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Start Over Author "Maria Hauge Pedersen" Journal communications biology
2 results on '"Maria Hauge Pedersen"'

1. OZITX, a pertussis toxin-like protein for occluding inhibitory G protein signalling including Gαz

Author

Alastair C. Keen, Maria Hauge Pedersen, Laura Lemel, Daniel J. Scott, Meritxell Canals, Dene R. Littler, Travis Beddoe, Yuki Ono, Lei Shi, Asuka Inoue, Jonathan A. Javitch, and J. Robert Lane

Subjects
Biology (General), QH301-705.5
Abstract

A recently identified pertussis toxin-like AB5 toxin, OZITX, is found to inhibit Gαi/o and Gαz G proteins. In combination with directed mutations, it is a useful tool for interrogating Gαi/o/z G protein subunits individually.

Published
2022
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2. OZITX, a pertussis toxin-like protein for occluding inhibitory G protein signalling including Gα

Author

Alastair C, Keen, Maria Hauge, Pedersen, Laura, Lemel, Daniel J, Scott, Meritxell, Canals, Dene R, Littler, Travis, Beddoe, Yuki, Ono, Lei, Shi, Asuka, Inoue, Jonathan A, Javitch, and J Robert, Lane

Subjects
Pertussis Toxin, GTP-Binding Protein alpha Subunits, Gi-Go, Heterotrimeric GTP-Binding Proteins, Receptors, G-Protein-Coupled, Signal Transduction
Abstract

Heterotrimeric G proteins are the main signalling effectors for G protein-coupled receptors. Understanding the distinct functions of different G proteins is key to understanding how their signalling modulates physiological responses. Pertussis toxin, a bacterial AB

Published
2021

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