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Researchers from Shizuoka University in Hamamatsu, Japan have conducted a study on the potential for bioethanol production from paper sludge (PS) obtained from paper mills. The researchers found that waste-paper-containing PS can be used as a raw material for bioethanol production, as the global waste paper utilization rate has increased. They used subcritical water pretreatment to selectively decompose enzyme inhibitors in the PS without generating other enzyme inhibitors, resulting in a significant increase in bioethanol yield. The researchers concluded that this method could enable the use of large amounts of PS as ethanol feedstock in the future. [Extracted from the article]

A new study conducted in Chandigarh, India, introduces a novel rotating paper disk (RPD) device for the analysis of a wide range of analytes related to obesity, fitness, and wellness. The RPD device utilizes cellulose paper and 1-octanol to simplify the sample preparation process. The method was optimized using various factors and was found to be linear and precise within a certain range. The proposed method has also been successfully applied in forensic toxicology case work. The study also evaluated the whiteness and blueness of the method using specific algorithms and software. [Extracted from the article]

Researchers from Nanjing Forestry University in the People's Republic of China have developed a multifunctional air filter paper with flame retardant, antibacterial, and hydrophobic properties. The paper was prepared using chemical treatment with pre-synthesized N, N-biguanide-diethyl phosphonic acid (AGDEPA) and octadecyl trichlorosilane (OTS). The air filter paper demonstrated self-extinguishing behavior, met industry standards for flame retardant materials, and showed high efficiency in killing E. coli and S. aureus bacteria. The addition of mercerized fibers also improved the air permeability of the filter paper. This research has been peer-reviewed and published in the Journal of Environmental Chemical Engineering. [Extracted from the article]

A recent study conducted by researchers at Shandong University of Technology in Zibo, China, has developed a new sensor platform for detecting hydrogen peroxide (H2O2). The researchers used a combination of polypyrrole and paper-derived carbon to create a non-enzymatic sensor that demonstrated high sensitivity and stability. The sensor's performance was attributed to the unique structure of the polypyrrole/paper-derived carbon composite, which prevented the self-dimerization of hemin, a key component of the sensor. This research has potential applications in various fields, including health and medicine. [Extracted from the article]

Researchers from the University of Jinan in Guangzhou, China, have developed a series of 5-amino-1 H-pyrazole-4-carboxamide derivatives as novel pan-FGFR covalent inhibitors for the treatment of various cancers. These inhibitors target both wild-type and gatekeeper mutant FGFRs, addressing the issue of drug resistance. The representative compound 10h demonstrated strong activity against FGFRs and effectively suppressed the proliferation of lung and gastric cancer cells. The study provides a promising avenue for the development of anticancer drugs targeting FGFRs. [Extracted from the article]

A report from the School of Pharmaceutical Sciences in Shandong, China discusses the development of a new method for extracting compounds with desired pharmaceutical functions from natural products. The researchers synthesized an imidazole-functionalized paper membrane that demonstrated selectivity in extracting gallic acid from pomegranate peel. The optimal membrane solid-phase extraction method allowed for easy quantitative analysis with a limit of detection of 0.1 ng mL(-1). This work provides a novel approach to preparing extraction membranes and offers an analytical method for natural products. [Extracted from the article]

A recent study conducted by researchers at Shanghai University in China has developed a simple and affordable paper analytical device for on-site detection of lead (Pb). The device utilizes a visual distance-based method to detect Pb by inhibiting the catalytic activity of G-quadruplex/hemin DNAzyme induced by potassium (K+). The device has been optimized to detect Pb concentrations ranging from 0.02 μM to 50 μM, with a lowest detection limit of 1 nM. The researchers believe that this device could be particularly useful for detecting heavy metal ions in resource-limited areas. [Extracted from the article]

