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Researchers from the Korea Institute of Oriental Medicine have conducted a study on the effects of the ethyl acetate fraction of chestnut honey (EACH) on cognitive impairment and neurotoxicity. The study found that EACH administration reversed cognitive decline in mice and alleviated cell viability decrease induced by glutamate exposure in neuronal cells. The research suggests that EACH has potential therapeutic value in mitigating oxidative stress-induced neurotoxicity and cognitive decline. For more information, the full article is available in the journal Antioxidants. [Extracted from the article]

Research conducted at the Heilongjiang Academy of Agricultural Sciences in China has focused on the treatment of Bovine Viral Diarrhea/mucosal Disease (BVD-MD) using traditional Chinese medicine (TCM). The study identified five key Chinese medicines and 206 targets associated with BVD-MD, revealing the potential of TCM in inhibiting the Bovine viral diarrhea virus (BVDV). Molecular dynamics analysis showed that quercetin, a core component of Chinese medicine, exhibited stability with key target genes, ultimately affecting viral expression. The research concluded that the mechanism of BVDV inhibition by core Chinese medicines is closely related to specific signaling pathways and protein interactions. [Extracted from the article]

A recent study conducted at Chengdu University of Traditional Chinese Medicine explores the Maillard reaction and its application in the processing of traditional Chinese medicine and food. The research delves into the mechanism of the reaction, factors influencing it, and techniques for extracting Maillard reaction products (MRPs). The study highlights the diverse physiological functions of MRPs, such as antioxidant, antibacterial, and anti-inflammatory effects, while also noting potential harmful constituents. Various methods for separating and purifying MRPs are compared, emphasizing the need for careful consideration in specific applications. The research offers valuable insights for industries involved in food and traditional Chinese medicinal material processing, with implications for healthcare and clinical practice. [Extracted from the article]

A recent study conducted by Heilongjiang University in Harbin, China, explored the mechanisms of Goupi Plaster in treating Knee Osteoarthritis (KOA) using integrated skin metabolomics and network pharmacology. The research found that GP administration improved cartilage structure, decreased inflammatory factors, normalized metabolites, and regulated skin lipid metabolism, neurotransmitters, and the purinergic signaling pathway. This study sheds light on the potential benefits of traditional Chinese medicine in managing KOA. [Extracted from the article]

Researchers at Shenyang Pharmaceutical University in Liaoning, China, have developed advancements in screening systems for active ingredients in Traditional Chinese Medicines (TCMs) using the ligand fishing technique. This method offers high specificity, efficiency, simplicity, and throughput compared to traditional screening techniques. The research highlights the potential of these new methodologies to expedite drug development and improve effectiveness. The study has been peer-reviewed and provides valuable insights into the future of TCM research and drug discovery. [Extracted from the article]

A recent study from Shanghai University of Traditional Chinese Medicine explores the dual nature of DNA damage caused by chemotherapy and the potential of traditional Chinese medicine (TCM) to reduce its toxicity. TCM is shown to be effective in alleviating side effects of chemotherapy due to its natural and non-toxic properties. The research highlights key mechanisms of DNA damage by chemotherapeutics and specific TCM herbs that may help reduce these side effects, providing valuable insights for clinical and basic research. [Extracted from the article]

Researchers from the Chinese Peoples' Liberation Army General Hospital conducted a study on the effects of Traditional Chinese Medicine (TCM) wet compresses on pain, inflammation, and quality of life in patients with soft tissue injuries. The study identified key ingredients and targets of TCM wet compresses, comparing the treatment with Voltaalin ointment. Results showed that TCM wet compress patches effectively reduced pain, inflammation, and improved quality of life in patients with soft tissue injuries, suggesting it as a promising alternative treatment. The research was published in the American Journal of Translational Research and has been peer-reviewed. [Extracted from the article]

