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The article focuses on calling for papers on "Health and the 2024 Elections Globally," highlighting the significant influence of governments on health policies and inviting submissions to the periodical that address healthcare issues in national, regional or global contexts during election years.

The article focuses on the bacterial aspects of dirty money and the historical concern regarding the transmission of infectious material through currency. While previous worries highlighted the potential danger of dirty paper money, bacteriological investigations failed to find significant microbial distribution on paper currency, suggesting that the composition of printed bills might inhibit bacterial growth.

An editorial is presented the importance of health as a central policy issue in the 2024 US election and the need for rigorous research to inform health care and public health policies. Topics include various health-related challenges, such as health disparities, immigration policies, LGBTQ rights, firearm regulations, and the impact of the economy on mental health and access to essential needs.

The article focuses on concerns raised in response to a recent Viewpoint discussing the threats and opportunities associated with the rapid growth of mega-journals. It authors express concerns about issues not discussed in the original Viewpoint, such as the integrity of medical literature due to special issue manipulation, retraction rates, and paper-mill articles in mega-journals.

An introduction is presented in which the editor discusses the guidelines for manuscripts on cardiovascular disease to- be considered for publication.

The poem "Aftermath" by Stacy R. Nigliazzo is presented. First line: Asters reach from paper cups across the nurses' desk. ; Last Line: Some of us cry. All of us get back to work.

This study assessed the presence, amount, and sensitivity of personally identifiable information and personal health information found in hospital recycling bins in Toronto, Ontario, Canada. [ABSTRACT FROM AUTHOR]

The article focuses on concerns related to the rapid growth of mega-journals. It authors raise issues such as special issue manipulation, retraction rates, and paper-mill articles in mega-journals that threaten the integrity of the medical literature. It also discuss the need for differentiation between mega-journals with rigorous peer review processes and those susceptible to manipulation, and they highlight the concern of potentially predatory behavior in some mega-journals.

The article focuses on a study on the risk of heart failure associated with the TTR Val122Ile mutation, which references a research paper published within the issue. Topics discussed include the treatment of amyloid-related heart failure, characterization of hATTR-CM autosomal-dominant cardiac disease, and the implications of the study.

The article recalls a paper, published in the November 10, 1923 issue, which discussed why moonshine whiskey is considered a menace to health. Topics discussed include the alcohol content of whiskey, a comparison of the prevalence of alcoholism in the past and the present time, and the debate on whether the harmful effects of new whiskey is due to its higher alcohol content or its fusel oil.

The author discusses a research paper on the link between maternal antidepressant prescriptions filled during pregnancy and standardized language and mathematics test scores of school-aged children, which references a study by J. Christensen et al., published within the issue. Topics discussed include the prevalence of depression in pregnant women, the difference found for standardized mathematics scores among children, and the implications of the study for antidepressant use in pregnancy.

The article focuses on a study on the efficacy of vasopressin and methylprednisolone in combination with standard advanced life support during resuscitation among in-hospital cardiac arrest patients, which references a research paper by L. W. Andersen et al., published within the issue. Topics discussed include the prevalence of cardiopulmonary arrest in hospital patients in the U.S., and an improvement in return of spontaneous circulation among patients.

The article focuses on concerns related to the rapid growth of mega-journals. It authors raise issues such as special issue manipulation, retraction rates, and paper-mill articles in mega-journals that threaten the integrity of the medical literature. It also discuss the need for differentiation between mega-journals with rigorous peer review processes and those susceptible to manipulation, and they highlight the concern of potentially predatory behavior in some mega-journals.