A recent study conducted at the University of Mosul in Iraq has explored the structural and pharmacological diversity of heterocycles fused on a 6,7-coumarin framework. Coumarin derivatives are versatile compounds that have shown potential for various biological activities and medical applications. The researchers reviewed 189 relevant papers released between 2000 and mid-2023 to provide a comprehensive understanding of the pharmacological potential, structure-function correlations, natural sources, and synthetic techniques of these compounds. The findings of this study may contribute to the development of biologically active leads for medicinal chemists in the future. [Extracted from the article]

A study conducted by researchers at South China Normal University in Guangzhou, China, has focused on the development of a flexible wearable sweat sensor for real-time monitoring and noninvasive sampling. The sensor uses surface-enhanced Raman spectroscopy (SERS) to analyze the constituents in human sweat and assess individual physiological states and potential related diseases. The researchers validated the sensor's molecular permeation and enrichment capability and demonstrated its wearability and capability for detecting sweat biomarkers. The study concludes that SERS wearable technology provides a new approach for real-time detection, disease diagnosis, and personalized health monitoring. [Extracted from the article]

A new report from the University Department of Life Sciences and Public Health discusses the potential of personalized medicine (PM) to revolutionize healthcare by tailoring treatments to individual patients based on their data. The report highlights the need for the seamless integration of innovative technologies and collaboration between the European Union (EU) and China in the field of personalized medicine. A Delphi survey was conducted to identify key priorities for the implementation of personalized medicine, including data interoperability, standards, security measures, international partnerships, cost-effectiveness, and value assessment. The effective implementation of new technologies in personalized medicine is crucial for advancing healthcare systems in both Europe and China. [Extracted from the article]

A recent study conducted by researchers at the Harbin Institute of Technology in Shenzhen, China, has developed a paper-based microfluidic sensor array for the discrimination of tetracycline antibiotics. The sensor array utilizes lanthanide metal-carbon quantum dots composite ink and inkjet printing technology to create a portable and cost-effective device. The platform successfully differentiated six different tetracycline antibiotics and demonstrated its practicality in real samples. This research has potential applications in disease diagnosis, food safety, and environmental contamination. [Extracted from the article]

Researchers at the University of Karachi in Pakistan have developed a highly stable and sensitive colorimetric sensor using silver nanoparticles (AgNPs) for the detection of omeprazole at trace levels. The sensor combines AgNPs-based paper technology with smartphone technology for real-time analysis of omeprazole. The sensor demonstrated high stability, sensitivity, and versatility, making it suitable for on-site and point-of-care omeprazole detection in various samples. This research provides a promising solution for real-time omeprazole analysis with potential applications beyond pharmaceutical formulations. [Extracted from the article]

Researchers at National Tsing-Hua University in Hsinchu, Taiwan have developed a new microfluidic chip with a paper-based aptamer-sandwich assay for the detection of HNP 1, a biomarker for periprosthetic joint infections (PJI), in synovial fluid. The assay demonstrates high selectivity and affinity for target molecules and offers rapid, cost-effective, and highly sensitive detection of HNP 1. It has a wide dynamic range and can detect levels as low as 0.5 mg L-1. The researchers believe that this assay has the potential to enhance PJI diagnosis in clinical settings. [Extracted from the article]

Hence, this work employed activated carbon prepared from freely available paper mill sewage sludge for removing chloramphenicol (CAP) and methylene blue (MB)." Keywords: Pulau Pinang; Malaysia; Asia; Antibiotics; Antidotes; Antiinfectives; Chloramphenicol; Chloramphenicol Therapy; Drugs and Therapies; Health and Medicine; Hydrocarbons; Methylene Blue; Methylene Blue Therapy; Nitro Compounds; Nitrobenzenes; Ophthalmic Antiinfectives; Ophthalmic Preparations; Pharmaceuticals; Phenothiazines; Propylene Glycols; Topical Agents; Urinary Antiinfectives EN Pulau Pinang Malaysia Asia Antibiotics Antidotes Antiinfectives Chloramphenicol Chloramphenicol Therapy Drugs and Therapies Health and Medicine Hydrocarbons Methylene Blue Methylene Blue Therapy Nitro Compounds Nitrobenzenes Ophthalmic Antiinfectives Ophthalmic Preparations Pharmaceuticals Phenothiazines Propylene Glycols Topical Agents Urinary Antiinfectives 2341 2341 1 11/06/23 20231110 NES 231110 2023 NOV 10 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on Drugs and Therapies - Ophthalmic Antiinfectives. [Extracted from the article]

