T cells, increased plasma concentration of inflammatory cytokines, and endothelial dysfunction. We hypothesize that a low Mg status, which is rather common, might foment the transition from mild to critical clinical manifestations of the disease. Epidemiological, clinical, and fundamental research is needed to clarify the potential role of Mg deficiency in COVID-19.
- Published
- 2020