Importance: Recent discussion has focused on questions related to the repeal and replacement of portions of the Affordable Care Act (ACA). However, issues central to the future of health and health care in the United States transcend the ACA provisions receiving the greatest attention. Initiatives directed to certain strategic and infrastructure priorities are vital to achieve better health at lower cost.Objectives: To review the most salient health challenges and opportunities facing the United States, to identify practical and achievable priorities essential to health progress, and to present policy initiatives critical to the nation's health and fiscal integrity.Evidence Review: Qualitative synthesis of 19 National Academy of Medicine-commissioned white papers, with supplemental review and analysis of publicly available data and published research findings.Findings: The US health system faces major challenges. Health care costs remain high at $3.2 trillion spent annually, of which an estimated 30% is related to waste, inefficiencies, and excessive prices; health disparities are persistent and worsening; and the health and financial burdens of chronic illness and disability are straining families and communities. Concurrently, promising opportunities and knowledge to achieve change exist. Across the 19 discussion papers examined, 8 crosscutting policy directions were identified as vital to the nation's health and fiscal future, including 4 action priorities and 4 essential infrastructure needs. The action priorities-pay for value, empower people, activate communities, and connect care-recurred across the articles as direct and strategic opportunities to advance a more efficient, equitable, and patient- and community-focused health system. The essential infrastructure needs-measure what matters most, modernize skills, accelerate real-world evidence, and advance science-were the most commonly cited foundational elements to ensure progress.Conclusions and Relevance: The action priorities and essential infrastructure needs represent major opportunities to improve health outcomes and increase efficiency and value in the health system. As the new US administration and Congress chart the future of health and health care for the United States, and as health leaders across the country contemplate future directions for their programs and initiatives, their leadership and strategic investment in these priorities will be essential for achieving significant progress. [ABSTRACT FROM AUTHOR]

2 Levine, M.: The Value of Boric Acid Canning Compound in Food Preservation, J. Home Econom. When treated clothes are brushed, the arsenic compound may pollute the air more than was the case with the now forbidden arsenic-bearing wall paper. JAMA Revisited JAMA. [Extracted from the article]

An introduction to papers in the current issue of "JAMA: The Journal of the American Medical Association," is presented with topics including costs associated with drug research and development, assessment of the median profitability of pharmaceutical companies and trends in drug pricing.

The authors respond to a letter to the editor about their study on the incidence of pancreatic cancer by age and sex in the U.S. from 2000 to 2018. Topics discussed include the underlying histopathological subtypes as a risk factor for pancreatic cancer in young women, the difference in the study's methodology and conclusions compared to other similar research papers, and their disagreement to a recommendation to help decrease the incidence of pancreatic cancer.

The article explores a study on the effects of a home-based walking exercise behavior change intervention delivered by physical therapists in patients with peripheral artery disease (PAD), which references a research paper by L. M. Bearne et al., published within the issue. Topics discussed include the sessions included in the intervention, the homogeneity of the supervised treadmill exercise intervention, and the benefit of a home-based exercise intervention to people with PAD.

Hepatitis A vaccination also has largely replaced immunoglobulin as a preexposure or postexposure prophylaxis due to greater and longer-lasting efficacy and safety, the organization said. Global Health The World Health Organization (WHO) backed a single-dose strategy for hepatitis A vaccines for children aged 12 years or older and for hepatitis A outbreaks in a new position paper. [Extracted from the article]

The author discusses a research paper on the results of the ACTIV-4B Outpatient Thrombosis Prevention Trial, which references a study by J. M. Connors et al., published within the issue. Topics discussed include the association of COVID-19 disease with an inflammatory and hyper-coagulable condition, randomized clinical trials of antithrombotic therapies on COVID-19 patients, strengths of the trial, and the implications of the trial.

The author discusses a double-blind randomized clinical trial on the combination of varenicline and a single nicotine replacement therapy to enhance smoking cessation rate, which references a research paper published within the issue. Topics discussed include the primary outcome of self-reported seven-day point prevalence abstinence, the strengths of the study, and two clinical guidelines on initial smoking cessation therapy.

The article discusses a study on the adverse outcomes of tramadol or codeine among residents of Catalonia, Spain, which references a research paper published within the issue. Topics discussed include the use of propensity score matching in the study, the incidence of all-cause mortality and cardiovascular events following tramadol and codeine prescriptions, and the difference in the patterns of codeine prescribing in the U.S. from Europe.

