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Environmental exposures, such as ambient air pollution and household fuel use affect health and under-5 mortality (U5M) but there is a paucity of data in the Global South. This study examined early-life exposure to ambient particulate matter with a diameter of 2.5 µm or less (PM 2.5), alongside household characteristics (including self-reported household fuel use), and their relationship with U5M in the Navrongo Health and Demographic Surveillance Site (HDSS) in northern Ghana. We employed Satellite-based spatiotemporal models to estimate the annual average PM 2.5 concentrations with the Navrongo HDSS area (1998 to 2016). Early-life exposure levels were determined by pollution estimates at birth year. Socio-demographic and household data, including cooking fuel, were gathered during routine surveillance. Cox proportional hazards models were applied to assess the link between early-life PM2.5 exposure and U5M, accounting for child, maternal, and household factors. We retrospectively studied 48,352 children born between 2007 and 2017, with 1872 recorded deaths, primarily due to malaria, sepsis, and acute respiratory infection. Mean early-life PM 2.5 was 39.3 µg/m3, and no significant association with U5M was observed. However, Children from households using "unclean" cooking fuels (wood, charcoal, dung, and agricultural waste) faced a 73 % higher risk of death compared to those using clean fuels (adjusted HR = 1.73; 95 % CI: 1.29, 2.33). Being born female or to mothers aged 20–34 years were linked to increased survival probabilities. The use of "unclean" cooking fuel in the Navrongo HDSS was associated with under-5 mortality, highlighting the need to improve indoor air quality by introducing cleaner fuels. [ABSTRACT FROM AUTHOR]

[Display omitted] • Percentage reporting no SBS symptoms decreased from 83% in spring to 25% in winter. • The IAQ dissatisfaction rate exceeded 30% in winter. • Mo, Sb, Fe on the platform were 88, 52, and 27 times ambient in winter. • A lower relative humidity in winter increased metal particle emission. • PM control on the platform in winter should be urged. Metro systems play a crucial role in public transportation worldwide. Given that metro stations are unique built environments with a significant volume of daily commuters, ensuring a satisfactory air quality in these spaces becomes paramount. This study involved measurements of indoor air quality (IAQ), staff satisfaction, particulate matter (PM) chemical composition, and heavy metal health risks at a typical metro station in Tianjin over two seasons. Although the air exchange rate was sufficient to maintain a CO 2 concentration less than 1000 ppm, the proportion of staff reporting no sick-building symptoms decreased from 83 % in spring to 25 % in winter. An average mass concentration of PM with an aerodynamic diameter smaller than 2.5 μm (PM 2.5) of 68.0 ± 42.2 μg/m3 and an average PM 1 mass concentration of 51.8 ± 33.3 μg/m3 were observed on the platform in winter. PM 2.5 contained more metal in winter than in spring. PM 2.5 in winter contained more metal in winter than in spring. With a lower relative humidity in winter, the coefficient of friction between railway wheels and rails increased, thus increasing particle emission. The carcinogenic risk of Cr on the platform was unacceptable. Moreover, the health risks induced by Ba should be investigated. The findings indicate that PM control at metro stationss, particularly on platforms in winter, should be emphasized. [ABSTRACT FROM AUTHOR]

[Display omitted] Exposure scenario and receptor behavior significantly affect PM2.5 exposure quantity of persons and resident groups, which in turn influenced indoor or outdoor air quality & health management. An Internet of Things (IoT) system, EnvironMax+, was developed to accurately and conveniently assess residential dynamic PM2.5 exposure state. A university community "QC", as the application area, was divided into four exposure scenarios and five groups of residents. Low-cost mobile sensors and indoor/outdoor pollution migration (IOP) models jointly estimated multi-scenario real-time PM2.5 concentrations. Questionnaire was used to investigate residents' indoor activity characteristics. Mobile application (app) "Air health management (AHM)" could automatic collect residents' activity trajectory. At last, multi-scenario daily exposure concentrations of each residents-group were obtained. The results showed that residential exposure scenario was the most important one, where residents spend about 60 % of their daily time. Closing window was the most significant behavior affecting indoor contamination. The annual average PM2.5 concentration in the studied scenarios: residential scenario (RS) < public scenario (PS) < outdoor scenario (OS) < catering scenario (CS). Except for CS, the outdoor PM2.5 in other scenarios was higher than indoor by 5–10 μg/m3. The multi-scenario population weighted annual average exposure concentration was 37.1 μg/m3, which was 78 % of the annual average outdoor concentration. The exposure concentration of 5 groups: cooks > outdoor workers > indoor workers > students > the elderly, related to their daily activity time proportion in different exposure scenario. [ABSTRACT FROM AUTHOR]

Underground shopping malls (USMs) are often open or semi-open environments with interconnected passageways, resulting in the sharing of indoor air. However, indoor air quality (IAQ) within these spaces can vary due to many diverse emission sources. We investigated the relationships between IAQ and geographical areas, as well as IAQ and store types, within USMs, in Korea. In 2020, we studied 10 different USMs, with a total of 128 outlets. We conducted comprehensive IAQ assessments (including measurements of fine particles (PM 2.5), aldehydes, and volatile organic compounds (VOCs)) in stores, passages, and outdoor areas. The stores were categorized into three types: clothing, fashion accessories, and food services. Additionally, we measured environmental factors such as CO 2 levels and presence of storefront walls. PM 2.5 levels were higher outdoors, whereas aldehyde and VOC levels exhibited elevations within passages and the interior of stores than in the outdoor environment. The store-to-passage ratios for PM 2.5 , individual aldehydes, and VOC concentrations ranged from 1.06 to 4.93. Formaldehyde and total VOC (TVOC) concentrations were found to be elevated in clothing and fashion accessory stores, whereas PM 2.5 concentrations were more prominent in food service establishments. Specific individual compounds, including propionaldehyde, hexaldehyde, benzene, n -heptane, toluene, n -octane, xylene, d -limonene, n -undecane, n -dodecane, and ethylbenzene concentrations exhibited associations with store types. Multivariate regression models demonstrated positive associations between most aldehydes and VOCs with CO 2 concentrations and presence of storefront walls. This study underscored variations within USMs based on area and store type. Aldehyde and VOC concentrations were notably higher in clothing and fashion accessory stores than in food service outlets; these elevations were closely linked to CO 2 levels and presence of storefront walls. These findings suggest that monitoring CO 2 levels within USM stores, optimizing air-conditioning systems, and designing future stores without storefront walls can collectively contribute to an overall improvement of IAQ within USMs. [ABSTRACT FROM AUTHOR]

[Display omitted] • Emission characteristics are affected by material specifications and print setups. • Particle emissions are more sensitive to printing conditions than VOC emissions. • Personal exposures exceed US PM 2.5 standard for over 63% of the print runs. • 3D printing emits a complex mixture of up to 111 hazardous chemicals. • High emitting materials include nylon (particle), ASA (VOC), ABS and HIPS (both). Ultrafine particles and volatile organic compounds (VOCs) have been detected from material extrusion 3D printing, which is widely used in non-industrial environments. This study consolidates data of 447 particle emission and 58 VOC emission evaluations from a chamber study using a standardized testing method with various 3D printing scenarios. The interquartile ranges of the observed emission rates were 109–1011 #/h for particles and 0.2–1.0 mg/h for total VOC. Print material contributed largely to the variations of particle and total VOC emissions and determined the most abundantly emitted VOCs. Printing conditions and filament specifications, included printer brand, print temperature and speed, build plate heating setup, filament brand, color and composite, also affected emissions and resulted in large variations observed in emission profiles. Multiple regression showed that particle emissions were more impacted by various print conditions than VOC emissions. According to indoor exposure modeling, personal and residential exposure scenarios were more likely to result in high exposure levels, often exceeding recommended exposure limits. Hazardous VOCs commonly emitted from 3D printing included aromatics, aldehydes, alcohols, ketones, esters and siloxanes, among which were various carcinogens, irritants and developmental and reproductive toxins. Therefore, 3D printing emits a complex mixture of ultrafine particles and various hazardous chemicals, exposure to which may exceed recommended exposure limits and potentially induce acute, chronic, or developmental health effects for users depending on exposure scenarios. [ABSTRACT FROM AUTHOR]

[Display omitted] • ISIAQ STC34 has an open database of IEQ guidelines. • Thermal conditions (e.g., T and RH) and indoor pollutants (e.g., CO 2 , CH 2 O, PM, NO 2 , CO, and Rn) can be impacted by energy saving measures. • Health based guidelines exist for CH 2 O, PM 2.5 , PM 10 , NO 2 , CO, and Rn. • Guidelines can help in creating a balance between energy conservation, thermal comfort, and good IAQ. Buildings are constructed and operated to satisfy human needs and improve quality of life. Good indoor air quality (IAQ) and thermal comfort are prerequisites for human health and well-being. For their provision, buildings often rely on heating, ventilation, and air conditioning (HVAC) systems, which may lead to higher energy consumption. This directly impacts energy efficiency goals and the linked climate change considerations. The balance between energy use, optimum IAQ and thermal comfort calls for scientifically solid and well-established limit values for exposures experienced by building occupants in indoor spaces, including homes, schools, and offices. The present paper aims to appraise limit values for selected indoor pollutants reported in the scientific literature, and to present how they are handled in international and national guidelines and standards. The pollutants include carbon dioxide (CO 2), formaldehyde (CH 2 O), particulate matter (PM), nitrogen dioxide (NO 2), carbon monoxide (CO), and radon (Rn). Furthermore, acknowledging the particularly strong impact on energy use from HVAC, ventilation, indoor temperature (T), and relative humidity (RH) are also included, as they relate to both thermal comfort and the possibilities to avoid moisture related problems, such as mould growth and proliferation of house dust mites. Examples of national regulations for these parameters are presented, both in relation to human requirements in buildings and considering aspects related to energy saving. The work is based on the Indoor Environmental Quality (IEQ) guidelines database, which spans across countries and institutions, and aids in taking steps in the direction towards a more uniform guidance for values of indoor parameters. The database is coordinated by the Scientific and Technical Committee (STC) 34, as part of ISIAQ, the International Society of Indoor Air Quality and Climate. [ABSTRACT FROM AUTHOR]