A recent study from Bashkir State Medical University highlights the potential benefits of traditional Chinese medicine (TCM) in treating autoimmune diseases of the nervous system. The research emphasizes the importance of complementary and alternative medicine as a valuable resource in preventing and managing these conditions. TCM, which includes acupuncture, herbal medicine, dietetics, and physical exercises, is shown to have positive clinical outcomes when used alongside conventional medical treatments. The study underscores the significance of integrating traditional and complementary medicine approaches in healthcare, particularly in addressing autoimmune diseases. [Extracted from the article]

A study conducted by the University of Calicut in Kerala, India, explored the cytotoxic effects of Anamirta cocculus leaf extracts on various cancer cell lines and normal cell lines. The research found that the ethyl acetate extract of A. cocculus exhibited potent anticancer activity against ovarian and colorectal cancer cell lines while showing low toxicity towards normal human keratinocyte cells. Molecular docking studies revealed interactions with key apoptotic proteins, suggesting the potential of compounds like epoxylathyrol as promising anticancer drug candidates. The research has been peer-reviewed and offers insights into the anticancer potential of A. cocculus. [Extracted from the article]

Researchers at Peking University in Guangdong, China, have highlighted the role of Traditional Chinese Medicine (TCM) in drug discovery and personalized medicine. They emphasize the importance of data standardization and the use of AI algorithms in advancing TCM modernization and patient care. The application of AI in TCM shows promise in enhancing chemical component identification, drug discovery, personalized treatment, and pharmacological action elucidation. This research underscores the potential benefits of integrating AI technologies with TCM practices for continued progress and innovation in the field. [Extracted from the article]

A recent study from Chalmers University of Technology explores the diverse activities and mechanisms of the acylphloroglucinol antibiotic rhodomyrtone, derived from the rose myrtle plant. Rhodomyrtone demonstrates antibacterial, antiviral, antiplasmodial, immunomodulatory, and anticancer properties, with a unique mechanism of action that affects cellular processes. While showing promise as a therapeutic agent, challenges such as resistance development and potential mammalian cell toxicity require further investigation. The research provides valuable insights into the potential applications of rhodomyrtone beyond its antibacterial properties. [Extracted from the article]

A study conducted in Xinjiang, China, explored the potential mechanisms of Zigongding (ZGD), a traditional Chinese medicine, in treating HPV-induced Cervical Intraepithelial Neoplasia (CIN). The research integrated network pharmacology and experimental validation to identify active ingredients, targets, and molecular mechanisms of ZGD. The study found that ZGD may modulate the estrogen receptor 1 (ESR1) to treat CIN, providing a novel insight into the therapeutic potential of ZGD in CIN treatment. This research was supported by the Natural Science Foundation of Xinjiang Uygur Autonomous Region and has been peer-reviewed. [Extracted from the article]

A recent study conducted by Hangzhou Medical College in China explores the potential neuroprotective effects of flavonoids derived from traditional Chinese medicine. Neurodegenerative diseases pose significant challenges to drug development and clinical treatment due to their complex pathological mechanisms. The study focuses on six common flavonoids, including quercetin and rutin, and examines their characteristics, mechanisms, and key signaling pathways. The findings highlight the neuroprotective properties of these compounds, such as anti-inflammatory and anti-oxidative stress effects, regulation of autophagy balance, inhibition of apoptosis, and promotion of neuronal regeneration. The research aims to provide a reference for further studies and the development of neuroprotective drugs. [Extracted from the article]

Researchers from Prince of Songkla University in Thailand have conducted a study on the effects of Quercus infectoria gall ethanolic extract (QIG) on wound healing in fibroblasts. The study found that QIG exhibited potent antioxidant activity and reduced cytotoxicity caused by hydrogen peroxide. It also reduced intracellular reactive oxygen species production and inflammation-related gene expression. The researchers concluded that QIG has potential therapeutic applications in wound healing by regulating oxidative stress and inflammatory response. This information is available in the journal article "Quercus infectoria Gall Ethanolic Extract Accelerates Wound Healing through Attenuating Inflammation and Oxidative Injuries in Skin Fibroblasts." [Extracted from the article]