A report from the Department of Chemistry in Kerala, India discusses research on sustainability and material science. The study focuses on the synthesis of cellulose nanocrystals (CNCs) from waste paper and the development of a chitosan-CNC (CS-CNCs) composite. The CS-CNCs composite demonstrated enhanced mechanical properties, biodegradability, antibacterial activity, and photocatalytic degradation of dyes. The research suggests that this composite could be used in wastewater treatment, self-cleaning surfaces, environmental remediation, and packaging, offering a sustainable and economical solution for environmental cleanup and material innovation. [Extracted from the article]

A recent study conducted at Christ University in Karnataka, India, has discovered a novel method for synthesizing a benzimidazole derivative called 2-(4-methoxyphenyl)-1 H-benzo[ d ]imidazole. The researchers used ferrocenyl aniline as a catalyst in combination with electropolymerized thiophene-3-acetic acid on carbon fiber paper, resulting in a highly efficient electrocatalyst. The synthesis was performed using a three-electrode system and yielded a 91% product yield, which was then characterized using various techniques. The researchers concluded that this environmentally friendly synthesis method is significant due to its high yield and pharmacological importance. [Extracted from the article]

Researchers from Shanghai Jiao Tong University have conducted a study on pancreatic cancer, specifically focusing on the role of N6-methyladenosine (m6A) modification in the pathogenesis of pancreatic ductal adenocarcinoma (PDAC). The study found that the expression of methyltransferase-like 16 (METTL16), a critical m6A methyltransferase, is significantly diminished in PDAC. METTL16 was found to regulate the expression of DVL2, a protein involved in Wnt/beta-catenin signaling, through m6A modification. The study suggests that METTL16 could be a potential therapeutic target for PDAC treatment. [Extracted from the article]

Lanzhou, People's Republic of China, Asia, Antibacterials, Antibiotics, Antimicrobials, Drugs and Therapies, Health and Medicine Keywords: Lanzhou; People's Republic of China; Asia; Antibacterials; Antibiotics; Antimicrobials; Drugs and Therapies; Health and Medicine EN Lanzhou People's Republic of China Asia Antibacterials Antibiotics Antimicrobials Drugs and Therapies Health and Medicine 3296 3296 1 10/30/23 20231103 NES 231103 2023 NOV 3 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on Drugs and Therapies - Antibiotics. [Extracted from the article]

Keywords for this news article include: Xiamen, People's Republic of China, Asia, Cancer, Carcinomas, Drugs and Therapies, Epidemiology, Health and Medicine, Nasopharyngeal Carcinoma, Oncology, Xiamen University. Keywords: Xiamen; People's Republic of China; Asia; Cancer; Carcinomas; Drugs and Therapies; Epidemiology; Health and Medicine; Nasopharyngeal Carcinoma; Oncology EN Xiamen People's Republic of China Asia Cancer Carcinomas Drugs and Therapies Epidemiology Health and Medicine Nasopharyngeal Carcinoma Oncology 1004 1004 1 05/02/23 20230505 NES 230505 2023 MAY 2 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Current study results on Oncology - Nasopharyngeal Carcinoma have been published. [Extracted from the article]