Abstract The occurrence and profiles of 15 organophosphate flame retardants/plasticizers (OPFRs) (3 chlorinated [Cl-], 2 aryl-, 5 non-Cl alkyl-, and 5 other types of OPFRs) were investigated in indoor air and dust collected from various microenvironments, including homes in the Albany area of New York State, United States. Concurrent indoor air and dust were collected from floors and window sills at homes and fire stations to investigate the partitioning of OPFRs between the vapor and particulate phases of air and dust. The total concentrations of OPFRs in bulk air (vapor plus particulate phases) were found at several tens to hundreds of ng/m3, with mean concentrations that ranged from 0.12 ng/m3 for tripropyl phosphate (TPP) to 43.8 ng/m3 for tris(1-chloro-2-propyl)phosphate (TCIPP). TCIPP, triethyl phosphate (TEP) and tris(2-butoxyethyl)phosphate (TBOEP) were the predominant compounds found in bulk air, vapor phase, and dust. Among the ten types of microenvironments studied, indoor air samples collected from automobile parts shops contained the highest concentrations of OPFRs (mean: 258 ng/m3), followed by electronics shops, nail salons/shops that sell nail polish, and home construction/interior products shops. Estimated daily intakes of OPFRs via inhalation of air, dermal sorption, and ingestion of dust were 149, 279, and 390 ng/kg bw/day, respectively, which suggested that dust ingestion is an important source of human exposure to OPFRs among the indoor exposure pathways studied. Graphical abstract Unlabelled Image Highlights • 15 OPFRs were measured in indoor air and dust from various microenvironments. • TCIPP was the predominant OPFR found in bulk air. • Automobile-part shops contained the highest concentrations of OPFRs. • Dust ingestion is a major source of human exposure to OPFRs. [ABSTRACT FROM AUTHOR]

Abstract This study investigates the impact of increased levels of indoor air pollution (IAP) caused due to biomass burning in the rural households of Northern India. A comparative assessment of the impact of traditional cookstoves (TCS) and improved cookstoves (ICS) coupled with the characteristics of kitchen was conducted to estimate the PM (PM 10 , PM 2.5 , PM 1), CO/CO 2 concentrations in the micro-environments of kitchen and living area of the households. The study incorporated both extensive and intensive real-time indoor air quality (IAQ) monitoring during the two cooking sessions of the day. The pollutant concentrations were reported in terms of 24-h as well as 8-h (cooking hours including morning and evening meal) averages. Influence of the three types of kitchen characteristics, i.e., enclosed, semi-enclosed and open was also comprehensively analyzed to measure its impact on the IAQ. In addition to this, the IAQ was further used to evaluate the particle size distribution (PSD), respiratory tract deposition and exposure index to assess its impact on health status of the exposed group including women involved in cooking practices. The results of the study highlighted that deployment of ICS would help in improving the IAQ of the kitchen area by resulting in reducing the concentrations of PM 10, PM 2.5, PM 1 and CO by 21–62%, 20–80%, 24–87% and 19–93%, respectively. It was also highlighted that the kitchen characteristics significantly influence the accumulation of air pollutants, demonstrated by the results that the IAQ being worst in the case of enclosed kitchen, resulted in the highest exposure index values. Multivariate regression models to predict PM 1 concentration were also developed for three kitchen categories for both TCS and ICS. Thus, the current study concludes that usage of ICS coupled with efficient designing of the kitchen can improve the overall IAQ of the household along with immense health benefits. Overall, the study emphasized the need of more comprehensive studies to fully assess the association of household air pollution (HAP) and health of individual in the rural settings by considering the toxicity of PM. Graphical abstract Unlabelled Image Highlights • First of its kind comprehensive IAQ study using real-time monitoring, modelling and management under field conditions • Effect of enclosed, semi-enclosed and open kitchens and intervention of two advanced cookstoves were used to measure the IAQ • Intervention resulted in reductions in PM 10, PM 2.5, PM 1 and CO by 21–62%, 20–80%, 24–87% and 19–93%, respectively • IAQ was used to evaluate particle size distribution, respiratory tract deposition and exposure index to assess human health • Women and children are most vulnerable due to exposure to IAQ emitted from biomass burning during cooking hours [ABSTRACT FROM AUTHOR]

Abstract "Dry air" is a major and abundant indoor air quality complaint in office-like environments. The causality of perceived "dry air" and associated respiratory effects continues to be debated, despite no clear definition of the complaint, yet, has been provided. The perception of "dry air" is semantically confusing without an associated receptor but mimics a proto-state of sensory irritation like a cooling sensation. "Dry air" may also be confused with another common indoor air quality complaint "stuffy air", which mimics the sense of no fresh air and of nasal congestion. Low indoor air humidity (IAH) was dismissed more than four decades ago as cause of "dry air" complaints, rather indoor pollutants was proposed as possible exacerbating causative agents during the cold season. Many studies, however, have shown adverse effects of low IAH and beneficial effects of elevated IAH. In this literature overview, we try to answer, "What is perceived "dry air" in indoor environments and its associated causalities. Many studies have shown that the perception is caused not only by extended exposure to low IAH, but also simultaneously with and possibly exacerbated by indoor air pollutants that aggravate the protective mucous layer in the airways and the eye tear film. Immanent diseases in the nose and airways in the general population may also contribute to the overall complaint rate and including other risk factors like age of the population, use of medication, and external factors like the local ambient humidity. Low IAH may be the single cause of perceived "dry air" in the elderly population, while certain indoor air pollutants may come into play among susceptible people, in addition to baseline contribution of nasal diseases. Thus, perceived "dry air" intercorrelates with dry eyes and throat, certain indoor air pollutants, ambient humidity, low IAH, and nasal diseases. Highlights • Perceived dry air is among the most abundant complaints in office-like environments. • Perceived dry air is elicited by low air humidity aggravating eyes, nose and airways. • Perceived dry air may be exacerbated by proto-sensory irritation from air pollutants. • Perceived dry air intercorrelates with low air humidity, eye and nose symptoms. • Age, certain medication, and nasal diseases exacerbate the perception of dry air. [ABSTRACT FROM AUTHOR]

Abstract Indoor air pollution is one of the human health threat problems in the Gulf Cooperation Council (GCC) countries. In these countries, due to unfavorable meteorological conditions, such as elevated ambient temperature, high relative humidity, and natural events such as dust storms, people spend a substantial amount of their time in indoor environments. In addition, production of physical and biological aerosols from air conditioners, cooking activities, burning of Arabian incense, and overcrowding due to pilgrimage programs are common causes of low quality indoor air in this region. Thus, due to infiltration of outdoor sources as well as various indoor sources, people living in the GCC countries are highly exposed to indoor air pollutants. Inhalation of indoor air pollutants causes mortalities and morbidities attributed to cardiorespiratory, pulmonary, and lung cancer diseases. Hence, the aim of this review study is to provide a summary of the major findings of indoor air pollution studies in different microenvironments in six GCC countries. These include characterization of detected indoor air pollutants, exposure concentration levels, source identifications, sustainable building designs and ventilation systems, and the mitigation strategies. To do so, >130 relevant indoor air pollution studies across the GCC countries were critically reviewed. Particulate matters (PM 10 and PM 2.5), total volatile organic compounds (TVOCs), carbon dioxide (CO 2), sulfur dioxide (SO 2), nitrogen dioxide (NO 2), and heavy metals were identified as the reported indoor air pollutants. Apart from them, indoor Radon and bioaerosols were studied only in specific GCC countries. Thus, future studies should also focus on the investigation of emerging indoor air pollutants, such as ultrafine and nanoparticles and their associated health effects. Furthermore, studies on the mitigation of indoor air pollution through the development of advanced air purification and ventilation systems could improve the indoor air quality (IAQ) in the GCC region. Highlights • Infiltration and burning of Bakhour are the main sources of indoor air pollution. • Impacts of building ventilation systems on IAQ were reviewed. • There are limited health impact assessment studies attributed to IAQ in GCC. • IAQ mitigation studies are deficient in the GCC countries. [ABSTRACT FROM AUTHOR]

Abstract Phthalates and organophosphates are ubiquitous indoor semi-volatile organic contaminants (SVOCs) that have been widely used as plasticizers and flame retardants in consumer products. Although many studies have assessed their levels in house dust, only a few used dust samples captured by filters of building heating, ventilation, and air conditioning (HVAC) systems. HVAC filters collect particles from large volumes of air over a long period of time (potentially known) and thus provide a spatially and temporally integrated concentration. This study measured concentrations of phthalates and organophosphates in HVAC filter dust and settled floor dust collected from low-income homes in Texas, United States, in both the summer and winter seasons. The most frequently detected compounds were benzyl butyl phthalate (BBzP), di-(2-ethylhexyl) phthalate (DEHP), di-n-octyl phthalate (DnOP), tris (1-chloro-2-propyl) phosphate (TCIPP), triphenyl phosphate (TPHP), and tris (1,3-dichloroisopropyl) phosphate (TDCIPP). The median level of TCIPP in settled dust was 3- to 180-times higher than levels reported in other studies of residential homes. Significantly higher concentrations were observed in HVAC filter dust as compared to settled dust for most of the frequently detected compounds in both seasons, except for several phthalates in the winter. SVOC concentrations in settled dust in winter were generally higher than in summer, while different seasonality patterns were found for HVAC filter dust. Settled dust samples from homes with vinyl flooring contained significantly higher levels of BBzP and DEHP as compared to homes with other types of floor material. The concentration of DEHP and TDCIPP in settled dust also significantly associated with the presence of carpet in homes. Cleaning activities to remove dust from furniture actually increased the levels of certain compounds in HVAC filter dust, while frequent vacuuming of carpet helped to decrease the concentrations of some compounds in settled dust. Additionally, the size and age of a given house also correlated with the levels of some pollutants in dust. A statistically significant association between DEHP concentration in HVAC filter dust in summer and the severity of asthma in children was observed. These results suggest that HVAC filter dust represents a useful sampling medium to monitor indoor SVOC concentrations with high sensitivity; in contrast, when using settled dust, in addition to consideration of seasonal influences, it is critical to know the sampling location because the type and level of SVOCs may be related to local materials used there. Highlights • Phthalates and organophosphates were detected in HVAC filter dust and settled dust of U.S. low-income homes • Significantly higher SVOC concentrations in HVAC filter dust than in settled dust were observed • Different seasonality patterns were found between SVOC concentrations in settled dust and in HVAC filter dust • Significant associations between SVOC concentrations in dust and building characteristics were observed • Severity of asthma in children was significantly associated with DEHP concentration in HVAC filter dust in summer [ABSTRACT FROM AUTHOR]

Abstract Scientific literature and documents pertaining to the effects of inhalation exposure to carbon dioxide (CO 2) on human health and psychomotor performance were reviewed. Linear physiological changes in circulatory, cardiovascular, and autonomic systems on exposure to CO 2 at concentrations ranging from 500 to 5000 ppm were evident. Human experimental studies have suggested that short-term CO 2 exposure beginning at 1000 ppm affects cognitive performances including decision making and problem resolution. Changes in autonomic systems due to low-level exposure to CO 2 may involve these effects. Further research on the long-term effects of low-level CO 2 exposure on the autonomic system is required. Numerous epidemiological studies indicate an association between low-level exposure to CO 2 beginning at 700 ppm and building-related symptoms. Respiratory symptoms have been indicated in children exposed to indoor CO 2 concentrations higher than 1000 ppm. However, other indoor comorbid pollutants are possibly involved in such effects. In the context of significant linear increase of globally ambient CO 2 concentration caused by anthropogenic activities and sources, reducing indoor CO 2 levels by ventilation with ambient air represents an increase in energy consumption in an air-conditioned building. For the efficient energy control of CO 2 intruding a building from ambient air, the rise of atmospheric CO 2 concentration needs to be urgently suppressed. Highlights • Direct effects of low-level CO 2 exposure on human health should be focused. • Physiological changes occur at CO 2 exposures levels between 500 and 5000 ppm. • Effects on cognitive performance begin at 1000 ppm during short-term exposure. • Comorbid indoor pollutants may be involved in building-related symptoms. • The rise of atmospheric CO 2 concentration needs to be urgently suppressed. [ABSTRACT FROM AUTHOR]

