Author: "O'Connor, Christopher" / Journal: circulation: heart failure - Searchworks@Jio Institute Digital Library Search Results

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1. Evolution of NT-proBNP During Prerandomization Screening in VICTORIA: Implications for Clinical Outcomes and Efficacy of Vericiguat

Author: Armstrong, Paul W., Zheng, Yinggan, Lund, Lars H., Butler, Javed, Troughton, Richard W., Emdin, Michele, Lam, Carolyn S.P., Ponikowski, Piotr, Blaustein, Robert O., O’Connor, Christopher M., Roessig, Lothar, Voors, Adriaan A., Ezekowitz, Justin A., and Westerhout, Cynthia M.
Published: 2023
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2. Background Medical Therapy and Clinical Outcomes From the VICTORIA Trial

Author: Ezekowitz, Justin A., McMullan, Ciaran J., Westerhout, Cynthia M., Piña, Ileana L., Lopez-Sendon, Jose, Anstrom, Kevin J., Hernandez, Adrian F., Lam, Carolyn S.P., O’Connor, Christopher M., Pieske, Burkert, Ponikowski, Piotr, Roessig, Lothar, Voors, Adriaan A., Koglin, Joerg, Armstrong, Paul W., and Butler, Javed
Published: 2023
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3. A Composite Score Summarizing Use and Dosing of Evidence-Based Medical Therapies in Heart Failure: A Nationwide Cohort Study

Author: Johansen, Niklas Dyrby, Vaduganathan, Muthiah, Zahir, Deewa, Fiuzat, Mona, DeFilippis, Ersilia M., Januzzi, James L., Butler, Javed, O’Connor, Christopher M., Abraham, William T., Psotka, Mitchell A., McMurray, John J.V., Dewan, Pooja, Claggett, Brian L., Solomon, Scott D., Modin, Daniel, Butt, Jawad H., Jensen, Jens Ulrik Stæhr, Schou, Morten, Torp-Pedersen, Christian, Køber, Lars, Gislason, Gunnar H., and Biering-Sørensen, Tor
Published: 2023
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4. Polygenic Score for β-Blocker Survival Benefit in European Ancestry Patients With Reduced Ejection Fraction Heart Failure

Author: Lanfear, David E., Luzum, Jasmine A., She, Ruicong, Gui, Hongsheng, Donahue, Mark P., O’Connor, Christopher M., Adams, Kirkwood F., Sanders-van Wijk, Sandra, Zeld, Nicole, Maeder, Micha T., Sabbah, Hani N., Kraus, William E., Brunner-LaRocca, Hans-Peter, Li, Jia, and Williams, L. Keoki
Published: 2020
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5. Representation of Women Authors in International Heart Failure Guidelines and Contemporary Clinical Trials

Author: Reza, Nosheen, Tahhan, Ayman Samman, Mahmud, Nadim, DeFilippis, Ersilia M., Alrohaibani, Alaaeddin, Vaduganathan, Muthiah, Greene, Stephen J., Ho, Annie Hang, Fonarow, Gregg C., Butler, Javed, O’Connor, Christopher, Fiuzat, Mona, Vardeny, Orly, Piña, Ileana L., Lindenfeld, JoAnn, and Jessup, Mariell
Published: 2020
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6. Sex Differences in Quality of Life and Clinical Outcomes in Patients With Advanced Heart Failure: Insights From the PAL-HF Trial

Author: Truby, Lauren K., O’Connor, Christopher, Fiuzat, Mona, Stebbins, Amanda, Coles, Adrian, Patel, Chetan B., Granger, Bradi, Pagidipati, Neha, Agarwal, Richa, Rymer, Jennifer, Lowenstern, Angela, Douglas, Pamela S., Tulsky, James, Rogers, Joseph G., and Mentz, Robert J.
Published: 2020
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7. Rationale and Design of the VITALITY-HFpEF Trial

