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Start Over Author "Sara Capellini" Journal journal of the american college of cardiology
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1. THE POSSIBLE ROLE OF GENETIC VARIANTS IN PREDICTING ANTRACICLYNE-INDUCED CARDIOTOXICITY

Author

Sara Capellini, Ilaria Papa, Savina Nodari, Edda Simoncini, Luca Ambrosiani, Marco Triggiani, Annalisa Pizzuto, Martina Fragni, Sandra Sigala, Vito Amoroso, and Graziella Bonetti

Subjects
Cardiotoxicity, Anthracycline, business.industry, Genetic variants, food and beverages, biochemical phenomena, metabolism, and nutrition, medicine.disease, Breast cancer, medicine, Cancer research, Non metastatic, In patient, Cardiology and Cardiovascular Medicine, business, Drug metabolism
Abstract

interpatient variability in anthracycline(ANT)metabolism may contribute to the development of cardiotoxicity(CTX). Aim of the study:to verify the role of genetic variants of enzymes involved in drug metabolism to predict ANT-induced CTX risk in patients(pts)with non metastatic breast Cancer(BC).

Published
2014

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