A recent study conducted by researchers from Hong Kong Baptist University explores the use of Traditional Chinese Medicine (TCM) for managing Irritable Bowel Syndrome (IBS). The study aims to bridge the knowledge gap by evaluating existing guidelines, reviewing TCM practices, and providing contemporary treatment recommendations. The researchers identified different TCM patterns for IBS patients and recommended 22 CM prescriptions for managing IBS. This comprehensive study combines guidelines with real clinical practices, offering enhanced treatment choices for IBS patients and improving their quality of life. [Extracted from the article]

A recent study conducted by researchers at Kasetsart University in Thailand explored the potential biological properties of Caesalpinia sappan L. heartwood extracts. The study investigated the effects of three different extraction methods on the brazilin content and biological activities of the extract. The results showed that the maceration and reflux methods produced high levels of brazilin and total phenolic contents, as well as exhibiting excellent antioxidant and antimicrobial activities. Additionally, the macerated extract demonstrated anti-inflammatory properties. These findings suggest that Caesalpinia sappan L. heartwood extract has the potential to be a valuable source of biological components. [Extracted from the article]

Researchers at the Korea Institute of Oriental Medicine have conducted a study on the pharmacological action of Aconitum carmichaeli Debeaux (ACD), a herb used in therapies. Using bioinformatics and transcriptomics, they predicted and verified the organ in which ACD predominantly acts. Their findings showed that ACD primarily acts in the brain rather than the intestine. This multi-bioinformatics-based approach has the potential to be used in future studies on drug efficacy and side effects. [Extracted from the article]

A recent report discusses research conducted by the Korea Institute of Oriental Medicine on the traditional herbal formula Sayeok-tang (SYT). The researchers used ultrahigh-performance liquid chromatography coupled with quadrupole (UPLC-Q)-Orbitrap-MS to screen the phytochemicals of SYT and identified a total of 42 compounds. They also developed an analytical method to quantify 24 of these compounds. The study concluded that this method is highly promising for the comprehensive quality control of SYT. The research provides valuable insights into the composition and potential therapeutic benefits of this traditional herbal formula. [Extracted from the article]

A recent study conducted by the China Academy of Chinese Medical Sciences explores the potential of traditional Chinese medicine (TCM) in treating hematologic malignancies, such as leukemia and multiple myeloma. The study focuses on a newly identified form of cell death called ferroptosis, which is characterized by lipid peroxidation and elevated iron levels. The researchers suggest that TCM may modulate hematologic malignancies through the ferroptosis pathway, making it a potential therapeutic target. The study aims to enhance treatment efficacy by understanding the mechanisms of ferroptosis and the role of TCM in preventing and treating hematologic malignancies. [Extracted from the article]

A study conducted by researchers at Guangxi University of Chinese Medicine in China explores the use of Traditional Chinese Medicine (TCM) in the treatment of postmenopausal osteoporosis (PMOP). The study analyzes 141 TCM formulas used to treat PMOP and identifies core medications and their therapeutic effects. The researchers also conduct a network pharmacological analysis to identify active ingredients, targets of action, and signaling pathways involved in TCM treatment of PMOP. The study provides a foundation for further research and data support for TCM treatment of PMOP. [Extracted from the article]

A study conducted by the Korea Institute of Oriental Medicine has provided new insights into the mechanisms of traditional herbal medicine. The research focused on the combination therapies used in East Asia, which have shown high efficacy and minimal side effects for specific diseases. The study aimed to address the complexity of these therapies by constructing drug-induced transcriptome data for herbal medicines and analyzing them with various omics databases. The resulting dataset, called KORE-Map 1.0, aims to aid in the discovery of new therapeutic targets and indications for incurable diseases. [Extracted from the article]