Author: Butler, Javed, Lam, Carolyn S.P., Anstrom, Kevin J., Ezekowitz, Justin, Hernandez, Adrian F., O’Connor, Christopher M., Pieske, Burkert, Ponikowski, Piotr, Shah, Sanjiv J., Solomon, Scott D., Voors, Adriaan A., Wu, Yi, Carvalho, Francine, Bamber, Luke, Blaustein, Robert O., Roessig, Lothar, and Armstrong, Paul W.
Published: 2019
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8. Novel Mitochondria-Targeting Peptide in Heart Failure Treatment: A Randomized, Placebo-Controlled Trial of Elamipretide

Author: Daubert, Melissa A., Yow, Eric, Dunn, Gary, Marchev, Sotir, Barnhart, Huiman, Douglas, Pamela S., O’Connor, Christopher, Goldstein, Sidney, Udelson, James E., and Sabbah, Hani N.
Published: 2017
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9. Cardiogenic Shock From Heart Failure Versus Acute Myocardial Infarction: Clinical Characteristics, Hospital Course, and 1-Year Outcomes

Author: Sinha, Shashank S., primary, Rosner, Carolyn M., additional, Tehrani, Behnam N., additional, Maini, Aneel, additional, Truesdell, Alexander G., additional, Lee, Seiyon Ben, additional, Bagchi, Pramita, additional, Cameron, James, additional, Damluji, Abdulla A., additional, Desai, Mehul, additional, Desai, Shashank S., additional, Epps, Kelly C., additional, deFilippi, Christopher, additional, Flanagan, M. Casey, additional, Genovese, Leonard, additional, Moukhachen, Hala, additional, Park, James J., additional, Psotka, Mitchell A., additional, Raja, Anika, additional, Shah, Palak, additional, Sherwood, Matthew W., additional, Singh, Ramesh, additional, Tang, Daniel, additional, Young, Karl D., additional, Welch, Timothy, additional, O’Connor, Christopher M., additional, and Batchelor, Wayne B., additional
Published: 2022
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10. Effects of Coping Skills Training on Quality of Life, Disease Biomarkers, and Clinical Outcomes in Patients With Heart Failure: A Randomized Clinical Trial

Author: Sherwood, Andrew, Blumenthal, James A., Koch, Gary G., Hoffman, Benson M., Watkins, Lana L., Smith, Patrick J., O’Connor, Christopher M., Adams, Kirkwood F., Jr, Rogers, Joseph G., Sueta, Carla, Chang, Patricia P., Johnson, Kristy S., Schwartz, Jeanne, and Hinderliter, Alan L.
Published: 2017
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11. Associations of Body Mass Index With Laboratory and Biomarkers in Patients With Acute Heart Failure

Author: Streng, Koen W., ter Maaten, Jozine M., Cleland, John G., O’Connor, Christopher M., Davison, Beth A., Metra, Marco, Givertz, Michael M., Teerlink, John R., Ponikowski, Piotr, Bloomfield, Daniel M., Dittrich, Howard C., Hillege, Hans L., van Veldhuisen, Dirk J., Voors, Adriaan A., and van der Meer, Peter
Published: 2017
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12. Participation in a Heart Failure Clinical Trial

Author: Ezekowitz, Justin, primary, Mentz, Robert J., additional, Westerhout, Cynthia M., additional, Sweitzer, Nancy K., additional, Givertz, Michael M., additional, Piña, Ileana L., additional, O’Connor, Christopher M., additional, Greene, Stephen J., additional, McMullan, Ciaran, additional, Roessig, Lothar, additional, Hernandez, Adrian F., additional, and Armstrong, Paul W., additional
Published: 2021
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13. Prognostic Role of Prior Heart Failure Hospitalization Among Patients Hospitalized for Worsening Chronic Heart Failure

Author: Blumer, Vanessa, primary, Mentz, Robert J., additional, Sun, Jie-Lena, additional, Butler, Javed, additional, Metra, Marco, additional, Voors, Adriaan A., additional, Hernandez, Adrian F., additional, O’Connor, Christopher M., additional, and Greene, Stephen J., additional
Published: 2021
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14. Renal Function Trajectories and Clinical Outcomes in Acute Heart Failure