Abstract Epidemiological studies have linked outdoor PM 2.5 concentrations to a range of health effects, although people spend most of the time indoors. To better understand how individuals' exposure vary as they move between different indoor and outdoor microenvironments, our study investigated personal PM 2.5 exposure and exposure intensity of 14 adult volunteers over one week (five weekdays and one weekend), using low-cost personal monitors, recording PM 2.5 concentrations in 5 min intervals. Further, the study evaluated community perception of air pollution exposure during the recruitment and engagement with the volunteers. We found that people with tertiary education across all ages had greater interest in participating, with younger people being interested regardless of the level of education. The derived exposures and exposure intensities differed between weekdays and the weekend due to larger variations in individuals' daily routines. In general, time spent at home and engaged in indoor activities was associated with the highest personal PM 2.5 exposure and exposure intensity on both, week and weekend days, implying the significance of both duration of the exposure and the indoor PM 2.5 concentrations. The results showed no relationship between personal exposures and indoor characteristics of home (ventilation, building age and cooktop), which are expected to be due to the study's small sample size. The observed PM 2.5 > 10 μg m−3 were significantly higher for distances <50 m to the roads for both major and minor roads, and were observed in areas with <16% open space, which were also close to a major road. Highlights • Epidemiological studies do not account for indoor PM 2.5 exposures. • Low-cost sensors provide a good indication of microscale PM 2.5 variations. • The highest personal PM 2.5 exposure was at home both on week and weekend days. • PM 2.5 > 10 μg m−3 were significantly higher at distances < 50 m to the roads. • People with tertiary education had more interest in participating across all ages. [ABSTRACT FROM AUTHOR]

Abstract Since 2007, the nationally representative, cross-sectional Canadian Health Measures Survey (CHMS) has collected detailed health and exposure data from more than 25,000 Canadians, including a wide range of chemical biomarkers analyzed in blood, urine, and environmental media. This article highlights the extent to which the CHMS dataset has been used in the peer-reviewed environmental health literature and opportunities for further expanding usage of the dataset. A literature search (2007–2018) was performed to identify peer-reviewed studies that have made substantive use of the CHMS dataset. Studies were analyzed according to the study type, data usage, populations studied, environmental health themes, citation/publication data, and institutional collaborations. A total of 51 environmental-health related CHMS studies were identified, including studies related to indoor and outdoor air quality, the built environment, and chemical and environmental tobacco smoke exposures. Health indicator data are being increasingly exploited, as is the ability to combine cycle datasets over time. Although these studies covered a range of environmental exposures, many CHMS variables remain underutilized. The CHMS dataset provides a valuable portrait of chemical exposures in Canadians of all ages, linked to a wide variety of health indicators. Many opportunities remain to exploit and expand both the use of the dataset and collaborations between Canadian agencies and domestic and international research institutions. Highlights • To date, 51 publications have used CHMS data to examine environmental exposures and potential impacts on human health. • Data access has been primarily limited to eastern Canadian institutions, and many exposure variables remain underutilized. • Opportunities exist for linkages to external datasets, and for more discrete regional and sub-population analyses. • Further collaboration among federal agencies and academic institutions may serve to broaden data accessibility. [ABSTRACT FROM AUTHOR]

[Display omitted] • The research team examined the effects of indoor environmental variables on absence rates in elementary schools. • Higher classroom ventilation rates significantly reduced illness-related absences. • Higher concentrations of indoor long-term monitored PM 2.5 were significantly associated with increased illness-related absences. • Although mechanically ventilated classrooms had relatively low indoor PM 2.5 , more rigorous control of indoor particles was still beneficial. This study monitored indoor environmental data in 144 classrooms in 31 schools in the Midwestern United States for two consecutive days every fall, winter, and spring during a two-year period; 3,105 pupils attended classrooms where the measurements were conducted. All classrooms were ventilated with mechanical systems that had recirculation; there were no operable exterior windows or doors. The daily absence rate at the student level and demographic data at the classroom level were collected. The overall mean ventilation rate, using outdoor air, was 5.5 L/s per person (the corresponding mean carbon dioxide concentrations were < 2,000 ppm), and the mean indoor PM 2.5 was 3.6 μg/m3. The annual illness-related absence rate at the classroom level was extracted from the student-level absence data and regressed on measured indoor environmental parameters. Significant associations were found. Every 1 L/s per person increase in ventilation rate was associated with a 5.59 decrease in days with absences per year. This corresponds to a 0.15% increase in the annual daily attendance rate. Every additional 1 μg/m3 of indoor PM 2.5 was associated with a 7.37 increase in days with absences per year. This corresponds to a 0.19% decrease in the annual daily attendance rate. No other relationships were significant. Present results agree with the previously demonstrated benefits of reduced absence rates when classroom ventilation is improved and provide additional evidence on the potential benefits of reducing indoor inhalable particles. Overall, reduced absence rates are expected to provide socioeconomic benefits and benefits for academic achievements, while higher ventilation rates and reduced particle levels will also contribute to reduced health risks, including those related to airborne respiratory pathogens. [ABSTRACT FROM AUTHOR]

[Display omitted] • State of the art on real-time sensors for indoor air evaluation is reviewed. • High spatiotemporal resolution data from real-time sensors is favorable for the risk assessment of indoor air pollution. • Challenges including performance, stability and calibration of sensors still remained. • Sensors with high performance, low price, and more target pollutants are expected. People generally spend most of their time indoors, making indoor air quality be of great significance to human health. Large spatiotemporal heterogeneity of indoor air pollution can be hardly captured by conventional filter-based monitoring but real-time monitoring. Real-time monitoring is conducive to change air assessment mode from static and sparse analysis to dynamic and massive analysis, and has made remarkable strides in indoor air evaluation. In this review, the state of art, strengths, challenges, and further development of real-time sensors used in indoor air evaluation are focused on. Researches using real-time sensors for indoor air evaluation have increased rapidly since 2018, and are mainly conducted in China and the USA, with the most frequently investigated air pollutants of PM 2.5. In addition to high spatiotemporal resolution, real-time sensors for indoor air evaluation have prominent advantages in 3-dimensional monitoring, pollution peak and source identification, and short-term health effect evaluation. Huge amounts of data from real-time sensors also facilitate the modeling and prediction of indoor air pollution. However, challenges still remain in extensive deployment of real-time sensors indoors, including the selection, performance, stability, as well as calibration of sensors. In future, sensors with high performance, long-term stability, low price, and low energy consumption are welcomed. Furthermore, more target air pollutants are also expected to be detected simultaneously by real-time sensors in indoor air monitoring. [ABSTRACT FROM AUTHOR]

• A new methodology is provided for low cost source apportionment of household PM. • The characteristics of different rooms are assessed on their air quality impact. • The key role of outdoor air infiltration into the household is quantified. • Daily PM exposure estimates are provided with reference to the WHO guidelines. • Methodology is easily translatable and scalable to different indoor environments. Air quality is one of the most important factors in public health. While outdoor air quality is widely studied, the indoor environment has been less scrutinised, even though time spent indoors is typically much greater than outdoors. The emergence of low-cost sensors can help assess indoor air quality. This study provides a new methodology, utilizing low-cost sensors and source apportionment techniques, to understand the relative importance of indoor and outdoor air pollution sources upon indoor air quality. The methodology is tested with three sensors placed in different rooms inside an exemplar house (bedroom, kitchen and office) and one outdoors. When the family was present, the bedroom had the highest average concentrations for PM 2.5 and PM 10 (3.9 ± 6.8 ug/m3 and 9.6 ± 12.7 μg/m3 respectively), due to the activities undertaken there and the presence of softer furniture and carpeting. The kitchen, while presenting the lowest PM concentrations for both size ranges (2.8 ± 5.9 ug/m3 and 4.2 ± 6.9 μg/m3 respectively), presented the highest PM spikes, especially during cooking times. Increased ventilation in the office resulted in the highest PM 1 concentration (1.6 ± 1.9 μg/m3), highlighting the strong effect of infiltration of outdoor air for the smallest particles. Source apportionment, via positive matrix factorisation (PMF), showed that up to 95 % of the PM 1 was found to be of outdoor sources in all the rooms. This effect was reduced as particle size increased, with outdoor sources contributing >65 % of the PM 2.5 , and up to 50 % of the PM 10 , depending on the room studied. The new approach to elucidate the contributions of different sources to total indoor air pollution exposure, described in this paper, is easily scalable and translatable to different indoor locations. [ABSTRACT FROM AUTHOR]

[Display omitted] Exposure to bioaerosols in indoor environments, especially public venues that have a high occupancy and poor ventilation, is a serious public health concern. However, it remains challenging to monitor and determine real-time or predict near-future concentrations of airborne biological matter. In this study, we developed artificial intelligence (AI) models using physical and chemical data from indoor air quality sensors and physical data from ultraviolet light-induced fluorescence observations of bioaerosols. This enabled us to effectively estimate the bioaerosol (bacteria-, fungi- and pollen-like particle) and 2.5-µm and 10-µm particulate matter (PM 2.5 and PM 10) on a real-time and near-future (≤60 min) basis. Seven AI models were developed and evaluated using measured data from an occupied commercial office and a shopping mall. A long short-term memory model required a relatively short training time and gave the highest prediction accuracy of ∼ 60 %–80 % for bioaerosols and ∼ 90 % for PM on the testing and time series datasets from the two venues. This work demonstrates how AI-based methods can leverage bioaerosol monitoring into predictive scenarios that building operators can use for improving indoor environmental quality in near real-time. [ABSTRACT FROM AUTHOR]

Background More than 90% of the world's population lives in areas where outdoor air pollution levels exceed health-based limits. In these areas, individuals may use indoor air filtration, often on a sporadic basis, in their residences to reduce exposure to respirable particles (PM 2.5 ). Whether this intervention can lead to improvements in health outcomes has not been evaluated. Methods Seventy non-smoking healthy adults, aged 19 to 26 years, received both true and sham indoor air filtration in a double-blinded randomized crossover study. Each filtration session was approximately 13 h long. True and sham filtration sessions were separated by a two-week washout interval. The study was carried out in a suburb of Shanghai. Results During the study period, outdoor PM 2.5 concentrations ranged from 18.6 to 106.9 μg/m 3 , which overlapped with levels measured in Western Europe and North America. Compared to sham filtration, true filtration on average decreased indoor PM 2.5 concentration by 72.4% to 10.0 μg/m 3 and particle number concentration by 59.2% to 2316/cm 3 . For lung function measured immediately after the end of filtration, true filtration significantly lowered airway impedance at 5 Hz (Z 5 ) by 7.1% [95% CI: 2.4%, 11.9%], airway resistance at 5 Hz (R 5 ) by 7.4% [95% CI: 2.4%, 12.5%], and small airway resistance (R 5 -R 20 ) by 20.3% [95% CI: 0.1%, 40.5%], reflecting improved airway mechanics especially for the small airways. However, no significant improvements for spirometry indicators (FEV 1 , FVC) were observed. True filtration also significantly lowered von Willebrand factor (VWF) by 26.9% [95% CI: 7.3%, 46.4%] 24 h after the end of filtration, indicating reduced risk for thrombosis. Stratified analysis in male and female participants showed that true filtration significantly decreased pulse pressure by 3.3% [95% CI: 0.8%, 7.4%] in females, and significantly reduced VWF by 42.4% [95% CI: 17.4%, 67.4%] and interleukin-6 by 22.6% [95% CI: 0.4%, 44.9%] in males. Effect modification analyses indicated that filtration effects in male and female participants were not significantly different. Conclusion A single overnight residential air filtration, capable of reducing indoor particle concentrations substantially, can lead to improved airway mechanics and reduced thrombosis risk. [ABSTRACT FROM AUTHOR]