Wuxi, People's Republic of China, Asia, Carboxylic Acids, Central Nervous System Agents, Drugs and Therapies, Fatty Acid Derivative Anticonvulsants, Health and Medicine, Organic Chemicals, Pentanoic Acids, Pharmaceuticals, Valproic Acid, Valproic Acid Therapy Keywords: Wuxi; People's Republic of China; Asia; Carboxylic Acids; Central Nervous System Agents; Drugs and Therapies; Fatty Acid Derivative Anticonvulsants; Health and Medicine; Organic Chemicals; Pentanoic Acids; Pharmaceuticals; Valproic Acid; Valproic Acid Therapy EN Wuxi People's Republic of China Asia Carboxylic Acids Central Nervous System Agents Drugs and Therapies Fatty Acid Derivative Anticonvulsants Health and Medicine Organic Chemicals Pentanoic Acids Pharmaceuticals Valproic Acid Valproic Acid Therapy 1029 1029 1 09/19/23 20230922 NES 230922 2023 SEP 22 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- New research on Drugs and Therapies - Fatty Acid Derivative Anticonvulsants is the subject of a report. [Extracted from the article]

According to the news editors, the research concluded: "In addition, the compounds with strong inhibitory effects on OCT2 identified in this study may be potential candidates for clinical use to mitigate cisplatin-induced nephrotoxicity." Keywords: Wonju; South Korea; Asia; Alkylating Agents; Antineoplastics; Chlorine Compounds; Cisplatin Therapy; Drugs and Therapies; Health and Medicine; Kidney; Nephrology; Nitrogen Compounds; Pharmaceuticals; Platinum Compounds EN Wonju South Korea Asia Alkylating Agents Antineoplastics Chlorine Compounds Cisplatin Therapy Drugs and Therapies Health and Medicine Kidney Nephrology Nitrogen Compounds Pharmaceuticals Platinum Compounds 2563 2563 1 08/28/23 20230901 NES 230901 2023 SEP 1 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Fresh data on Drugs and Therapies - Cisplatin Therapy are presented in a new report. All 10 compounds alleviated cisplatin-induced cytotoxicity in cells expressing OCT2, even though the magnitude of the effects varied depending on the functional moieties in each position. [Extracted from the article]

For the MID patients with extrapulmonary cryptococcosis, the mortality is high and the initial treatment should follow the regimen for SID patients. Keywords: Nanjing; People's Republic of China; Asia; Bacterial Infections and Mycoses; China; Cryptococcosis; Drugs and Therapies; Health and Medicine; Mycoses EN Nanjing People's Republic of China Asia Bacterial Infections and Mycoses China Cryptococcosis Drugs and Therapies Health and Medicine Mycoses 2131 2131 1 08/07/23 20230808 NES 230808 2023 AUG 11 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Research findings on Bacterial Infections and Mycoses - Cryptococcosis are discussed in a new report. However, in extrapulmonary cryptococcosis patients with MID, the mortality was signifi-cantly higher than that in IC [62.5% vs. 0.0% (IC)], and similar to SID patients [62.5% vs. 59.3% (SID)]. [Extracted from the article]

This paper can reduce the white pollution caused by non-degradable single-use plastic packaging products. Keywords: Jinan; People's Republic of China; Asia; Obesity Fitness and Wellness; Drugs and Therapies EN Jinan People's Republic of China Asia Obesity Fitness and Wellness Drugs and Therapies 2103 2103 1 03/23/23 20230310 NES 230310 2023 MAR 10 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Research findings on Obesity, Fitness and Wellness are discussed in a new report. Jinan, People's Republic of China, Asia, Obesity Fitness and Wellness, Drugs and Therapies. [Extracted from the article]