Author: Valente, Mattia A. E., Voors, Adriaan A., Damman, Kevin, Veldhuisen, Dirk J. Van, Massie, Barrie M., O'Connor, Christopher M., Metra, Marco, Ponikowski, Piotr, Teerlink, John R., Cotter, Gad, Davison, Beth, Cleland, John G. F., Givertz, Michael M., Bloomfield, Daniel M., Fiuzat, Mona, Dittrich, Howard C., Hillege, Hans L., Life Course Epidemiology (LCE), Cardiovascular Centre (CVC), Groningen Kidney Center (GKC), and Methods in Medicines evaluation & Outcomes research (M2O)
Subjects: Male, Acute decompensated heart failure, IMPACT, heart failure, Comorbidity, Kidney, Rolofylline, Blood Urea Nitrogen, Kidney Failure, chemistry.chemical_compound, Models, 80 and over, IN-HOSPITAL MORTALITY, Chronic, Blood urea nitrogen, Randomized Controlled Trials as Topic, Aged, 80 and over, Ejection fraction, Middle Aged, Survival Rate, Treatment Outcome, Creatinine, Cardiology, Biological Markers, Female, TRIAL, Cardiology and Cardiovascular Medicine, hospitalization, medicine.medical_specialty, Renal function, Cardiorenal syndrome, PRESSURE, Models, Biological, Predictive Value of Tests, Internal medicine, medicine, Humans, cardiorenal syndrome, mortality, Aged, Follow-Up Studies, Heart Failure, Kidney Failure, Chronic, Multivariate Analysis, Purinergic P1 Receptor Antagonists, Xanthines, Intensive care medicine, ANTAGONIST, MEDICARE BENEFICIARIES, business.industry, Biological, medicine.disease, DYSFUNCTION, MODEL, ROLOFYLLINE, chemistry, PROTECT, Heart failure, business, Biomarkers
Abstract: Background— Prior studies have demonstrated adverse risk associated with baseline and worsening renal function in acute heart failure, but none has modeled the trajectories of change in renal function and their impact on outcomes. Methods and Results— We used linear mixed models of serial measurements of blood urea nitrogen and creatinine to describe trajectories of renal function in 1962 patients with acute heart failure and renal dysfunction enrolled in the Placebo-Controlled Randomized Study of the Selective A 1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized with Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function study. We assessed risk of 180-day mortality and 60-day cardiovascular or renal readmission and used Cox regression to determine association between renal trajectories and outcomes. Compared with patients alive at 180 days, patients who died were older, had lower blood pressure and ejection fraction, and higher creatinine levels at baseline. On average for the entire cohort, creatinine rose from days 1 to 3 and increased further after discharge, with the trajectory dependent on the day of discharge. Blood urea nitrogen, creatinine, and the rate of change in creatinine from baseline were the strongest independent predictors of 180-day mortality and 60-day readmission, whereas the rate of change of blood urea nitrogen from baseline was not predictive of outcomes. Baseline blood urea nitrogen >35 mg/dL and increase in creatinine >0.1 mg/dL per day increased the risk of mortality, whereas stable or decreasing creatinine was associated with reduced risk. Conclusions— Patients with acute heart failure and renal dysfunction demonstrate variable rise and fall in renal indices during and immediately after hospitalization. Risk of morbidity and mortality can be predicted based on baseline renal function and creatinine trajectory during the first 7 days. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifiers: NCT00328692 and NCT00354458.
Published: 2014

15. Prognostic Significance of Creatinine Increases During an Acute Heart Failure Admission in Patients With and Without Residual Congestion

Author: Metra, Marco, primary, Cotter, Gad, additional, Senger, Stefanie, additional, Edwards, Christopher, additional, Cleland, John G., additional, Ponikowski, Piotr, additional, Cursack, Guillermo C., additional, Milo, Olga, additional, Teerlink, John R., additional, Givertz, Michael M., additional, O’Connor, Christopher M., additional, Dittrich, Howard C., additional, Bloomfield, Daniel M., additional, Voors, Adriaan A., additional, and Davison, Beth A., additional
Published: 2018
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16. Reassessing Phase II Heart Failure Clinical Trials