Multiple chemicals are emitted in residential accommodation. Aggregate Daily Doses (ADD) (ng/kg-bw/d) were estimated for 32 semivolatile organic compounds (SVOCs) of different chemical families that are frequently detected in French dwellings in both air and settled dust. Daily doses were determined using steady-state models for the population, categorized into 11 age groups covering birth to age 30. Three routes of exposure were taken into account: dust ingestion, inhalation (gaseous and particulate phases) and dermal contact with the gaseous phase of air. Contamination levels were preferentially retrieved from large, nationwide representative datasets. A two-dimensional probabilistic approach was used to assess parametric uncertainty and identify the most influential factors. For children aged 2 to 3 years, ADD estimates spanned orders of magnitude, with median values ranging from 8.7 pg/kg-bw/d for 2,2′,3,4,4′-pentabromodiphenylether (BDE 85) to 1.3 μg/kg-bw/d for di-isobutyl phthalate (DiBP). Inhalation, ingestion and dermal pathway contributed at varying levels, and depending on compound, air was the dominant medium for 28 of the 32 compounds (either by inhalation or dermal contact). Indoor exposure estimate variance was mainly driven by indoor contamination variability, and secondarily by uncertainty in physical and chemical parameters. These findings lend support to the call for cumulative risk assessment of indoor SVOCs. [ABSTRACT FROM AUTHOR]

The air quality in the subway metro indoor microenvironment has been of particular public concern. With specific reference to the growing demand of green transportation and sustainable development, subway metro systems have been rapidly developed worldwide in last decades. The number of metro commuters has continuously increased over recent years in metropolitan cities. In some cities, metro system has become the primary public transportation mode. Although commuters typically spend only 30–40 min in metros, the air pollutants emitted from various interior components of metro system as well as air pollutants carried by ventilation supply air are significant sources of harmful air pollutants that could lead to unhealthy human exposure. Commuters' exposure to various air pollutants in metro carriages may cause perceivable health risk as reported by many environmental health studies. This review summarizes significant findings in the literature on air quality inside metro indoor environment, including pollutant concentration levels, chemical species, related sources and health risk assessment. More than 160 relevant studies performed across over 20 countries were carefully reviewed. These comprised more than 2000 individual measurement trips. Particulate matters, aromatic hydrocarbons, carbonyls and airborne bacteria have been identified as the primary air pollutants inside metro system. On this basis, future work could focus on investigating the chronic health risks of exposure to various air pollutants other than PM, and/or further developing advanced air purification unit to improve metro in-station air quality. [ABSTRACT FROM AUTHOR]

The paediatric intensive care unit (PICU) provides care to critically ill neonates, infants and children. These patients are vulnerable and susceptible to the environment surrounding them, yet there is little information available on indoor air quality and factors affecting it within a PICU. To address this gap in knowledge we conducted continuous indoor and outdoor airborne particle concentration measurements over a two-week period at the Royal Children's Hospital PICU in Brisbane, Australia, and we also collected 82 bioaerosol samples to test for the presence of bacterial and viral pathogens. Our results showed that both 24-hour average indoor particle mass (PM 10 ) (0.6–2.2 μg m − 3 , median: 0.9 μg m − 3 ) and submicrometer particle number (PN) (0.1–2.8 × 10 3 p cm − 3 , median: 0.67 × 10 3 p cm − 3 ) concentrations were significantly lower (p < 0.01) than the outdoor concentrations (6.7–10.2 μg m − 3 , median: 8.0 μg m − 3 for PM 10 and 12.1–22.2 × 10 3 p cm − 3 , median: 16.4 × 10 3 p cm − 3 for PN). In general, we found that indoor particle concentrations in the PICU were mainly affected by indoor particle sources, with outdoor particles providing a negligible background. We identified strong indoor particle sources in the PICU, which occasionally increased indoor PN and PM 10 concentrations from 0.1 × 10 3 to 100 × 10 3 p cm − 3 , and from 2 μg m − 3 to 70 μg m − 3 , respectively. The most substantial indoor particle sources were nebulization therapy, tracheal suction and cleaning activities. The average PM 10 and PN emission rates of nebulization therapy ranged from 1.29 to 7.41 mg min − 1 and from 1.20 to 3.96 p min − 1 × 10 11 , respectively. Based on multipoint measurement data, it was found that particles generated at each location could be quickly transported to other locations, even when originating from isolated single-bed rooms. The most commonly isolated bacterial genera from both primary and broth cultures were skin commensals while viruses were rarely identified. Based on the findings from the study, we developed a set of practical recommendations for PICU design, as well as for medical and cleaning staff to mitigate aerosol generation and transmission to minimize infection risk to PICU patients. [ABSTRACT FROM AUTHOR]

[Display omitted] • Sources and dynamics of harmful particles in metro systems are not well characterised. • Fine particulate matter and CO2 were measured in the entire Copenhagen Metro. • High particle concentrations were found despite the system's modernity. • A closed tunnel design and carriage ventilation with tunnel air are the likely causes of the problem. • Sliding doors alone are insufficient for keeping the air clean in carriages and at stations. The Copenhagen Metro comprises four lines, the M1, M2, M3 and M4, with 25 subterranean stations and an additional 14 stations above ground, serving ca. 80 million passengers annually. In this study we measure fine particulate matter (PM 2.5) and carbon dioxide (CO 2) concentrations in stations and in trains across the entire system. In partially underground lines, high PM 2.5 concentrations with an average of 109 μg m−3 are found in below-ground stations. The observed correlation between PM 2.5 concentration and distance between a station and a tunnel exit is attributed to ventilation via the piston effect. The piston effect via tunnel draught relief shafts was therefore found to be relatively limited. Filter samples of particulate matter are analysed using particle-induced X-ray emission and show an iron content of 88.6 % by mass which is quite different from above-ground particulate matter and consistent with particle production by train wheels, rails and brakes. The average concentration measured at the stations of a recently opened (2019) fully underground M3 closed loop line is 168 μg m−3, further demonstrating that while piston effect-driven ventilation is effective in close proximity to tunnel openings, it is relatively limited via tunnel draught relief shafts. Measurements onboard trains show even higher PM 2.5 concentrations and the patterns in CO 2 concentrations suggest carriage ventilation by tunnel air. Ventilation via doors during platform stops caused a drop in observed PM (and CO 2) at stations, but the system is surprisingly polluted despite its recent construction. CO 2 mixing ratios ranged from ambient to around 600 ppm. Measures should be taken to control PM levels using a combination of source control and increased clean air supply of the Copenhagen and other similar metro systems. [ABSTRACT FROM AUTHOR]

Background Cookstove intervention programs have been increasing over the past two (2) decades in Low and Middle Income Countries (LMICs) across the globe. However, there remains uncertainty regarding the effects of these interventions on household air pollution concentrations, personal exposure concentrations and health outcomes. Objectives The primary objective was to determine if household air pollution (HAP) interventions were associated with improved indoor air quality (IAQ) in households in LMICs. Given the potential impact of HAP interventions on health, a secondary objective was to evaluate the effectiveness of HAP interventions to improve health in populations receiving these interventions. Data sources OVID Medline, Ovid Embase, SCOPUS and PubMED were searched from their inception until December 2015 with no restrictions on study design. The WHO Global database of household air pollution measurements and Members' archives were also reviewed together with the reference lists of identified reviews and relevant articles. Study eligibility criteria, participants and intervention We considered randomized controlled trials, or non-randomized control trials, or before-and-after studies; original studies; studies conducted in a LMIC (based on the United Nations Human Development Report released in March 2013 (World Bank, 2013); interventions that were explicitly aimed at improving IAQ and/or health from solid fuel use; studies published in a peer-reviewed journal or student theses or reports; studies that reported on outcomes which was indicative of IAQ or/and health. There was no restriction on the type of comparator (e.g. household receiving plancha vs. household using traditional cookstove) used in the intervention study. Study appraisal and synthesis methods Five review authors independently used pre-designed data collection forms to extract information from the original studies and assessed risk of bias using the Effective Public Health Practice Project (EPHPP). We computed standardized weighted mean difference (SMD) using random-effects models. Heterogeneity was computed using the Q and I2-statistics. We examined the influence of various characteristics on the study-specific effect estimates by stratifying the analysis by population type, study design, intervention type, and duration of exposure monitoring. The trim and fill method was used to assess the potential impact of missing studies. Results Fifty-five studies met our a priori inclusion criteria and were included in the systematic review. Fifteen studies provided 43 effect estimates for our meta-analysis. The largest improvement in HAP was observed for average particulate matter (PM) (SMD = 1.57) concentrations in household kitchens (1.03), followed by daily personal average concentrations of PM (1.18), and carbon monoxide (CO) concentrations in kitchens. With respect to personal PM, significant improvement was observed in studies of children (1.26) and studies monitoring PM for ≥ 24 h (1.32). This observation was also noted in terms of studies of kitchen concentrations of CO. A significant improvement was also observed for kitchen levels of PM in both adult populations (1.56) and in RCT/cohort designs (1.59) involving replacing cookstoves without chimneys. Our findings on health outcomes were inconclusive. Limitations, conclusions and implications of key findings We observed high statistical between study variability in the study-specific estimate. Thus, care should be taken in concluding that HAP interventions - as currently designed and implemented - support reductions in the average kitchen and personal levels of PM and CO. Further, there is limited evidence that current stand-alone HAP interventions yield any health benefits. Post-intervention levels of pollutants were generally still greatly in excess of the relevant WHO guideline and thus a need to promote cleaner fuels in LMICs to reduce HAP levels below the WHO guidelines. Systematic review registration number The review has been registered with PROSPERO (registration number CRD42014009768). [ABSTRACT FROM AUTHOR]