A recent study conducted by researchers at Chonnam National University in South Korea explored the potential cognitive benefits of Agastache rugosa, a traditional Asian herbal medicine primarily used for digestive problems. The study found that an extract of A. rugosa demonstrated significant antioxidant and anti-inflammatory effects, as well as improved memory performance in mice with scopolamine-induced memory impairment. The extract also showed modulation of the cholinergic system and increased hippocampal neurogenesis, suggesting its potential use as a cognitive enhancer. This research provides valuable insights into the potential therapeutic applications of A. rugosa in addressing cognitive decline. [Extracted from the article]

A new study from Shandong University of Traditional Chinese Medicine explores the potential of traditional Chinese medicine (TCM) as a complementary therapy for depression. The study focuses on the role of neuroplasticity, which refers to the brain's ability to adapt and change, in the development of depression. The researchers systematically reviewed recent literature on neuroplasticity in depression and analyzed the effects of TCM on neuroplasticity in antidepressant treatment. The study concludes by discussing the limitations of current research and the potential application of TCM in regulating neuroplasticity in antidepressant research. [Extracted from the article]

Researchers from Wuhan University in China have conducted a study on acute kidney injury (AKI) using bioinformatics and traditional Chinese medicine. The study aimed to understand the molecular mechanisms underlying AKI and explore Chinese herbal medicines for its management. The researchers analyzed gene expression data and identified key genes associated with AKI. They also identified traditional Chinese medicines, such as Danshen, Renshen, Danggui, and Sanqi, that could potentially treat AKI. The study provides new insights for clinical interventions and establishes a basis for further research in this area. [Extracted from the article]

A study conducted by researchers from Shandong First Medical University and Shandong Academy of Medical Sciences explores the effectiveness of acupuncture therapy in improving nasolabial folds and marionette lines, which are common signs of aging. The study compares two different acupuncture techniques: traditional acupuncture and acupuncture using needle knives. The results show that the acupuncture technique using needle knives is more effective in reducing wrinkle depth, although it may cause slightly more pain. The study suggests that acupuncture therapy can be a noninvasive and long-lasting facial cosmetic technique for those seeking rejuvenation. [Extracted from the article]

A recent study conducted at Princess Margaret Hospital in Hong Kong, People's Republic of China, focused on Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), a potentially life-threatening condition caused by certain drugs. The study specifically examined a case of DRESS induced by Traditional Chinese Medicine. The researchers emphasized the importance of a thorough drug history and a high level of suspicion for early diagnosis. The study has been peer-reviewed and published in the Hong Kong Journal of Paediatrics. [Extracted from the article]

Researchers at Guangzhou Medical University in China have conducted a study on the potential of Traditional Chinese Medicines (TCM) in combating drug-resistant Staphylococcus aureus (S. aureus). The study used molecular dynamics simulations to analyze the interactions between TCM compounds and the NorA protein, which is involved in drug resistance. The compounds piperine, demethoxycurcumin, and tectorigenin showed potential inhibitory activity against NorA, forming hydrogen bonds and hydrophobic contacts with key ionizable residues. This research provides insights into the potential of TCM in addressing drug resistance in S. aureus. [Extracted from the article]

Researchers from Nanjing University of Chinese Medicine have conducted a study on the use of traditional Chinese medicine (TCM) for the treatment of acute rhinosinusitis. They developed a nanodrug called BP-C@PEG, which is loaded with curcumin, and found that it exhibited good anti-inflammatory action for the treatment of acute rhinosinusitis. The nanodrug showed promising therapeutic efficiency in alleviating cilium injury and the recruitment of inflammatory cells in the nasal mucosa of mice. This study provides a potential approach for acute rhinosinusitis therapy using TCM in the biomedical field. [Extracted from the article]

A recent report from Guangdong University of Technology in China discusses the use of polymer nanocarriers to enhance the delivery of active ingredients from Traditional Chinese Medicines (TCMs). TCMs have been used for thousands of years and contain bioactive compounds with therapeutic potential. However, their clinical application is often limited due to challenges such as poor solubility and low bioavailability. The review explores the use of different types of polymer nanocarriers, such as micelles and hydrogels, to improve the solubility, stability, and bioavailability of TCM components. The researchers highlight the transformative potential of polymer nanocarriers in revolutionizing TCM delivery, ensuring safety and efficacy in a modern medical context. [Extracted from the article]