Author: Butler, Javed, primary, Hamo, Carine E., additional, Udelson, James E., additional, O’Connor, Christopher, additional, Sabbah, Hani N., additional, Metra, Marco, additional, Shah, Sanjiv J., additional, Kitzman, Dalane W., additional, Teerlink, John R., additional, Bernstein, Harold S., additional, Brooks, Gabriel, additional, Depre, Christophe, additional, DeSouza, Mary M., additional, Dinh, Wilfried, additional, Donovan, Mark, additional, Frische-Danielson, Regina, additional, Frost, Robert J., additional, Garza, Dahlia, additional, Gohring, Udo-Michael, additional, Hellawell, Jennifer, additional, Hsia, Judith, additional, Ishihara, Shiro, additional, Kay-Mugford, Patricia, additional, Koglin, Joerg, additional, Kozinn, Marc, additional, Larson, Christopher J., additional, Mayo, Martha, additional, Gan, Li-Ming, additional, Mugnier, Pierrre, additional, Mushonga, Sekayi, additional, Roessig, Lothar, additional, Russo, Cesare, additional, Salsali, Afshin, additional, Satler, Carol, additional, Shi, Victor, additional, Ticho, Barry, additional, van der Laan, Michael, additional, Yancy, Clyde, additional, Stockbridge, Norman, additional, and Gheorghiade, Mihai, additional
Published: 2017
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17. Influence of Clinical Trial Site Enrollment on Patient Characteristics, Protocol Completion, and End Points

Author: Greene, Stephen J., primary, Hernandez, Adrian F., additional, Sun, Jie-Lena, additional, Metra, Marco, additional, Butler, Javed, additional, Ambrosy, Andrew P., additional, Ezekowitz, Justin A., additional, Starling, Randall C., additional, Teerlink, John R., additional, Schulte, Phillip J., additional, Voors, Adriaan A., additional, Armstrong, Paul W., additional, O’Connor, Christopher M., additional, and Mentz, Robert J., additional
Published: 2016
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18. Hypochloremia, Diuretic Resistance, and Outcome in Patients With Acute Heart Failure

Author: ter Maaten, Jozine M., primary, Damman, Kevin, additional, Hanberg, Jennifer S., additional, Givertz, Michael M., additional, Metra, Marco, additional, O’Connor, Christopher M., additional, Teerlink, John R., additional, Ponikowski, Piotr, additional, Cotter, Gad, additional, Davison, Beth, additional, Cleland, John G., additional, Bloomfield, Daniel M., additional, Hillege, Hans L., additional, van Veldhuisen, Dirk J., additional, Voors, Adriaan A., additional, and Testani, Jeffrey M., additional
Published: 2016
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19. Implications of Using Different Definitions on Outcomes in Worsening Heart Failure

Author: Kelly, Jacob P., primary, Cooper, Lauren B., additional, Gallup, Dianne, additional, Anstrom, Kevin J., additional, Chen, Horng H., additional, Redfield, Margaret M., additional, O’Connor, Christopher M., additional, Mentz, Robert J., additional, Hernanadez, Adrian F., additional, and Felker, G. Michael, additional
Published: 2016
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20. Baseline Hemodynamics and Response to Contrast Media During Diagnostic Cardiac Catheterization Predict Adverse Events in Heart Failure Patients

Author: Denardo, Scott J., primary, Vock, David M., additional, Schmalfuss, Carsten M., additional, Young, Gregory D., additional, Tcheng, James E., additional, and O’Connor, Christopher M., additional
Published: 2016
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21. Combining Diuretic Response and Hemoconcentration to Predict Rehospitalization After Admission for Acute Heart Failure