Keywords for this news article include: Shandong, People's Republic of China, Asia, Biological Factors, Emerging Technologies, Health and Medicine, Heme, Hemin, Nanocomposites, Nanotechnology, Porphyrins, Qufu Normal University. Keywords: Shandong; People's Republic of China; Asia; Biological Factors; Emerging Technologies; Health and Medicine; Heme; Hemin; Nanocomposites; Nanotechnology; Porphyrins EN Shandong People's Republic of China Asia Biological Factors Emerging Technologies Health and Medicine Heme Hemin Nanocomposites Nanotechnology Porphyrins 1778 1778 1 04/10/23 20230414 NES 230414 2023 APR 14 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- A new study on Nanotechnology - Nanocomposites is now available. [Extracted from the article]

According to the news reporters, the research concluded: "The therapeutic range of radiation dose detection, facile fabrication and implementation of this radiochromic film can be potentially translated into different radiotherapy clinical applications." New Delhi, India, Asia, Life Science, Drugs and Therapies, Health and Medicine, Radiotherapy Keywords: New Delhi; India; Asia; Life Science; Drugs and Therapies; Health and Medicine; Radiotherapy EN New Delhi India Asia Life Science Drugs and Therapies Health and Medicine Radiotherapy 2095 2095 1 04/03/23 20230407 NES 230407 2023 APR 7 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- New research on Life Science is the subject of a report. [Extracted from the article]

Keywords: Chandigarh; India; Asia; Obesity Fitness and Wellness; Drugs and Therapies EN Chandigarh India Asia Obesity Fitness and Wellness Drugs and Therapies 2023 FEB 3 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Data detailed on Obesity, Fitness and Wellness have been presented. Chandigarh, India, Asia, Obesity Fitness and Wellness, Drugs and Therapies. [Extracted from the article]

Keywords: Mosul; Iraq; Asia; Anticancer Agents; Antioxidants; Cancer; Cancer Therapy; Drugs and Therapies; Health and Medicine; Oncology; Phenols; Protective Agents EN Mosul Iraq Asia Anticancer Agents Antioxidants Cancer Cancer Therapy Drugs and Therapies Health and Medicine Oncology Phenols Protective Agents 470 470 1 11/06/23 20231110 NES 231110 2023 NOV 7 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on Drugs and Therapies - Anticancer Agents. Mosul, Iraq, Asia, Anticancer Agents, Antioxidants, Cancer, Cancer Therapy, Drugs and Therapies, Health and Medicine, Oncology, Phenols, Protective Agents. [Extracted from the article]

Keywords: Haryana; India; Asia; Genomics and Genetics; Drugs and Therapies; Semicarbazides; Semicarbazones; Sulfur Compounds; Thiosemicarbazones EN Haryana India Asia Genomics and Genetics Drugs and Therapies Semicarbazides Semicarbazones Sulfur Compounds Thiosemicarbazones 2278 2278 1 08/14/23 20230818 NES 230818 2023 AUG 18 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on Genomics and Genetics. Keywords for this news article include: Haryana, India, Asia, Genomics and Genetics, Drugs and Therapies, Semicarbazides, Semicarbazones, Sulfur Compounds, Thiosemicarbazones, Guru Jambheshwar University. Haryana, India, Asia, Genomics and Genetics, Drugs and Therapies, Semicarbazides, Semicarbazones, Sulfur Compounds, Thiosemicarbazones. [Extracted from the article]

A recent study conducted at the University of Mosul in Iraq has provided new information about drug research. The study focused on coumarin hybrids, which are compounds derived from phytocoumarins and have various biological activities. These compounds have the potential to be used in the development of novel pharmaceutical medicines for complex diseases such as cancer, Alzheimer's disease, and cardiovascular disorders. The researchers conducted a comprehensive review of relevant papers and aimed to create highly efficient coumarin hybrid molecules for medicinal purposes. The study has been peer-reviewed and more information can be obtained from the University of Mosul. [Extracted from the article]