A recent study conducted by researchers at North University of China explores the use of nanoparticles for combination therapy in the treatment of colorectal cancer (CRC). The study highlights the potential of traditional Chinese medicine in the treatment of CRC due to its high efficiency and low toxicity. However, the poor water solubility and low bioavailability of active ingredients in traditional Chinese medicine limit their efficacy. The researchers developed a nanoplatform called SA@PDA-FA NPs, which combines polydopamine (PDA) and honokiol (HK) with folic acid (FA) for tumor targeting and efficient drug delivery. The combination therapy demonstrated significant tumor growth inhibition without adverse effects. This research provides a green strategy for the development of oncology combination therapies. [Extracted from the article]

A recent study conducted by researchers at Chengdu University explores the pharmacological activity and clinical application of traditional Chinese medicine ginger. The study found that different types of ginger possess distinct strengths and inclinations when it comes to effectiveness and medicinal applications. Fresh ginger is more hydrating and skilled at heating the Middle-jiao, while dried ginger has the ability to alleviate coldness and diarrhea. The research emphasizes the need to modernize ginger by incorporating traditional Chinese medicine theory and utilizing modern drug research technology. [Extracted from the article]

Researchers from Beijing University of Chinese Medicine have conducted a study on the pharmacological effects and targets of Citri Grandis Exocarpium (CGE), a traditional Chinese medicine commonly used for cough and indigestion. Using a combination of artificial intelligence, cell experiments, and virtual screening, the researchers found that CGE has antiallergic effects and promotes bile, blood lipid regulation, cardiotonics, diuresis, and antiarrhythmia. They also identified mitogen-activated protein kinase 14 (MAPK14) and matrix metalloprotease 9 (MMP9) as key potential targets of CGE. This study provides new insights into the pharmacological effects and mechanisms of traditional Chinese medicine. [Extracted from the article]

A new report from Anhui University of Chinese Medicine discusses the pharmacological properties and medicinal value of albiflorin, a principal monoterpene glycoside found in traditional Chinese medicine recipes. The report highlights albiflorin's anti-inflammatory effects in various disease models and its efficient absorption, distribution, and elimination in the body. While comprehensive toxicological studies are lacking, the report suggests that albiflorin shows promise as a therapeutic agent for inflammation-related diseases. Further research is needed to fully explore its medical potential. [Extracted from the article]

A recent study conducted by researchers at the Korea Institute of Oriental Medicine focused on the development of an analytical method to simultaneously quantify 13 compounds in Yeokwisan (YWS), an herbal medicine prescription used to treat reflux esophagitis. The researchers used high-performance liquid chromatography-photodiode array detection (HPLC-PDA) and ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) to analyze the compounds and explore their antioxidant effects. The study found that baicalein and baicalin, two compounds in YWS, exhibited significant antioxidant activity. This research provides valuable insights into the composition and potential therapeutic effects of YWS. [Extracted from the article]

A recent study on traditional Chinese medicine (TCM) suggests that the field will experience significant changes and advancements in the coming years. The study highlights the potential impact of modern biological and information technologies, such as artificial intelligence, on the development of TCM. Researchers predict that by 2035, TCM will merge with modern medicine, leading to a more contemporary and open research and development model. This integration is expected to provide substantial support for treating a wider range of diseases. [Extracted from the article]

A recent study conducted by researchers from the Korea Institute of Oriental Medicine explored the potential benefits of a combined herbal medicine (CHM) in treating amyotrophic lateral sclerosis (ALS). The study found that the CHM treatment improved movement and reduced motor neuron loss in mice with ALS. Additionally, the treatment exhibited anti-inflammatory and antioxidant activities and regulated autophagy in the muscles and spinal cord. These findings suggest that CHM may effectively delay disease progression in ALS. Further research is needed to explore the potential of herbal medicine in treating neurodegenerative diseases like ALS. [Extracted from the article]

