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Researchers from Hainan University conducted a study on Alzheimer's disease, focusing on the role of annexin A2 (AnxA2) in the pathophysiology of the disease. Through genetic and cellular analysis, they found that AnxA2 plays a critical role in various biological processes related to Alzheimer's, such as neuroinflammation, apoptosis, and mitochondrial function maintenance. The study suggests that AnxA2 may have potential pathophysiological roles in Alzheimer's disease. For more information, the full article can be accessed for free at the Antioxidants journal website. [Extracted from the article]

A study conducted by researchers at Hainan University in China explores the potential relationship between impaired mitochondrial energy metabolism and p70 ribosomal protein S6 kinase (p70S6K) in Alzheimer's disease (AD). The researchers used bioinformatics methods to analyze transcriptomic data from patients with AD and Ab42-treated cells. They found that impaired mitochondrial energy metabolism is a potential pathological feature of AD and that p70S6K gene silencing reversed many of the changes induced by Ab42. This study provides new insights into the role of mitochondrial dysfunction in AD and highlights the potential therapeutic target of p70S6K. [Extracted from the article]