A recent report from the Indian Institute for Technology in Kharagpur, India discusses the use of nanoclays and graphene in thermoplastic nanocomposites for packaging applications. These nanofillers have been found to improve the physical, mechanical, thermal, and barrier properties of packaging materials, making them suitable for use in industries such as automotive, pharmaceutical, food packaging, and electronics. The review paper provides an overview of the preparation, characterization, and properties of these nanocomposites, as well as their potential applications in food and electronic packaging. The research was supported by the Board of Research in Nuclear Sciences (BRNS) and has been peer-reviewed. [Extracted from the article]

A report from QILU University of Technology in Shandong, China discusses the use of food-grade nanoparticles in food preservation and material development. The report focuses on the use of Pickering emulsions, which are stabilized by solid particles, and their potential applications in paper coating and enhancing food shelf life. The researchers found that the use of octadecenylsuccinic anhydride modified gamma-cyclodextrin metal-organic frameworks in the emulsions improved paper water resistance and fruit preservation. The study also highlighted the antimicrobial properties of these frameworks, suggesting potential applications in microbial mitigation and decay deterrence. [Extracted from the article]

Researchers at Central China Normal University have published a review paper on the synthesis of chiral allenes through asymmetric 1,4-difunctionalization of 1,3-enynes. Chiral allenes are organic molecules with unique physical and chemical properties that are important in modern chemistry. The paper provides an overview of recent advancements in this field, highlighting two distinct strategies: non-radical and radical processes. The research aims to provide valuable insights and ideas for further studies in this area. Funding for the research was provided by the National Natural Science Foundation of China and Central China Normal University. [Extracted from the article]

A report from the Chinese Academy of Medical Sciences in Tianjin, People's Republic of China, discusses the role of autophagy in cancer and the potential use of polymeric nanomaterials to regulate autophagy for cancer therapy. Autophagy is a biological mechanism that plays a role in cell growth, death, and energy metabolism, and is important for removing damaged organelles and proteins. The review paper explores how polymeric nanomaterials can influence the fate of cancer cells by promoting or suppressing the autophagy pathway. The research provides an overview of different types of polymeric nanomaterials and their applications in cancer therapy. [Extracted from the article]

A study conducted by researchers at the College for Chemistry and Chemical Engineering in Changsha, People's Republic of China, has introduced an improved route to Urapidil, an important drug used for the treatment of essential hypertension and hypertensive emergencies. The researchers developed a new synthetic route that starts with the addition reaction of 1-(2-methoxyphenyl)piperazine and oxetane. The overall yield of this route is approximately 45%. The structure of the final product was confirmed through various analytical techniques. This research has been peer-reviewed and published in Chemical Papers. [Extracted from the article]

A report from Al-Rafidain University College in Baghdad, Iraq, discusses the emerging field of environmentally sustainable synthesis of Metal-Organic Frameworks (MOFs) incorporating copper nanoparticles for the treatment of Gram-negative bacterial infections. The paper examines various strategies that prioritize eco-friendly principles and reducing environmental impact. The review aims to provide an overview of the effectiveness, challenges, and potential applications of MOF-based Cu nanoparticles synthesized through environmentally conscious methods in addressing Gram-negative bacterial infections. The research contributes to the evolving paradigm of sustainable antibacterial strategies and offers valuable insights for researchers and practitioners committed to therapeutic efficacy and environmental responsibility. [Extracted from the article]

A recent study conducted in Tamil Nadu, India, has found that Actinobacteria, a type of bacteria, produce bioactive compounds with various beneficial properties, including antioxidative, anti-inflammatory, anticancer, antimicrobial, and antiviral attributes. The study focused on Actinomycetalesbacterium spp. isolated from a hot spring in Rajgir, which was found to produce a brown pigment and various metabolites. One of the metabolites, Diethyl Phthalate (DEP), exhibited in vitro antibacterial activity against Listeria monocytogenes. The research suggests that this isolated bacterium holds promise for antibacterial applications, particularly against L. monocytogenes. [Extracted from the article]