Odorous compounds (odors) like fragrances may cause adverse health effects. To assess their importance by inhalation, we have reviewed how the four major abundant and common airborne fragrances (α-pinene (APN), limonene (LIM), linalool (LIL), and eugenol (EUG)) impact the perceived indoor air quality as odor annoyance, sensory irritation and sensitization in the airways. Breathing and cardiovascular effects, and work performance, and the impact in the airways of ozone-initiated gas- and particle phase reactions products have also been assessed. Measured maximum indoor concentrations for APN, LIM and LIL are close to or above their odor thresholds, but far below their thresholds for sensory irritation in the eyes and upper airways; no information could be traced for EUG. Likewise, reported risk values for long-term effects are far above reported indoor concentrations. Human exposure studies with mixtures of APN and LIM and supported by animal inhalation models do not support sensitization of the airways at indoor levels by inhalation that include other selected fragrances. Human exposure studies, in general, indicate that reported lung function effects are likely due to the perception rather than toxic effects of the fragrances. In general, effects on the breathing rate and mood by exposure to the fragrances are inconclusive. The fragrances may increase the high-frequency heart rate variability, but aerosol exposure during cleaning activities may result in a reduction. Distractive effects influencing the work performance by fragrance/odor exposure are consistently reported, but their persistence over time is unknown. Mice inhalation studies indicate that LIM or its reaction mixture may possess anti-inflammatory properties. There is insufficient information that ozone-initiated reactions with APN or LIM at typical indoor levels cause airway effects in humans. Limited experimental information is available on long-term effects of ozone-initiated reaction products of APN and LIM at typical indoor levels. [ABSTRACT FROM AUTHOR]

Despite the fact that the special characteristics of indoor air pollution make closed environments quite different from outdoor environments, the conceptual ideas for assessing air quality indoors and outdoors are similar. Therefore, the elaboration of International Standards for air quality characterization in view of controlling indoor air quality should resort to this common basis. In this short review we describe the possibilities of standardization of tools dedicated to indoor air quality characterization with a focus on the tools permitting to study the indoor air chemistry. The link between indoor exposure and health as well as the critical processes driving the indoor air quality are introduced. Available International Standards for the assessment of indoor air quality are depicted. The standards comprise requirements for the sampling on site, the analytical procedures, and the determination of material emissions. To date, these standardized procedures assure that indoor air, settled dust and material samples are analyzed in a comparable manner. However, existing International Standards exclusively specify conventional, event-driven target-screening using discontinuous measurement methods for long-lived pollutants. Therefore, this review draws a parallel between physico-chemical processes in indoor and outdoor environments. The achievements in atmospheric sciences also improve our understanding of indoor environments. The community of atmospheric scientists can be both ideal and supporter for researchers in the area of indoor air quality characterization. This short review concludes with propositions for future standardization activities for the chemical characterization of indoor air quality. Future standardization efforts should focus on: (i) the elaboration of standardized measurement methods and measurement strategies for online monitoring of long-lived and short-lived pollutants, (ii) the assessment of the potential and the limitations of non-target screening, (iii) the paradigm shift from event-driven investigations to systematic approaches to characterize indoor environments, and (iv) the development of tools for policy implementation. [ABSTRACT FROM AUTHOR]

Cooking and heating with coal and biomass is the main source of household air pollution in China and a leading contributor to disease burden. As part of a baseline assessment for a household energy intervention program, we enrolled 205 adult women cooking with biomass fuels in Sichuan, China and measured their 48-h personal exposure to fine particulate matter (PM 2.5 ) and carbon monoxide (CO) in winter and summer. We also measured the indoor 48-h PM 2.5 concentrations in their homes and conducted outdoor PM 2.5 measurements during 101 (74) days in summer (winter). Indoor concentrations of CO and nitrogen oxides (NO, NO 2 ) were measured over 48-h in a subset of ~ 80 homes. Women's geometric mean 48-h exposure to PM 2.5 was 80 μg/m 3 (95% CI: 74, 87) in summer and twice as high in winter (169 μg/m 3 (95% CI: 150, 190), with similar seasonal trends for indoor PM 2.5 concentrations (winter: 252 μg/m 3 ; 95% CI: 215, 295; summer: 101 μg/m 3 ; 95% CI: 91, 112). We found a moderately strong relationship between indoor PM 2.5 and CO (r = 0.60, 95% CI: 0.46, 0.72), and a weak correlation between personal PM 2.5 and CO (r = 0.41, 95% CI: − 0.02, 0.71). NO 2 /NO ratios were higher in summer (range: 0.01 to 0.68) than in winter (range: 0 to 0.11), suggesting outdoor formation of NO 2 via reaction of NO with ozone is a more important source of NO 2 than biomass combustion indoors. The predictors of women's personal exposure to PM 2.5 differed by season. In winter, our results show that primary heating with a low-polluting fuel (i.e., electric stove or wood-charcoal) and more frequent kitchen ventilation could reduce personal PM 2.5 exposures. In summer, primary use of a gaseous fuel or electricity for cooking and reducing exposure to outdoor PM 2.5 would likely have the greatest impacts on personal PM 2.5 exposure. [ABSTRACT FROM AUTHOR]

Concentrations of 20 perfluorinated alkyl substances (PFASs) were measured in dust samples from 41 homes in Canada, the Czech Republic, and United States in the spring-summer of 2013. The most frequently detected compounds were perfluorohexanoic acid (PFHxA) and perfluorooctane sulfonate (PFOS). PFOS and perfluorooctanoic acid (PFOA) had the highest concentrations of PFASs in all countries. PFOS median concentrations for the three countries were between 9.1 and 14.1 ng/g, and PFOA medians ranged between 8.2 and 9.3 ng/g. In general, concentrations in North America were higher than in the Czech Republic, which is consistent with usage patterns. No differences were found for perfluorooctane sulfonamides/sulfonamidoethanols (FOSA/Es) levels due to the low number of detections. Homologue profiles suggest that the shift from longer to shorter chain PFASs is more advanced in North America than in Europe. Significant relationships were found among individual homologues and between PFAS concentrations in dust and type of floor, number of people living in the house, and building age. [ABSTRACT FROM AUTHOR]

Human civilization is currently facing two particular challenges: population growth with a strong trend towards urbanization and climate change. The latter is now no longer seriously questioned. The primary concern is to limit anthropogenic climate change and to adapt our societies to its effects. Schools are a key part of the structure of our societies. If future generations are to take control of the manifold global problems, we have to offer our children the best possible infrastructure for their education: not only in terms of the didactic concepts, but also with regard to the climatic conditions in the school environment. Between the ages of 6 and 19, children spend up to 8 h a day in classrooms. The conditions are, however, often inacceptable and regardless of the geographic situation, all the current studies report similar problems: classrooms being too small for the high number of school children, poor ventilation concepts, considerable outdoor air pollution and strong sources of indoor air pollution. There have been discussions about a beneficial and healthy air quality in classrooms for many years now and in recent years extensive studies have been carried out worldwide. The problems have been clearly outlined on a scientific level and there are prudent and feasible concepts to improve the situation. The growing number of publications also highlights the importance of this subject. High carbon dioxide concentrations in classrooms, which indicate poor ventilation conditions, and the increasing particle matter in urban outdoor air have, in particular, been identified as primary causes of poor indoor air quality in schools. Despite this, the conditions in most schools continue to be in need of improvement. There are many reasons for this. In some cases, the local administrative bodies do not have the budgets required to address such concerns, in other cases regulations and laws stand in contradiction to the demands for better indoor air quality, and sometimes the problems are simply ignored. This review summarizes the current results and knowledge gained from the scientific literature on air quality in classrooms. Possible scenarios for the future are discussed and guideline values proposed which can serve to help authorities, government organizations and commissions improve the situation on a global level. [ABSTRACT FROM AUTHOR]

Concentrations of more than 20 brominated flame retardants (FRs), including polybrominated diphenyl ethers (PBDEs) and emerging FRs, were measured in air, dust and window wipes from 63 homes in Canada, the Czech Republic and the United States in the spring and summer of 2013. Among the PBDEs, the highest concentrations were generally BDE-209 in all three matrices, followed by Penta-BDEs. Among alternative FRs, EHTBB and BEHTBP were detected at the highest concentrations. DBDPE was also a major alternative FR detected in dust and air. Bromobenzenes were detected at lower levels than PBDEs and other alternative FRs; among the bromobenzenes, HBB and PBEB were the most abundant compounds. In general, FR levels were highest in the US and lowest in the Czech Republic — a geographic trend that reflects the flame retardants' market. No statistically significant differences were detected between bedroom and living room FR concentrations in the same house ( n = 10), suggesting that sources of FRs are widespread indoors and mixing between rooms. The concentrations of FRs in air, dust, and window film were significantly correlated, especially for PBDEs. We found a significant relationship between the concentrations in dust and window film and in the gas phase for FRs with log K OA values < 14, suggesting that equilibrium was reached for these but not compounds with log K OA values > 14. This hypothesis was confirmed by a large discrepancy between values predicted using a partitioning model and the measured values for FRs with log K OA values > 14. [ABSTRACT FROM AUTHOR]

In the frame of the OFFICAIR project, indoor and outdoor PM 2.5 samples were collected in office buildings across Europe in two sampling campaigns (summer and winter). The ability of the particles to deplete physiologically relevant antioxidants (ascorbic acid (AA), reduced glutathione (GSH)) in a synthetic respiratory tract lining fluid, i.e., oxidative potential (OP), was assessed. Furthermore, the link between particulate OP and the concentration of the PM constituents was investigated. The mean indoor PM 2.5 mass concentration values were substantially lower than the related outdoor values with a mean indoor/outdoor PM 2.5 mass concentration ratio of 0.62 and 0.61 for the summer and winter campaigns respectively. The OP of PM 2.5 varied markedly across Europe with the highest outdoor OP AA m −3 and OP GSH m −3 (% antioxidant depletion/m 3 air) values obtained for Hungary, while PM 2.5 collected in Finland exhibited the lowest values. Seasonal variation could be observed for both indoor and outdoor OP AA m −3 and OP GSH m −3 with higher mean values during winter. The indoor/outdoor OP AA m −3 and OP GSH m −3 ratios were less than one with 4 and 17 exceptions out of the 40 cases respectively. These results indicate that indoor air is generally less oxidatively challenging than outdoors. Correlation analysis revealed that trace elements play an important role in determining OP, in particular, the Cu content. Indoor air chemistry might affect OP since weaker correlations were obtained for indoor PM 2.5 . Our findings also suggest that office workers may be exposed to health relevant PM constituents to a different extent within the same building. [ABSTRACT FROM AUTHOR]

