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Your search keyword '"Meng-Hua Wang"' showing total 3 results
Start Over Author "Meng-Hua Wang" Journal journal of natural products
3 results on '"Meng-Hua Wang"'

1. Chetocochliodins A-I, Epipoly(thiodioxopiperazines) from Chaetomium cochliodes

Author

Meng-Hua Wang, Bingda Sun, Gang Ding, Xian-Mei Tan, Meng Yu, Zhong-Mei Zou, Xiaoyan Zhang, and Shu-Bin Niu

Subjects
Pharmacology, biology, 010405 organic chemistry, Organic Chemistry, Pharmaceutical Science, Fungus, Chaetomium, biology.organism_classification, 01 natural sciences, 0104 chemical sciences, Analytical Chemistry, Microbiology, 010404 medicinal & biomolecular chemistry, Complementary and alternative medicine, Drug Discovery, Molecular Medicine, Chaetomium cochliodes
Abstract

Nine new epipoly(thiodioxopiperazine) (ETP) analogues, chetocochliodins A-I (1–9), along with two known ones, chetoseminudins E and C (10 and 11), were purified from the fungus Chaetomium cochliode...

Published
2020

2. Chetocochliodins A-I, Epipoly(thiodioxopiperazines) from

Author

Meng-Hua, Wang, Xiao-Yan, Zhang, Xian-Mei, Tan, Shu-Bin, Niu, Bing-Da, Sun, Meng, Yu, Gang, Ding, and Zhong-Mei, Zou

Subjects
Magnetic Resonance Spectroscopy, Molecular Structure, X-Ray Diffraction, Circular Dichroism, Fermentation, Chaetomium, Sulfides, Piperazines, Indole Alkaloids
Abstract

Nine new epipoly(thiodioxopiperazine) (ETP) analogues, chetocochliodins A

Published
2020

3. Trichoderpyrone, a Unique Polyketide Hybrid with a Cyclopentenone–Pyrone Skeleton from the Plant Endophytic Fungus Trichoderma gamsii

Author

Tao Zhang, Hai Shang, Zhong-Mei Zou, Gang Ding, Xingzhong Liu, Hong-Wu Zhang, Li Li, Shu-Bin Niu, Gui-shan Zhang, Luying Li, Meng-Hua Wang, Lin Chen, Hong-Mei Jia, and Meng Yu

Subjects
Cyclopentenone, Stereochemistry, Pharmaceutical Science, 010402 general chemistry, 01 natural sciences, Analytical Chemistry, HeLa, Polyketide, chemistry.chemical_compound, Drug Discovery, Botany, Humans, Nuclear Magnetic Resonance, Biomolecular, Trichoderma, Pharmacology, Molecular Structure, biology, 010405 organic chemistry, Organic Chemistry, Hep G2 Cells, Plants, Endophytic fungus, biology.organism_classification, Skeleton (computer programming), Pyrone, 0104 chemical sciences, Complementary and alternative medicine, chemistry, Polyketides, Molecular Medicine, Drug Screening Assays, Antitumor, Two-dimensional nuclear magnetic resonance spectroscopy, HeLa Cells
Abstract

Trichoderpyrone (1), a unique polyketide with a cyclopentenone-pyrone hybrid skeleton, was isolated from the plant endophytic fungus Trichoderma gamsii. The structure of 1 was determined by detailed analysis of NMR data together with comparison of chemical shift values of similar fragments. The relative and absolute configurations were established by NOESY correlations and CD experiment. Trichoderpyrone (1) displayed weak cytotoxic activities against A549, HepG2, and HeLa cancer cell lines. 1 might originate from a hybrid biosynthetic pathway through two nonreduced (NR) polyketide megasynthetases.

Published
2017

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