The article focuses on a research paper on the safety of a COVID-19 vaccine during the first six months, referencing a study published in an issue of "The Lancet Infectious Diseases," which reveals that the symptoms were mild and short-lived.

Importance: Hepatitis C virus (HCV) infects more than 185 million individuals worldwide. Twenty percent of patients chronically infected with HCV progress to cirrhosis. New, simpler therapeutics using direct-acting antivirals that target various stages of the HCV life cycle are in development to eradicate HCV without concomitant interferon.Objectives: To summarize published evidence on safety, efficacy (measured by a sustained virologic response [SVR], which is the treatment goal of undetectable plasma HCV RNA 12 or 24 weeks after therapy completion), and tolerability of current US Food and Drug Administration-approved interferon-based regimens and oral interferon-free regimens used for treating HCV infection and coinfection with human immunodeficiency virus (HIV) and HCV; to provide treatment recommendations for specialists and generalists based on published evidence.Evidence Review: A literature search of Web of Science, Scopus, Embase, Agricola, Cochrane Library, Cinahl Plus, ClinicalTrials.gov, Conference Papers Index, Gideon, PsycINFO, Google Scholar, and Oaister was conducted from January 1, 2009, to May 30, 2014. Publications describing phase 2, 3, and 4 studies evaluating the treatment of HCV were included. Forty-one studies involving 19,063 adult patients were included. Strength of clinical data and subsequent HCV treatment recommendations were graded according to the Oxford Centre for Evidence-Based Medicine.Findings: Patients infected with HCV genotype 1 represent 60% to 75% of HCV infections in the United States. Hepatitis C virus genotype 1 is more difficult to cure than genotype 2 or genotype 3. Patients with HCV genotype 1 should receive treatment with sofosbuvir + pegylated interferon + ribavirin because of the shorter duration of therapy and high rates of SVR (89%-90%). Simeprevir + pegylated interferon + ribavirin is an alternative for patients with HCV genotype 1 (SVR, 79%-86%). Patients with HCV genotypes 2 and 3, representing 20% to 29% of US HCV infections, should receive therapy with sofosbuvir + ribavirin alone (SVR for genotype 2, 12 weeks' duration: 82%-93%; SVR for genotype 3, 24 weeks' duration, 80%-95%). Patients with HIV-HCV coinfection and patients with compensated cirrhosis (ie, cirrhosis but preserved synthetic liver function) should receive the same treatment as HCV-monoinfected patients.Conclusions and Relevance: New, short-duration, simpler therapies result in high SVR rates for HCV-infected patients. In conjunction with increased screening for HCV as suggested by recent Centers for Disease Control and Prevention guidelines, availability of new therapies may lead to the treatment of many more people with chronic HCV infection. [ABSTRACT FROM AUTHOR]