Researchers at Southern Medical University in Guangzhou, China have conducted experiments to investigate the antioxidant, antimicrobial, and anti-inflammatory effects of Liriodendron chinense leaves, which are commonly used in traditional Chinese medicine. The study found that the leaves have significant antioxidant, antimicrobial, and anti-inflammatory properties. Three compounds found in the leaves, fragransin B2, liriodendritol, and rhamnocitrin, were identified as potential key active constituents that may work together to treat inflammatory-related disorders. The research suggests that Liriodendron chinense leaves have potential healing properties for inflammatory diseases. [Extracted from the article]

A recent report from the Korea Institute of Oriental Medicine (KIOM) discusses research on the herpes simplex virus 1 (HSV-1). The study found that ginsenoside Rg5, an activator of the oxidative stress regulator Nrf2, has antiviral effects against HSV-1. The virus generates reactive oxygen species (ROS) that impact viral replication and induce chronic inflammation. However, treatment with ginsenoside Rg5 inhibited ROS signaling and reduced inflammatory cytokines through Nrf2 induction. These findings suggest that ginsenoside Rg5 could be a potential therapeutic agent for HSV-1-induced neuroinflammation. [Extracted from the article]

A recent study conducted by researchers at the Korea Institute of Oriental Medicine explored the risk of stroke through the use of personalized medicine. The study focused on the role of genetic characteristics and metabolic traits in the Korean population. By applying the Mendelian randomization method, the researchers found that different constitutional types were associated with varying risks of stroke, particularly cardioembolic stroke. These findings emphasize the importance of personalized medicine in assessing disease risk based on an individual's constitutional type. [Extracted from the article]

Researchers from Guangdong University of Technology have developed a flexible and dissolving microneedle patch for sleep-aid intervention in traditional Chinese medicine (TCM). The patch, which carries herbal extracts, aims to provide an alternative to drug therapy and non-drug therapy methods for insomnia. The study found that the patch was effective in improving sleep quality, as indicated by increased ratios of low-frequency brain wave energies to high-frequency brain wave energies. This research offers a novel approach to sleep-aid intervention using TCM and may provide a safer alternative to Western medicine for insomnia treatment. [Extracted from the article]

Researchers from the Beijing Institute of Technology have developed a new colorimetric method for detecting and quantifying total triterpenoids in traditional Chinese medicine. By incorporating specific colorants and sulfuric acid, the sensitivity and accuracy of the detection process were significantly improved. The method offers advantages such as high sensitivity, short usage time, low solvent usage, and low equipment costs. This research not only provides a reliable method for detecting total triterpenes in traditional Chinese medicine but also offers a rapid detection tool for on-site testing and large-scale screening, contributing to the modernization of traditional Chinese medicine research, quality control, and drug development. [Extracted from the article]

A recent study from Zunyi Medical University in China discusses the advancements and challenges in pharmacokinetic and pharmacodynamic research on traditional Chinese medicine (TCM) saponins. The study highlights the difficulty in selecting representative indicators for pharmacokinetic studies due to the complex nature of TCM. The low bioavailability and short half-life of saponins limit their clinical application, but novel delivery systems and drug combinations show promise in enhancing their effectiveness. The research emphasizes the need for rigorous clinical validation and provides a theoretical basis for new clinical drugs. [Extracted from the article]

A recent research study conducted by the Korea Institute of Oriental Medicine focused on the therapeutic modes of action of terpenes found in Poria cocos F.A Wolf (PC). The study used molecular docking, drug-induced transcriptome analysis, and diffusion network analysis to confirm the pharmacological mechanism of PC terpenes. The results of the study suggest that future pharmacological mechanism analysis should consider complementary docking and transcriptomics, as well as diffusion network analysis. The study provides evidence for the broad mode of action of PC and highlights the potential of natural complex compounds in pharmacological research. [Extracted from the article]

