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A letter to the editor is presented in response to the article on musculoskeletal radiology service at Great Ormond Street Hospital (GOSH) in London, England.

The article focuses on a study which shows that a stem-cell-based, tissue-engineered tracheal transplant is a potential therapeutic option for patients. It mentions that patients treated with autologous stemcell-derived transplants do not need immunosuppression. It reflects that normal airway and lung function, high quality of life, and the elimination of the need for repeated surgical interventions were the end-points of a tracheal replacement in children.

The article discusses renovascular disease as a cause of hypertension in children. The pathogenesis, diagnostic methods, and various medical treatments associated with the condition are explained. The various syndromes that have been linked with renovascular hypertension, including medial fibroplasia and neurofibromatosis, are examined. The role of vasculitides such as Takayasu's disease in studies of children with renovascular hypertension in India and South Africa are analyzed. The genetic component of the disease and the difficulties of diagnosing the condition in children are discussed.