IMPORTANCE Hepatitis C virus (HCV) infects more than 185 million individuals worldwide. Twenty percent of patients chronically infected with HCV progress to cirrhosis. New, simpler therapeutics using direct-acting antivirals that target various stages of the HCV life cycle are in development to eradicate HCV without concomitant interferon. OBJECTIVES To summarize published evidence on safety, efficacy (measured by a sustained virologic response [SVR], which is the treatment goal of undetectable plasma HCV RNA 12 or 24 weeks after therapy completion), and tolerability of current US Food and Drug Administration-approved interferon-based regimens and oral interferon-free regimens used for treating HCV infection and coinfection with human immunodeficiency virus (HIV) and HCV; to provide treatment recommendations for specialists and generalists based on published evidence. EVIDENCE REVIEW A literature search of Web of Science, Scopus, Embase, Agricola, Cochrane Library, Cinahl Plus, ClinicalTrials.gov, Conference Papers Index, Gideon, PsycINFO, Google Scholar, and Oaister was conducted from January 1, 2009, to May 30, 2014. Publications describing phase 2, 3, and 4 studies evaluating the treatment of HCV were included. Forty-one studies involving 19 063 adult patients were included. Strength of clinical data and subsequent HCV treatment recommendations were graded according to the Oxford Centre for Evidence-Based Medicine. FINDINGS Patients infected with HCV genotype 1 represent 60%to 75%of HCV infections in the United States. Hepatitis C virus genotype 1 is more difficult to cure than genotype 2 or genotype 3. Patients with HCV genotype 1 should receive treatment with sofosbuvir + pegylated interferon + ribavirin because of the shorter duration of therapy and high rates of SVR (89%-90%). Simeprevir + pegylated interferon + ribavirin is an alternative for patients with HCV genotype 1 (SVR, 79%-86%). Patients with HCV genotypes 2 and 3, representing 20%to 29% of US HCV infections, should receive therapy with sofosbuvir + ribavirin alone (SVR for genotype 2, 12 weeks' duration: 82%-93%; SVR for genotype 3, 24 weeks' duration, 80%-95%). Patients with HIV-HCV coinfection and patients with compensated cirrhosis (ie, cirrhosis but preserved synthetic liver function) should receive the same treatment as HCV-monoinfected patients. CONCLUSIONS AND RELEVANCE New, short-duration, simpler therapies result in high SVR rates for HCV-infected patients. In conjunction with increased screening for HCV as suggested by recent Centers for Disease Control and Prevention guidelines, availability of new therapiesmay lead to the treatment of many more people with chronic HCV infection. [ABSTRACT FROM AUTHOR]

The article reports on the release of an Interagency Working Group on Asbestos in Consumer Products White Paper by the U.S. Food and Drug Administration (FDA) on the detection and identification of asbestos fibers in talc-containing cosmetic products.

The article reports on the discussion paper issued by the U.S. Food and Drug Administration (FDA) as of February 2022 to discuss its regulation of 3-dimensional (3D) printing of medical devices at the point of care like health care facilities.

The article discusses papers published within the issue, including one on the U.S. Preventive Services Task Force's (USPSTF) Recommendation Statement on screening in primary care settings for latent tuberculosis infection in adults and another on the Evidence Report and systemic review that supports the USPSTF recommendations.

The article reports on a study which reveals the effectiveness of a high-intensity interval training aerobic exercise program in improving cardiorespiratory fitness and suppressing prostate cancer progression, which references a research paper published in an issue of the "JAMA Oncology".

The article reports on a study on the association of an increase in risk of birth complications or neurodevelopmental problems in children to antipsychotic use by their mothers during pregnancy, which references a research paper published in an issue of the "JAMA Internal Medicine".

The article reports on a study which reveals that limiting screen time, such as watching television, using mobile phone and playing video games, during the acute period after concussion could speed up recovery, based on a research paper published in an issue of the "JAMA Pediatrics".

The article reports on a study on the link between sleep duration and cognitive conditions and other adverse health outcomes for older adults, such as depression, which references a research paper published in an issue of the "JAMA Neurology".

The article focuses on a study on the prevalence of aspergillosis in patients with COVID-19 virus who are hospitalized in an intensive care unit, which references a research paper published in an issue of the "Emerging Infectious Diseases".

The article reports on a study on the efficacy of bacterial immunotherapy in reducing wheezing attacks in children caused by a rhinovirus or respiratory syncytial virus, which references a research paper published in an issue of the "American Journal of Respiratory and Critical Care Medicine".

The article focuses on a study on the probability of completing advanced care planning activities by middle-aged and older adults after receiving personalized reports and brochures, which references a research paper published in an issue of the "Annals of Internal Medicine".

The article focuses on a study on the association of sodium chloride and potassium chloride consumption to lower rate of stroke, cardiovascular events and death, which references a research paper published in an issue of the "New England Journal of Medicine".

The article reports on a study on the efficacy of polypill in treating patients with hypertension, which references a research paper published in an issue of the "Lancet," and discusses the contents of the polypill, such as irbesartan, amlodipine and indapamide.

