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Start Over Author "Zhu, Yinghui" Journal clinical & translational medicine
1 results on '"Zhu, Yinghui"'

1. Phosphoproteomics profiling reveals a kinase network conferring acute myeloid leukaemia intrinsic chemoresistance and indicates HMGA1 phosphorylation as a potential influencer.

Author

Zhu, Yinghui, He, Xin, Li, Shu, Gan, Yichao, Li, Zheng, Wang, Hanying, Dong, Haojie, Zhang, Lei, Xue, Sheng‐Li, Xu, Yang, and Li, Ling

Subjects
*ACUTE myeloid leukemia, *DRUG resistance in cancer cells, *PROTEIN kinase CK2
Abstract

(J) ChIP-qPCR assay in 293T cells that ectopically overexpress Flag-tagged HMGA1-WT or HMGA1-S3A, and with siSP1 in these Flag-HMGA1 expressing cells. (B) Western blotting for pan-phospho-serine levels in 293T cells transduced with MOCK, Flag-tagged HMGA1-WT, HMGA1-S99A, HMGA1-S102A, HMGA1-S103A or HMGA1-S3A. ChIP analysis using anti-flag antibodies or control normal mouse IgG was performed in four groups: HMGA1-WT/siCtrl, HMGA1-WT/siSP1, HMGA1-S3A/siCtrl and HMGA1-S3A/siSP1. [Extracted from the article]

Published
2022
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