Researchers at Shenyang Pharmaceutical University in China have conducted a study on the anti-inflammatory effects of darutigenol (DL), an active compound found in traditional Chinese medicine used to treat rheumatoid arthritis (RA). The researchers discovered that DL can scavenge reactive oxygen species and reduce the secretion of proinflammatory cytokines. They also developed a drug delivery system using ROS-responsive prodrug nanoassemblies, which showed superior therapeutic effects compared to DL alone. This study provides insights into the mechanism of DL and offers a potential strategy for the application and development of active compounds in traditional Chinese medicine. [Extracted from the article]

A case report published in the journal Medicine discusses the successful treatment of a patient with Primary Sjogren's syndrome using traditional Chinese herbal medicine. The patient, a 56-year-old woman, had been experiencing chronic dry eye and mouth for over 10 years and had previously tried other treatments without success. After 8 weeks of treatment with specific herbal decoctions, the patient reported significant improvement in her symptoms. The report highlights the potential effectiveness of traditional Chinese medicine in treating Sjogren's syndrome and emphasizes the importance of tailoring treatment to individual patients. [Extracted from the article]

A recent study conducted by researchers at the Shanghai University of Traditional Chinese Medicine explored the mitochondrial protective effects of certain compounds found in the Bu-Shen-JianPi formula (BSJP), a traditional Chinese medicine. The study used a neuroblastoma cell line to examine the effects of icariin, naringenin, kaempferol, and formononetin on mitochondrial protection and anti-ferroptotic activity. The results showed that these compounds have potential clinical importance in the treatment of nervous system diseases and hypoxia-related symptoms. The research has been peer-reviewed and published in the International Journal of Clinical Pharmacology and Therapeutics. [Extracted from the article]

A recent study conducted at Longhua Hospital Shanghai University of Traditional Chinese Medicine has highlighted the advancements in understanding traditional Chinese medicine (TCM) treatment mechanisms through the use of network formulaology and network pharmacology. The researchers developed TCMNPAS, a comprehensive analysis platform that integrates these two approaches to investigate the compatibility characteristics of TCM formulas and their potential molecular mechanisms. TCMNPAS offers various functions for automated analysis, including prescription mining, molecular docking, network pharmacology analysis, and visualization. This platform enables researchers to analyze herbal prescription data, identify core herbs and formulas, and explore therapeutic targets for disease treatment. TCMNPAS is available as an open-source R package and can be accessed freely. [Extracted from the article]

Researchers at the Korea Institute of Oriental Medicine have developed a method for assessing the quality of Bopyeo-tang (BPT), a traditional herbal formula used to treat respiratory diseases. The method uses ultra-performance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS) to separate and analyze eighteen marker compounds in BPT. The method was found to be accurate and efficient, with coefficients of determination ranging from 0.9991 to 0.9996. This method will be used for quality control of BPT preparations. [Extracted from the article]

A recent report from the Second Affiliated Hospital highlights the importance of Traditional Chinese Medicine (TCM) in treating diseases. However, traditional research methods have limitations in evaluating clinical efficacy and identifying active ingredients. To address this, a new strategy called Chinmedomics has been proposed, which combines systems biology, serum pharmacochemistry, and bioinformatics to evaluate TCM efficacy. The article reviews the progress of Chinmedomics and its potential for modernizing and internationalizing TCM. This research was supported by the National Natural Science Foundation of China and the Heilongjiang Province Key Research and Development Plan. [Extracted from the article]

A recent study conducted by researchers at Beijing University of Chinese Medicine investigated the protective effects of Jinteng Qingbi granules (JTQBG), a traditional Chinese medicine formulation, on rheumatoid arthritis (RA) in rats. The study found that JTQBG had a significant therapeutic effect on the rats by reducing inflammation, synovial hyperplasia, cartilage erosion, and bone destruction. The researchers also identified potential molecular mechanisms, including the suppression of the NF-kB pathway and the regulation of serum metabolite disorders. These findings suggest that JTQBG may be an effective treatment for RA. [Extracted from the article]