[Display omitted] • Exposure inequality was contrary between ambient and household PM 2.5 exposure. • The poorest experienced the highest PM 2.5 exposure though ambient exposure was low. • Negative concentration index gradually increased indicating a transition towards equality. • Aggressive countermeasures reduced ambient exposures but benefited people disproportionately. • Spontaneous clean household energy transition effectively reduced the exposure inequality. The society has high concerns on the inequality that people are disproportionately exposed to ambient air pollution, but with more time spent indoors, the disparity in the total exposure considering both indoor and outdoor exposure has not been explored; and with the socioeconomical development and efforts in fighting against air pollution, it is unknown how the exposure inequality changed over time. Based on the city-level panel data, this study revealed the Concentration Index ( C ) in ambient PM 2.5 exposure inequality was positive, indicating the low-income group exposed to lower ambient PM 2.5 ; however, the total PM 2.5 exposure was negatively correlated with the income, showing a negative C value. The low-income population exposed to high PM 2.5 associated with larger contributions of indoor exposure from the residential emissions. The total PM 2.5 exposure caused 1.13 (0.63–1.73) million premature deaths in 2019, with only 14 % were high-income population. The toughest-ever air pollution countermeasures have reduced ambient PM 2.5 exposures effectively that, however, benefited the rich population more than the others. The transition to clean household energy sources significantly affected on indoor air quality improvements, as well as alleviation of ambient air pollution, resulting in notable reductions of the total PM 2.5 exposure and especially benefiting the low-income groups. The negative C values decreased from 2000 to 2019, indicating a significantly reducing trend in the total PM 2.5 exposure inequality over time. [ABSTRACT FROM AUTHOR]

[Display omitted] • Determination of parameters of VOC/SVOC from indoor/in-cabin materials are reviewed. • The available key parameters of VOC/SVOC found in the literature are summarized. • The impacts of different factors on VOC/SVOC emission behaviors are discussed. • The spatial scale and time scale of typical methods are compared and discussed. • An approach for indoor and vehicular air quality pre-assessment is introduced. The emissions of volatile organic compounds (VOCs) and semi-volatile organic compounds (SVOCs) from indoor building and vehicle cabin materials can adversely affect human health. Many mechanistic models to predict the VOC/SVOC emission characteristics have been proposed. Nowadays, the main obstacle to accurate model prediction is the availability and reliability of the physical parameters used in the model, such as the initial emittable concentration, the diffusion coefficient, the partition coefficient, and the gas-phase SVOC concentration adjacent to the material surface. The purpose of this work is to review the existing methods for measuring the key parameters of VOCs/SVOCs from materials in both indoor and vehicular environments. The pros and cons of these methods are analyzed, and the available datasets found in the literature are summarized. Some methods can determine one single key parameter, while other methods can determine two or three key parameters simultaneously. The impacts of multiple factors (temperature, relative humidity, loading ratio, and air change rate) on VOC/SVOC emission behaviors are discussed. The existing measurement methods span very large spatial and time scales: the spatial scale varies from micro to macro dimensions; and the time scale in chamber tests varies from several hours to one month for VOCs, and may even span years for SVOCs. Based on the key parameters, a pre-assessment approach for indoor and vehicular air quality is introduced in this review. The approach uses the key parameters for different material combinations to pre-assess the VOC/SVOC concentrations or human exposure levels during the design stage of buildings or vehicles, which can assist designers to select appropriate materials and achieve effective source control. [ABSTRACT FROM AUTHOR]

Daycare centers (DCCs) are where infants and toddlers (0–4 years old) spend the most time besides their homes. Given their higher susceptibility to the effects of air pollutants, as compared to older children and adults, indoor air quality (IAQ) is regarded as an essential parameter to monitor in DCCs. Recent advances in IAQ monitoring technologies have enabled the deployment of low-cost air quality monitors (LCMs) and single sensors (LCSs) to continuously monitor various indoor environments, and their performance testing should also be performed in the intended indoor applications. To our knowledge, there is no study evaluating the application of LCMs/LCSs in DCCs scenarios yet. Therefore, this study is aimed to assess the response of five types of LCMs (previously not tested) and five LCSs to typical DCCs emission activities in detecting multiple IAQ parameters, i.e., particulate matter, carbon dioxide, total volatile organic compounds, temperature, and relative humidity. These LCMs/LCSs were compared to outcomes from research-grade instruments (RGIs). All the experiments were performed in a climate chamber, where three kinds of typical activities (background; arts-and-crafts; cleaning; [in a total of 32 events]) were simulated by recruited subjects at two typical indoor climatic conditions (cool and dry [20 ± 1 °C & 40 ± 10%], warm and humid [26 ± 1 °C & 70 ± 5%]). Results showed that tested LCMs had the ability to capture DCCs activities by simultaneously monitoring multiple IAQ parameters, and LCMs/LCSs revealed a strong correlation with RGIs in most events (R2 values from 0.7 to 1), but, for some events, the magnitude of responses varied widely. Sensirion SCD41, an emerging CO 2 sensor built on the photoacoustic sensing principle, had a more accurate performance than all tested NDIR-based CO 2 sensors/monitors. In general, the study implies that the selection of LCMs/LCSs for a specific application of interest should be based on emission characteristics and space conditions. [ABSTRACT FROM AUTHOR]

Improper natural ventilation practices may deteriorate indoor air quality when in close proximity to roadways, although the intention is often to reduce energy consumption. In this study, we employed a CFD-based air quality model to quantify the impact of traffic-related air pollution on the indoor air quality of a naturally ventilated building. Our study found that the building envelope restricts dispersion and dilution of particulate matter. The indoor concentration in the baseline condition located 10 m away from the roadway is roughly 16–21% greater than that at the edge of the roadway. The indoor flow recirculation creates a well-mixed zone with little variation in fine particle concentration (i.e., 253 nm). For ultrafine particles (< 100 nm), a noticeable decrease in particle concentrations indoors with increasing distance from the road is observed due to Brownian and turbulent diffusion. In addition, the indoor concentration strongly depends on the distance between the roadway and building, particle size, wind condition, and window size and location. A break-even point is observed at D ′ ~ 2.1 (normalized distance from the roadway by the width of the road). The indoor particle concentration is greater than that at the highway where D ′ < 2.1, and vice versa. For new building planning, the distance from the roadway and the ambient wind condition need to be considered at the early design stage whereas the size and location of the window openings, the interior layout, and the placement of fresh air intakes are important to the indoor air quality of existing buildings adjacent to roadways. [ABSTRACT FROM AUTHOR]

This review summarizes the published literature on the presence of polycyclic aromatic hydrocarbons (PAH) in indoor air, settled house dust, and food, and highlights geographical and temporal trends in indoor PAH contamination. In both indoor air and dust, ΣPAH concentrations in North America have decreased over the past 30 years with a halving time of 6.7 ± 1.9 years in indoor air and 5.0 ± 2.3 years in indoor dust. In contrast, indoor PAH concentrations in Asia have remained steady. Concentrations of ΣPAH in indoor air are significantly (p < 0.01) higher in Asia than North America. In studies recording both vapor and particulate phases, the global average concentration in indoor air of ΣPAH excluding naphthalene is between 7 and 14,300 ng/m 3 . Over a similar period, the average ΣPAH concentration in house dust ranges between 127 to 115,817 ng/g. Indoor/outdoor ratios of atmospheric concentrations of ΣPAH have declined globally with a half-life of 6.3 ± 2.3 years. While indoor/outdoor ratios for benzo[ a ]pyrene toxicity equivalents (BaP eq ) declined in North America with a half-life of 12.2 ± 3.2 years, no significant decline was observed when data from all regions were considered. Comparison of the global database, revealed that I/O ratios for ΣPAH (average = 4.3 ± 1.3), exceeded significantly those of BaP eq (average = 1.7 ± 0.4) in the same samples. The significant decline in global I/O ratios suggests that indoor sources of PAH have been controlled more effectively than outdoor sources. Moreover, the significantly higher I/O ratios for ΣPAH compared to BaP eq , imply that indoor sources of PAH emit proportionally more of the less carcinogenic PAH than outdoor sources. Dietary exposure to PAH ranges from 137 to 55,000 ng/day. Definitive spatiotemporal trends in dietary exposure were precluded due to relatively small number of relevant studies. However, although reported in only one study, PAH concentrations in Chinese diets exceeded those in diet from other parts of the world, a pattern consistent with the spatial trends observed for concentrations of PAH in indoor air. Evaluation of human exposure to ΣPAH via inhalation, dust and diet ingestion, suggests that while intake via diet and inhalation exceeds that via dust ingestion; all three pathways contribute and merit continued assessment. [ABSTRACT FROM AUTHOR]

Studies of air pollution effects during pregnancy generally only consider exposure in the outdoor air at the home address. We aimed to compare exposure models differing in their ability to account for the spatial resolution of pollutants, space–time activity and indoor air pollution levels. We recruited 40 pregnant women in the Grenoble urban area, France, who carried a Global Positioning System (GPS) during up to 3 weeks; in a subgroup, indoor measurements of fine particles (PM 2.5 ) were conducted at home (n = 9) and personal exposure to nitrogen dioxide (NO 2 ) was assessed using passive air samplers (n = 10). Outdoor concentrations of NO 2 , and PM 2.5 were estimated from a dispersion model with a fine spatial resolution. Women spent on average 16 h per day at home. Considering only outdoor levels, for estimates at the home address, the correlation between the estimate using the nearest background air monitoring station and the estimate from the dispersion model was high (r = 0.93) for PM 2.5 and moderate (r = 0.67) for NO 2 . The model incorporating clean GPS data was less correlated with the estimate relying on raw GPS data (r = 0.77) than the model ignoring space–time activity (r = 0.93). PM 2.5 outdoor levels were not to moderately correlated with estimates from the model incorporating indoor measurements and space–time activity (r = − 0.10 to 0.47), while NO 2 personal levels were not correlated with outdoor levels (r = − 0.42 to 0.03). In this urban area, accounting for space–time activity little influenced exposure estimates; in a subgroup of subjects (n = 9), incorporating indoor pollution levels seemed to strongly modify them. [ABSTRACT FROM AUTHOR]

Tetrabromobisphenol A (TBBPA) and eight bisphenol analogues (BPs) including bisphenol A (BPA) were determined in 388 indoor (including homes and microenvironments) dust samples collected from 12 countries (China, Colombia, Greece, India, Japan, Kuwait, Pakistan, Romania, Saudi Arabia, South Korea, U.S., and Vietnam). The concentrations of TBBPA and sum of eight bisphenols (ƩBPs) in dust samples ranged from < 1 to 3600 and from 13 to 110,000 ng/g, respectively. The highest TBBPA concentrations in house dust were found in samples from Japan (median: 140 ng/g), followed by South Korea (84 ng/g) and China (23 ng/g). The highest ∑ BPs concentrations were found in Greece (median: 3900 ng/g), Japan (2600 ng/g) and the U.S. (2200 ng/g). Significant variations in BPA concentrations were found in dust samples collected from various microenvironments in offices and homes. Concentrations of TBBPA in house dust were significantly correlated with BPA and ∑ BPs. Among the nine target chemicals analyzed, BPA was the predominant compound in dust from all countries. The proportion of TBBPA in sum concentrations of nine phenolic compounds analyzed in this study was the highest in dust samples from China (27%) and the lowest in Greece (0.41%). The median estimated daily intake (EDI) of ∑ BPs through dust ingestion was the highest in Greece (1.6–17 ng/kg bw/day), Japan (1.3–16) and the U.S. (0.89–9.6) for various age groups. Nevertheless, in comparison with the reported BPA exposure doses through diet, dust ingestion accounted for less than 10% of the total exposure doses in China and the U.S. For TBBPA, the EDI for infants and toddlers ranged from 0.01 to 3.4 ng/kg bw/day, and dust ingestion is an important pathway for exposure accounting for 3.8–35% (median) of exposure doses in China. [ABSTRACT FROM AUTHOR]