The article reports that the North American Menopause Society (NAMS) recently published a position paper on the effectiveness of various nonhormonal options for managing menopausal vasomotor symptoms. According to the findings, some approaches commonly assumed to be helpful, such as avoiding hot beverages, exercising, or taking herbal supplements, don't have clinical evidence to support their effectiveness.

A commentary on a paper which compared the profitability of pharmaceutical companies with that of other large companies and a report which assessed the expenditures associated with drug research and development, is presented. Topics covered include median net income margin in the pharmaceutical industry, need to consider the economics of pharmaceuticals and estimates of the cost of new drug discovery.

The article features "Face Mask," a synthetic polymer on paint, and pencil on paper artwork created by American artist Bruce Nauman in 1981. Information on Nauman's personal and educational background, the art materials he used and the artistic style he adopted for the painting is presented. An interpretation of the painting as a self-referential and allusion to the human body is offered.

In this narrative medicine essay, the author, who transitioned from paper and pen to computer-generated electronic health record keeping, wonders whether self-select menu items on the EHR ultimately dehumanize both the patient and the physician. [ABSTRACT FROM AUTHOR]

The article presents a reprint of the article "Diagnostic Problems: Guest Editorial" which appears in a 1957 issue of the journal, and it mentions clinical pathological conferences and medical education and training in the twentieth century. Chemotherapy and antibiotics are examined, along with clinical symptomatology. Morphologic pathology and pathological physiology are assessed, as well as pathologists and the age of paper chromatography.

The article profiles American artist Larry Bell. Topics discussed include the career history of Bell, his decision to have his own glass coating device which allows for the vaporization of metallic substances that get deposited on the glass as they cool, allowing him to create large-sized sculptures, and his use of the same technique in paper starting in the late 1970s, which became known as vapor drawings. Also mentioned is an example of his vapor drawings titled "Frog Pond."

The poem "On a Surgeon Poet" by Eric James Forsbergh is presented. First line: A wound on paper isn't quite a wound. Last line: an endless field of snow. And I miss the imperative of blood.

The authors reflect on quality metrics for red blood cells (RBC) storage duration and transfusion. They discuss a paper by Dhabangi and colleagues within the issue which presents the results of a randomized noninferiority trial that used reduction of blood lactate concentration as a surrogatye to deliver oxygen to tissues and is first to indicate that RBCs transfusion of longer storage duration is not inferior to RBC transfusion of shorter duration in reversing oxygen shock or debt.

This section presents abstracts of research papers on medical topics, including "Promoting Safe Use of Isotretinoin by Increasing Contraceptive Knowledge," "Patient Demands and Requests for Cancer Tests and Treatments" and "Efficacy and Optimization of Palivizumab Injection Regimens Against Respiratory Syncytial Virus Infection".

This article discusses a research paper on the effect of initial oral glucose-lowering medication for diabetes mellitus on the need for treatment intensification. It references the study "Initial Choice of Oral Glucose-Lowering Medication for Diabetes Mellitus: A Patient-Centered Comparative Effectiveness Study," by Seth A. Berkowitz et al., published in an issue of the "JAMA Internal Medicine". It tackles the importance of the study and the use of metformin as treatment for type 2 diabetes.

The article discusses papers published within the issue, including studies by P. F. Whiting et al. and K. P. Hill et al. on the pharmacology, indications, benefits, adverse effects and laws related to medical marijuana and the cannabinoids.

The article discusses a research paper on the association between implantable cardioverter-defibrillator (ICD) implantation rates and mortality in Medicare patients treated at U.S. hospitals between 2007 and 2010. It references the study "Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Acute Myocardial Infarction," by S. D. Pokorney et al., published within the issue. It tackles the guidelines for ICD implantation and the study's limitations.

The article presents abstracts for several medical papers covering topics such as neurology, plastic surgery, and pediatrics.