Researchers from Heilongjiang University of Traditional Chinese Medicine have synthesized a novel photothermal nanomaterial called ZnSe-PAM for the treatment of knee osteoarthritis (KOA). The nanomaterial was found to have excellent water solubility, biocompatibility, and stability, making it suitable as a drug carrier. It was loaded with a drug and shown to facilitate drug release by generating heat, reducing the symptoms of KOA. These findings suggest a new direction for drug intervention in KOA and highlight the potential of ZnSe-PAM nanomaterials as novel drug carriers. [Extracted from the article]

Researchers at the University of Shanghai for Science and Technology have developed a sensitive and rapid technique for detecting theophylline, a widely used bronchodilator drug. The researchers fabricated a modified electrode using zinc oxide nanoparticles and multiwalled carbon nanotubes, which showed good sensitivity, selectivity, and stability in detecting theophylline. The technique was successfully applied to determine theophylline in pharmaceutical formulations. This research contributes to the field of nanotechnology and has potential applications in health and medicine. [Extracted from the article]

A recent article in Drug Week discusses the use of holotomography (HT) in advanced bio research. HT is a 3D optical microscopy technique that allows for high-resolution examination inside cells and tissues without the need for staining or preprocessing. It has potential applications in regenerative medicine, personalized medicine, and infertility treatment. The article highlights the advantages and broad applicability of HT, as well as the challenges and future developments in the field. The research was conducted by a team from the Korea Advanced Institute of Science and Technology (KAIST) and was published in 'Nature Reviews Methods Primers'. [Extracted from the article]

A new report from Jining Medical University in China discusses the development of a 3D terbium-based metal-organic framework for luminescent sensing of nitroimidazole antibiotics. The framework, called Tb-MOF, was found to have a substantial quantum yield and selective luminescence quenching for nitroimidazole antibiotics. The researchers concluded that the Tb-MOF could be used as a simple and convenient test paper for detecting metronidazole. This research provides valuable insights into the development of new methods for antibiotic detection. [Extracted from the article]

Researchers at the University of the Punjab in Lahore, Pakistan have conducted a study on the antiepileptic properties of the leaves extract of Terminalia bellirica Roxb. in a chronic PTZ-kindling epilepsy model. The study found that the methanolic extract of the leaves demonstrated reduced seizure frequency, mean seizure score, and cumulative duration, comparable to diazepam. Additionally, significant behavioral improvements were observed in mice treated with the extract. This research suggests that the methanolic extract of Terminalia bellirica leaves shows promise as a novel neuroprotective herbal treatment for epilepsy and its associated behavioral and cognitive impairments. [Extracted from the article]

A recent report from Sun Yat-sen University in Guangzhou, China discusses research on obesity, fitness, and wellness. The study focuses on the use of Magnetic Resonance (MR) images for radiotherapy planning, but notes that functional computed tomography (CT) is still necessary for dose calculation in clinical settings. The researchers propose a novel unsupervised image synthesis framework with registration networks, using deep-learning approaches to synthesize CT images from MR images. The study evaluates the model's performance using head and neck data from 180 patients with nasopharyngeal carcinoma and concludes that the proposed model outperforms other methods in image synthesis quality. The research is considered significant for the study of MR-only radiotherapy planning. [Extracted from the article]

A study conducted at Hebei General Hospital in China aimed to identify the risk factors for cervical lymph node metastasis in patients with medullary thyroid carcinoma (MTC). The researchers conducted a systematic review and meta-analysis of 28 papers and found that tumor size, multifocality, bilaterality, capsular invasion, and extrathyroidal extension were the main risk factors for central lymph node metastasis (CLNM) in MTC patients. Additionally, gender, tumor size, multifocality, bilaterality, capsular invasion, extrathyroidal extension, margin of the tumor, shape of the tumor, preoperative calcitonin level, preoperative carcinoembryonic antigen level, and CLNM were identified as risk factors for lateral cervical lymph node metastasis (LLNM) in MTC patients. These findings can guide individualized treatment plans and improve the prognosis of MTC patients. [Extracted from the article]