Concentrations of a number of organophosphate flame retardants (PFRs) were measured in floor dust collected from UK living rooms (n = 32), cars (n = 21), school and child daycare centre classrooms (n = 28), and offices (n = 61). While concentrations were overall broadly within the range of those reported previously for North America, Japan, and other European countries, median concentrations of TCIPP in all UK microenvironments exceeded those reported elsewhere in the world. Moreover, concentrations of TCIPP and TDCIPP in 2 UK car dust samples were – at 370 μg g − 1 and 740 μg g − 1 respectively – amongst the highest reported globally in indoor dust to date. Consistent with this, concentrations of TDCIPP in dust from UK cars exceed significantly those detected in the other microenvironments studied. Concentrations of EHDPP were shown for the first time to be significantly higher in classroom dust than in samples from other microenvironments. When compared to concentrations of PBDEs determined previously in the classroom dust samples; concentrations of all target PFRs exceeded substantially those of those PBDEs that are the principal constituents of the Penta- and Octa-BDE formulations. Moreover, while mass-based concentrations of BDE-209 exceeded those of most of our target PFRs, they still fell below those of TCIPP and EHDPP. In line with a previous observation in Sweden that indoor air contamination with TNBP was significantly lower in newer buildings; concentrations of TNBP in classroom dust were significantly higher in older compared to more recently-constructed schools. Consistent with the reported extensive use of TCIPP and TDCIPP in polyurethane foam, the highest concentrations of both TCIPP and TDCIPP in the classrooms studied, were observed in rooms containing the highest numbers of foam chairs (n = 31 and 18 respectively). Exposure to PFRs of both adults and young children via ingestion of indoor dust was estimated. While even our high-end exposure estimate for young children was ~ 100 times lower than one previously reported health-based limit (HBLV) value for TCIPP; the margin of safety was only 5-fold when compared to another HBLV for this contaminant. [ABSTRACT FROM AUTHOR]

Halogenated flame-retardants (FRs) are used in a wide array of polymer-containing products. Animal studies and structure-activity modeling exercises suggest that FR exposure may result in detrimental toxicological effects. Workers with extended contact with such polymers (e.g., electronic dismantlers, carpet installers and aircraft personnel) have previously been observed to exhibit elevated body burdens of FRs, e.g., polybrominated diphenyl ethers (PBDEs). Recently, elevated PBDE blood levels were also reported in a non-occupational exposure group, gymnasts. These levels were hypothesized to be related to the large volumes of FR-treated polyurethane foam in gymnastics facilities. To further our understanding of workers' potential exposure, we analyzed FR concentrations in indoor dust and size-fractionated air particulates (respirable (< 4 μm) and inhalable (> 4 μm)) from gymnastic studios. Values were compared to samples from the homes of coaches employed at these facilities. Polyurethane foam blocks (i.e., pit foam) were also analyzed to characterize potential FR sources. FRs examined included those used to flame-retard polyurethane foam: 8 PBDE congeners, two brominated components of Firemaster 550 (2-ethylhexyl 2, 3, 4, 5-tetrabromobenzoate (TBB) and bis(2-ethylhexyl) 3, 4, 5, 6-tetrabromophthalate (TBPH)) and three chlorinated organophosphates (tris(2-chloroethyl) phosphate (TCEP), tris(1-chloro-2-propyl) phosphate (TCPP) and tris(1,3-dichloro-2-propyl) phosphate (TDCPP)). Several additional FRs not used in polyurethane were also evaluated. These have also been detected in indoor dust and air and may also lead to adverse health effects. These include: BDE-183 and its replacement product (1, 2-bis(2, 4, 6-tribromophenoxy) ethane (BTBPE), two congeners of the deca-BDE formulation (BDE-206, -209) and their replacement decabromodiphenyl ethane (DBDPE) and hexabromocyclododecane (α-, β-, γ-HBCD), and tetrabromobisphenol-A (TBBPA)). Pit foam contained multiple FRs at cumulative concentrations of 12,100 to 25,800 μg g − 1 , or 1.2% to 2.6% by weight. TBB and TBPH were the most abundant FRs detected, followed by TDCPP and several PBDEs. The mean total FR burden detected at the gyms was 8.6-fold higher (574 μg g − 1 ) than that observed in the house dust samples (66.8 μg g − 1 ). However, the polyurethane additives TBB and TDCPP were the only FRs that exhibited significantly greater levels ( P < 0.05) in gym than house dust. Mean levels of five FRs (BDE-99, -100, -153, -209 and TDCPP) were also higher in respirable particulates from the gyms than the homes and four FRs (BDE-47, TBB, TBPH and DBDPE) were higher at the homes than the gyms; these differences were not significant ( P > 0.05). Several additional FRs were detected in inhalable particulates; mean levels of BDE-66, -206 and TCPP were higher in the homes and BDE-47, -85, -99, -100, -153, -209, TBB, TBPH, and TDCPP were higher at the gyms. But, only the polyurethane additives i.e., BDE-100, TBB and TDCPP were significantly greater ( P < 0.05) in inhalable particulates from the gyms than at the homes. In conclusion, polyurethane foam collected from gymnastic studios exhibited a variety of FR compositional signatures; likely reflective of changes in FR usage over time and by different manufacturers. FR concentrations and compositional signatures also differed between settled dust, respirable and inhalable particulates between the gyms and homes. Concentrations of FRs used in polyurethane foam were higher in gym air and dust compared to homes, particularly TBB and TDCPP — which were also the primary FRs detected in the pit foam samples. Although these results should be interpreted with caution, as the sample size was small, these findings do suggest that FR concentrations observed in dust and air particulates from the gymnastic studios are further evidence that individuals frequenting these [ABSTRACT FROM AUTHOR]

[Display omitted] • An analytical model is developed to simulate the emissions for both VOCs and SVOCs. • A hybrid optimization method is applied to accurately determine the key parameters. • The effectiveness of the model and measurement method is validated by experiments. • The transition temperature from SVOC-type to VOC-type is observed and determined. The emissions of volatile organic compounds (VOCs) and semi-volatile organic compounds (SVOCs) from indoor materials pose an adverse effect on people's health. In this study, a new analytical model was developed to simulate the emission behaviors for both VOCs and SVOCs under ventilated conditions. Based on this model, we further introduced a hybrid optimization method to accurately determine the key parameters in the model: the initial emittable concentration, the diffusion coefficient, the material/air partition coefficient, and the chamber surface/air partition coefficient (for SVOCs). Experiments for VOC emissions from solid wood furniture were performed to determine the key parameters. We also evaluated the hybrid optimization method with the data of flame retardant emissions from polyisocyanurate rigid foam and VOC emissions from a panel furniture in the literature. The correlation coefficients are high during the fitting process (R2 = 0.92–0.99), demonstrating effectiveness of this method. In addition, we observed that chemical properties could transfer from SVOC-type to VOC-type with the increase of temperature. The transition temperatures from SVOC-type to VOC-type for the emissions of tris(2-chloroethyl) phosphate (TCEP) and tris(1-chloro-2-propyl) phosphate (TCIPP) were determined to be about 45 ℃ and 35 ℃, respectively. The present study provides a unified modelling and methodology analysis for both VOCs and SVOCs, which should be very useful for source/sink characterization and control. [ABSTRACT FROM AUTHOR]

[Display omitted] • Thirdhand smoke (THS) arises from smoking tobacco, cannabis, and illicit substances. • Chemical partitioning and reactions impact the fate and levels of THS indoors. • THS components can react to generate secondary gaseous and particulate pollutants. • THS causes persistent human exposure after smoking has ended. • Pathways of human exposure to THS depend closely on chemical properties. A source of chemical exposure to humans, thirdhand smoke (THS) refers to the contamination that persists indoors following the cessation of a smoking event. The composition of thirdhand smoke depends on the type of substance from which it originates. Although past studies have investigated the effects of tobacco THS on indoor air quality and human health, few have focused on the chemical composition and health impacts of other sources and components of THS. Here we review the state of knowledge of the composition and partitioning behavior of various types of indoor THS, with a focus on THS from tobacco, e-cigarettes, cannabis, and illicit substances (methamphetamine and cocaine). The discussion is supplemented by estimates of human exposure to THS components made with a chemical fate and exposure model. The modeling results show that while very volatile THS compounds (i.e., aromatics) are likely to be taken up by inhalation, highly water-soluble compounds tended to be dermally absorbed. Conversely, minimally volatile THS compounds with low solubility are predicted to be ingested through hand-to-mouth and object-to-mouth contact. [ABSTRACT FROM AUTHOR]

[Display omitted] • Children > 4 years showed slightly higher impacts than younger children. • Differences between urban/rural and winter/spring were significant. • Health impacts from cumulative metal exposures exceeded PM 2.5 impacts. • Metal effects extrapolated from animal studies show the highest uncertainties. To better understand the relation between children health and indoor air quality, we measured the concentrations of fine particulate matter (PM 2.5) and 11 metals (arsenic, cadmium, chromium, copper, iron, manganese, nickel, lead, antimony, selenium, and zinc) from air samples taken during both winter and spring, and focused on urban and rural area kindergartens of the Upper Silesia Region, Poland, typified by the use of fossil fuels for power and heat purposes. We combined related inhalation intake estimates for children and health effects using separate dose–response approaches for PM 2.5 and metals. Results show that impacts on children from exposure to PM 2.5 was 7.5 min/yr, corresponding to 14 μDALY/yr (DALY: disability-adjusted life years) with 95% confidence interval (CI): 0.3–164 min/yr, which is approximately 10 times lower than cumulative impacts from exposure to the metal components in the PM 2.5 fraction of indoor air (median 76 min/yr; CI: 0.2–4.5 × 103 min/yr). Highest metal-related health impacts were caused by exposure to hexavalent chromium. The average combined cancer and non-cancer effects for hexavalent chromium were 55 min/yr, corresponding to 104 μDALY/yr, with CI: 0.5 to 8.0 × 104 min/yr. Health impacts on children varied by season and across urban and rural sites, both as functions of varying PM 2.5 metal compositions influenced by indoor and outdoor emission sources. Our study demonstrates the need to consider indoor environments for evaluating health impacts of children, and can assist decision makers to focus on relevant impact reduction and indoor air quality improvement. [ABSTRACT FROM AUTHOR]

