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Your search keyword '"Ahmad, Waseem"' showing total 3 results
Start Over Author "Ahmad, Waseem" Journal international journal of molecular sciences
3 results on '"Ahmad, Waseem"'

1. Deleterious Variants in WNT10A, EDAR, and EDA Causing Isolated and Syndromic Tooth Agenesis: A Structural Perspective from Molecular Dynamics Simulations

Author

Parveen, Asia, primary, Khan, Sher Alam, additional, Mirza, Muhammad Usman, additional, Bashir, Hina, additional, Arshad, Fatima, additional, Iqbal, Maria, additional, Ahmad, Waseem, additional, Wahab, Ahsan, additional, Fiaz, Amal, additional, Naz, Sidra, additional, Ashraf, Fareeha, additional, Mobeen, Tayyaba, additional, Aziz, Salman, additional, Ahmed, Syed Shoaib, additional, Muhammad, Noor, additional, Hassib, Nehal F., additional, Mostafa, Mostafa I., additional, Gaboon, Nagwa E., additional, Gul, Roquyya, additional, Khan, Saadullah, additional, Froeyen, Matheus, additional, Shoaib, Muhammad, additional, and Wasif, Naveed, additional

Published
2019
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2. Keratin K15 as a Biomarker of Epidermal Stem Cells

Author

Ian C. Mackenzie, Amrita Bose, Ahmad Waseem, and Muy-Teck Teh

Subjects
intermediate filaments, Cellular differentiation, Review, Biology, Stem cell marker, Catalysis, lcsh:Chemistry, Inorganic Chemistry, Keratin, Animals, Humans, Physical and Theoretical Chemistry, lcsh:QH301-705.5, Molecular Biology, Spectroscopy, chemistry.chemical_classification, pluripotent cells, integumentary system, Keratin-15, keratinocyte differentiation, Stem Cells, Organic Chemistry, transit-amplifying cells, basal keratinocytes, General Medicine, Computer Science Applications, Cell biology, Keratin 5, lcsh:Biology (General), lcsh:QD1-999, chemistry, Keratin 7, Keratin 8, Epidermis, Stem cell, Biomarkers, Adult stem cell
Abstract

Keratin 15 (K15) is type I keratin protein co-expressed with the K5/K14 pair present in the basal keratinocytes of all stratified epithelia. Although it is a minor component of the cytoskeleton with a variable expression pattern, nonetheless its expression has been reported as a stem cell marker in the bulge of hair follicles. Conversely, suprabasal expression of K15 has also been reported in both normal and diseased tissues, which is inconsistent with its role as a stem cell marker. Our recently published work has given evidence of the molecular pathways that seem to control the expression of K15 in undifferentiated and differentiated cells. In this article, we have critically reviewed the published work to establish the reliability of K15 as an epidermal stem cell marker.

Published
2013

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