According to news reporting out of Guiyang, People's Republic of China, by NewsRx editors, research stated, "This paper considers an optimization problem of switched dynami-cal processes, which is essentially a mixed integer optimization problem. Keywords for this news article include: Guiyang, People's Republic of China, Asia, Obesity, Fitness and Wellness, Guizhou Normal University. Keywords: Guiyang; People's Republic of China; Asia; Obesity Fitness and Wellness EN Guiyang People's Republic of China Asia Obesity Fitness and Wellness 858 858 1 03/27/23 20230331 NES 230331 2023 MAR 31 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators discuss new findings in Obesity, Fitness and Wellness. [Extracted from the article]

Keywords: Singapore; Asia; Obesity Fitness and Wellness; Drugs and Therapies; Health and Medicine; Radiotherapy; Therapy EN Singapore Asia Obesity Fitness and Wellness Drugs and Therapies Health and Medicine Radiotherapy Therapy 791 791 1 03/24/23 20230217 NES 230217 2023 FEB 17 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on Obesity, Fitness and Wellness. Out-of-field doses, which are the doses received by regions outside of the treatment field, are unavoidable regardless of the treatment modalities used during radiotherapy." Other than fetal dose resulting from conventional photon therapy, this paper will also extend the dis-cussion to modern treatment modalities and techniques, namely proton therapy and image-guided radiotherapy, all of which have seen a significant increase in use in current radiotherapy.". [Extracted from the article]

A report from Sungkyunkwan University in Suwon, South Korea discusses the advancements, challenges, and future prospects of kidney-on-chip (KOC) technology in studying antibiotic-induced kidney injury. The review paper identifies key issues and outlines future directions for KOC research, aiming to address challenges such as limited throughput and the need for more accurate physiological replication. The researchers propose exploring sensor integration, high-throughput screening capabilities, and automation to improve the efficiency and predictability of drug-testing methodologies. The research was supported by the National Research Council of Science & Technology (NST), Republic of Korea, and has been peer-reviewed. [Extracted from the article]

A recent report from investigators at Chengdu University of Traditional Chinese Medicine discusses the importance of protein-small molecule interactions in the life activities of organisms. The researchers review the recent advances in methods to detect these interactions, including optical, thermodynamic, and chromatographic principles. The paper also discusses the types of small molecules that these methods are suitable for and the potential for combining different methods in the field of complex small molecule drugs. This research has been peer-reviewed and published in the Chinese Journal of Analytical Chemistry. [Extracted from the article]

A recent study from Lovely Professional University in Punjab, India explores the use of aptamers in nanomedicine. Aptamers are molecular tools that show promise in targeted therapeutics, diagnostics, and drug delivery systems. The study highlights the advantages of aptamers over antibodies, such as selectivity, low immunogenicity, and a simple production process. It also discusses the integration of artificial intelligence, machine learning, and nanotechnology in aptamer development, as well as the challenges and ethical concerns associated with these technologies. The research concludes that aptamers have immense potential in the field of nanomedicine and provides a valuable resource for researchers and practitioners in this area. [Extracted from the article]

A recent study conducted by researchers from Van Lang University in Ho Chi Minh City, Vietnam, explored the interaction between tetradecyltrimethylammonium bromide (TTAB) and promethazine hydrochloride (PMH) mixtures in the presence of various hydrotropes. The researchers examined the micellization characteristics of the mixtures by measuring conductivity and observed that the presence of sodium salicylate (NaS) disrupted micelle development, while sodium benzoate (NaB) and p-amino benzoic acids (4-AmBA) promoted micelle formation. The study also analyzed the thermodynamic parameters and concluded that the interaction forces among the components were electrostatic and hydrophobic in nature. This research provides valuable insights into the behavior of these antiemetic-antivertigo agents and their potential applications in pharmaceuticals. [Extracted from the article]