[Display omitted] • Our study indicates abrupt reductions in ambient PM 2.5 from lockdown in China. • The lockdown also led to significant increases in indoor PM 2.5 exposure. • Hundreds of premature deaths were added due to increased household PM 2.5. • Exposure to indoor air pollution is comparable to ambient air pollution exposure. • The lockdown caused an overall increase in integrated population weighted exposure. Ambient and household air pollution are found to lead to premature deaths from all-cause or cause-specific death. The national lockdown measures in China during COVID-19 were found to lead to abrupt changes in ambient surface air quality, but indoor air quality changes were neglected. In this study, we aim to investigate the impacts of lockdown measures on both ambient and household air pollution as well as the short-term health effects of air pollution changes. In this study, an up-to-date emission inventory from January to March 2020 in China was developed based on air quality observations in combination with emission-concentration response functions derived from chemical transport modeling. These emission inventories, together with the emissions data from 2017 to 2019, were fed into the state-of-the-art regional chemistry transport model to simulate the air quality in the North China Plain. A hypothetical scenario assuming no lockdown effects in 2020 was also performed to determine the effects of the lockdown on air quality in 2020. A difference-to-difference approach was adopted to isolate the effects on air quality due to meteorological conditions and long-term decreasing emission trends by comparing the PM 2.5 changes during lockdown to those before lockdown in 2020 and in previous years (2017–2019). The short-term premature mortality changes from both ambient and household PM 2.5 changes were quantified based on two recent epidemiological studies, with uncertainty of urban and rural population migration considerations. The national lockdown measures during COVID-19 led to a reduction of 5.1 µg m−3 in ambient PM 2.5 across the North China Plain (NCP) from January 25th to March 5th compared with the hypothetical simulation with no lockdown measures. However, a difference-to-difference method showed that the daily domain average PM 2.5 in the NCP decreased by 9.7 µg m−3 between lockdown periods before lockdown in 2020, while it decreased by 7.9 µg m−3 during the same periods for the previous three-year average from 2017 to 2019, demonstrating that lockdown measures may only have caused a 1.8 µg m−3 decrease in the NCP. We then found that the integrated population-weighted PM 2.5 , including both ambient and indoor PM 2.5 exposure, increased by 5.1 µg m−3 during the lockdown periods compared to the hypothetical scenario, leading to additional premature deaths of 609 (95% CI: 415–775) to 2,860 (95% CI: 1,436–4,273) in the short term, depending on the relative risk chosen from the epidemiological studies. Our study indicates that lockdown measures in China led to abrupt reductions in ambient PM 2.5 concentration but also led to significant increases in indoor PM 2.5 exposure due to confined indoor activities and increased usages of household fuel for cooking and heating. We estimated that hundreds of premature deaths were added as a combination of decreased ambient PM 2.5 and increased household PM 2.5. Our findings suggest that the reduction in ambient PM 2.5 was negated by increased exposure to household air pollution, resulting in an overall increase in integrated population weighted exposure. Although lockdown measures were instrumental in reducing the exposure to pollution concentration in cities, rural areas bore the brunt, mainly due to the use of dirty solid fuels, increased population density due to the large-scale migration of people from urban to rural areas during the Chinese New Year and long exposure time to HAP due to restrictions in outdoor movement. [ABSTRACT FROM AUTHOR]

Abstract: Different household insecticide applications via two electric vaporizers emitting transfluthrin were realized in a full-scale experimental room under controlled air exchange rate conditions. On-line high-time resolved measurements of the gas-phase concentrations of the active substance during and immediately after the spreading periods were performed with a High Sensitivity Proton-Transfer-Reaction Mass Spectrometer (HS-PTR-MS). Experimental and modelled data from the ConsExpo 4.0 software were also compared to evaluate the sources of differences. Different application scenarios were also compared. Averaged inhaled concentrations over 1h, 1week, and 5months were estimated to be 8.3, 1.8, and 1.8μg.m−3, respectively. Corresponding margins of exposures range from 1000 to 10,000, claiming for the absence of effect. Dermal and dust ingestion pathways, although roughly estimated, seems being non-negligible. This claims for a more in-depth integrated risk assessment. [Copyright &y& Elsevier]

• Solid fuel combustion in indoor stoves is the highest risk of inhalation exposure sources for humans. • Higher emission values and variability in field-based results need to be evaluated. • Emission testing protocols significantly affect stove performance. • Quantitative fugitive fractions are imperative for evaluating indoor air quality. • Studies are needed to characterize dynamic changes in indoor air pollution. A large population does not have access to modern household energy and relies on solid fuels such as coal and biomass fuels. Burning of these solid fuels in low-efficiency home stoves produces high amounts of multiple air pollutants, causing severe air pollution and adverse health outcomes. In evaluating impacts on human health and climate, it is critical to understand the formation and emission processes of air pollutants from these combustion sources. Air pollutant emission factors (EFs) from indoor solid fuel combustion usually highly vary among different testing protocols, fuel-stove systems, sampling and analysis instruments, and environmental conditions. In this critical review, we focus on the latest developments in pollutant emission factor studies, with emphases on the difference between lab and field studies, fugitive emission quantification, and factors that contribute to variabilities in EFs. Field studies are expected to provide more realistic EFs for emission inventories since lab studies typically do not simulate real-world burning conditions well. However, the latter has considerable advantages in evaluating formation mechanisms and variational influencing factors in observed pollutant EFs. One main challenge in field emission measurement is the suitable emission sampling system. Reasons for the field and lab differences have yet to be fully elucidated, and operator behavior can have a significant impact on such differences. Fuel properties and stove designs affect emissions, and the variations are complexly affected by several factors. Stove classification is a challenge in the comparison of EF results from different studies. Lab- and field-based methods for quantifying fugitive emissions, as an important contributor to indoor air pollution, have been developed, and priority work is to develop a database covering different fuel-stove combinations. Studies on the dynamics of the combustion process and evolution of air pollutant formation and emissions are scarce, and these factors should be an important aspect of future work. [ABSTRACT FROM AUTHOR]

• Individual ultrafine particle (UFP) number concentration in subway workers over 6 weeks. • Application of Bayesian spline method for concentration medelling. • Integration of contextual information (Job, Day, Station, Environment, Event). • Insights on UFP exposure determinants for workers and passengers. Air pollution in subway environments is a growing concern as it often exceeds WHO recommendations for indoor air quality. Ultrafine particles (UFP), for which there is still no regulation nor a standardized exposure monitoring method, are the strongest contributor to this pollution when the number concentration is used as exposure metric. We aimed to assess the real-time UFP number concentration in the personal breathing zone (PBZ) of three types of underground Parisian subway professionals and analyze it using a novel Bayesian spline approach. Consecutively, we investigated the effect of job, week day, subway station, worker location, and some further events on UFP number concentrations. The data collection procedure originated from a longitudinal study and lasted for a total duration of 6 weeks (from October 7 to November 15, 2019, i.e. two weeks per type of subway professionals). Time-series were built from the real-time particle number concentration (PNC) measured in the PBZ of professionals during their work-shifts. Complementarily, contextual information expressed as Station, Environment, and Event variables were extracted from activity logbooks completed for every work-shift. A Bayesian spline approach was applied to model the PNC within a Bayesian framework as a function of the mentioned contextual information. Overall, the Bayesian spline method suited a real-time personal PNC data modeling approach. The model enabled estimating the differences in UFP exposure between subway professionals, stations, and various locations. Our results suggest a higher PNC closer to the subway tracks, with the highest PNC on subway station platforms. Studied event and week day variables had a lesser influence. It was shown that the Bayesian spline method is suitable to investigate individual exposure to UFP in underground subway settings. This method is informative for better documenting the magnitude and variability of UFP exposure, and for understanding the determinants in view of further regulation and control of this exposure. [ABSTRACT FROM AUTHOR]

Abstract: Within-house and within-room spatial temporal variability in PBDE contamination of indoor dust may influence substantially the reliability of human exposure assessments based on single point samples, but have hitherto been little studied. This paper reports concentrations of PBDEs 17, 28, 47, 49, 66, 85, 99, 100, 153, and 154 in indoor dust samples (n=112) from two houses in Birmingham, UK. To evaluate within-house spatial variability, four separate rooms were sampled in house 1 and two separate rooms sampled in house 2. Up to four different 1m2 areas in the same room were sampled to evaluate within-room spatial variability, and for all studied areas, samples were taken for eight consecutive months to evaluate temporal and seasonal variability. Concentrations of ΣPBDEs in individual samples from house 1 varied between 21 and 280ngg−1; while the range of concentrations in house 2 was 20–1000ngg−1. This indicates that where and when a sample is taken in a house can influence substantially the contamination detected. In one room, concentrations of PBDEs in an area located close to putative PBDE sources exceeded substantially those in an area 2m away, with marked differences also observed between two areas in another room. Substantial within-room spatial differences in PBDE concentrations were not discernible in the other rooms studied. Concentrations of PBDEs in the majority of rooms within the same houses were not markedly different between rooms. Nevertheless, large differences were observed between PBDE concentrations detected in two rooms in the same house in both houses studied. In one instance, this is hypothesised to be attributable to the presence of a carpet in one room and bare wooden floor in another, but firm conclusions cannot be drawn. Within-room temporal (month-to-month) variability was substantial (relative standard deviations for ΣPBDEs=15–200%). In some rooms, the introduction and removal of putative sources like a TV and a bed, appeared to exert a discernible influence on PBDE concentrations. PBDE concentrations in spring and summer were not markedly different from those observed in autumn and winter. Possible dilution of PBDE concentrations in dust at higher dust loadings (g dust per m2 floor surface) was investigated in a small number of rooms, but no firm evidence of such dilution was evident. [Copyright &y& Elsevier]

Abstract: Data on polybrominated diphenyl ether (PBDE) and hexabromocyclododecane (HBCD) concentrations from Stockholm, Sweden, indoor microenvironments were combined with information from detailed questionnaires regarding the sampling location characteristics, including furnishing and equipment present. These were used to elucidate relationships between possible flame-retarded sources and the contaminant concentrations found in air and dust. Median concentration ranges of ΣPenta-, ΣOcta-, ΣDecaBDE and HBCD from all microenvironments were 19–570, 1.7–280, 29–3200 and <1.6–2pg/m3 in air and 22–240, 6.1–80, 330–1400 and 45–340ng/g in dust, respectively. Significant correlations were found between concentrations of some PBDEs and HBCD in air and/or dust and the presence of electronic/electrical devices, foam furniture, PUF mattresses and synthetic bed pillows in, as well as floor area and construction year of the microenvironment. Car interiors were a source to indoor air in dealership halls. Using median and maximum concentrations of ΣPenta-, ΣOcta-, ΣDecaBDE and HBCD in air and dust, adult and toddler (12–24months) intakes from inhalation and dust ingestion were estimated. Toddlers had higher estimated intakes of ΣPenta-, ΣDecaBDE and HBCD (7.8, 43, 7.6ng/d, respectively) from dust ingestion than adults (5.8, 38, 6.0ng/d, respectively). Air inhalation in offices was also an important exposure pathway for ΣPenta-, ΣOcta- and ΣDecaBDE in adults. For ΣPentaBDE and HBCD, air inhalation and dust ingestion play minor roles when compared to previously published Swedish dietary intakes (median exposures). However, in worst case scenarios using maximum concentrations, dust ingestion may represent 77 and 95% of toddler intake for ΣPentaBDE and HBCD, respectively. [Copyright &y& Elsevier]