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Your search keyword '"Carlo Augusto Mallio"' showing total 2 results
Start Over Author "Carlo Augusto Mallio" Journal clinical cancer investigation journal
2 results on '"Carlo Augusto Mallio"'

1. Subcutaneous adipose tissue as a biomarker of pancreatic cancer: A pilot study in male patients

Author

Vincenzo Cirimele, Carlo Augusto Mallio, Federico Greco, Rosario Francesco Grasso, and Bruno Beomonte Zobel

Subjects
Pathology, medicine.medical_specialty, business.industry, Adipose tissue, Retrospective cohort study, General Medicine, medicine.disease, Adrenomedullin, 03 medical and health sciences, 0302 clinical medicine, Male patient, 030220 oncology & carcinogenesis, Pancreatic cancer, Quantitative assessment, medicine, Biomarker (medicine), Subcutaneous adipose tissue, business, 030215 immunology
Abstract

Purpose: The purpose of this study was to evaluate the relationship between subcutaneous adipose tissue (SAT) and pancreatic cancer (PC) in male patients. Methods: In this retrospective study, two groups were included. Quantitative assessment of adipose tissue was performed by measuring total adipose tissue (TAT) area, visceral adipose tissue (VAT) area, and the SAT area in both the groups. Then, VAT/SAT ratio was calculated. Results: Statistically significant differences between the two groups were found in the SAT area (P

Published
2019

2. Increased visceral adipose tissue in male patients with clear cell renal cell carcinoma

Author

Bruno Beomonte Zobel, Rosario Francesco Grasso, Carlo Augusto Mallio, Vincenzo Cirimele, and Federico Greco

Subjects
0301 basic medicine, medicine.medical_specialty, business.industry, Adipose tissue, Adipokine, Retrospective cohort study, General Medicine, medicine.disease, medicine.disease_cause, Obesity, 03 medical and health sciences, chemistry.chemical_compound, Clear cell renal cell carcinoma, Adiposopathy, 030104 developmental biology, 0302 clinical medicine, Endocrinology, chemistry, 030220 oncology & carcinogenesis, Internal medicine, Adipocyte, medicine, business, Carcinogenesis
Abstract

Background: Excessive accumulation of adipose tissue, mainly visceral, can determine adipocyte- and adipose tissue-related disorder. Visceral adipocytes secrete mediators associated with carcinogenesis. Several studies have shown a correlation between blood levels of these mediators and clear cell renal cell carcinoma (ccRCC). Indeed, specific biomarkers, including adipokines, have been considered as a possible link between obesity and RCC. Objective: The objective of the study is to test the hypothesis that there is an increase of visceral adipose tissue (VAT) in male patients with ccRCC. Methods: In this retrospective study, two groups were included: A group of patients with ccRCC and a control group without a history of malignancies. Total adipose tissue (TAT) area, VAT area, and subcutaneous adipose tissue (SAT) area were measured in both groups. VAT/SAT ratio was subsequently calculated. Results: Statistically significant differences between the two groups were found in VAT area (P = 0.01) and VAT/SAT ratio (P

Published
2018

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