Author: ter Maaten, Jozine M., primary, Valente, Mattia A.E., additional, Damman, Kevin, additional, Cleland, John G., additional, Givertz, Michael M., additional, Metra, Marco, additional, O’Connor, Christopher M., additional, Teerlink, John R., additional, Ponikowski, Piotr, additional, Bloomfield, Daniel M., additional, Cotter, Gadi, additional, Davison, Beth, additional, Subacius, Haris, additional, van Veldhuisen, Dirk J., additional, van der Meer, Peter, additional, Hillege, Hans L., additional, Gheorghiade, Mihai, additional, and Voors, Adriaan A., additional
Published: 2016
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22. Psychosocial Factors, Exercise Adherence, and Outcomes in Heart Failure Patients

Author: Cooper, Lauren B., primary, Mentz, Robert J., additional, Sun, Jie-Lena, additional, Schulte, Phillip J., additional, Fleg, Jerome L., additional, Cooper, Lawton S., additional, Piña, Ileana L., additional, Leifer, Eric S., additional, Kraus, William E., additional, Whellan, David J., additional, Keteyian, Steven J., additional, and O’Connor, Christopher M., additional
Published: 2015
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23. Tolvaptan in Patients Hospitalized With Acute Heart Failure

Author: Felker, G. Michael, primary, Mentz, Robert J., additional, Adams, Kirkwood F., additional, Cole, Robert T., additional, Egnaczyk, Gregory F., additional, Patel, Chetan B., additional, Fiuzat, Mona, additional, Gregory, Douglas, additional, Wedge, Patricia, additional, O’Connor, Christopher M., additional, Udelson, James E., additional, and Konstam, Marvin A., additional
Published: 2015
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24. Evaluation of the Incremental Prognostic Utility of Increasingly Complex Testing in Chronic Heart Failure

Author: Ahmad, Tariq, primary, O’Brien, Emily C., additional, Schulte, Phillip J., additional, Stevens, Susanna R., additional, Fiuzat, Mona, additional, Kitzman, Dalane W., additional, Adams, Kirkwood F., additional, Kraus, William E., additional, Piña, Ileana L., additional, Donahue, Mark P., additional, Zannad, Faiez, additional, Whellan, David J., additional, O’Connor, Christopher M., additional, and Felker, G. Michael, additional
Published: 2015
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25. Prognostic Significance of Depression in Blacks With Heart Failure

Author: Mentz, Robert J., primary, Babyak, Michael A., additional, Bittner, Vera, additional, Fleg, Jerome L., additional, Keteyian, Steven J., additional, Swank, Ann M., additional, Piña, Ileana L., additional, Kraus, William E., additional, Whellan, David J., additional, O’Connor, Christopher M., additional, and Blumenthal, James A., additional
Published: 2015
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26. Hypotension During Hospitalization for Acute Heart Failure Is Independently Associated With 30-Day Mortality

Author: Patel, Priyesh A., primary, Heizer, Gretchen, additional, O’Connor, Christopher M., additional, Schulte, Phillip J., additional, Dickstein, Kenneth, additional, Ezekowitz, Justin A., additional, Armstrong, Paul W., additional, Hasselblad, Vic, additional, Mills, Roger M., additional, McMurray, John J.V., additional, Starling, Randall C., additional, Tang, W.H. Wilson, additional, Califf, Robert M., additional, and Hernandez, Adrian F., additional
Published: 2014
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27. Predictors of Postdischarge Outcomes From Information Acquired Shortly After Admission for Acute Heart Failure

Author: Cleland, John G., primary, Chiswell, Karen, additional, Teerlink, John R., additional, Stevens, Susanna, additional, Fiuzat, Mona, additional, Givertz, Michael M., additional, Davison, Beth A., additional, Mansoor, George A., additional, Ponikowski, Piotr, additional, Voors, Adriaan A., additional, Cotter, Gad, additional, Metra, Marco, additional, Massie, Barry M., additional, and O’Connor, Christopher M., additional
Published: 2014
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28. Clinical Effectiveness of Cardiac Resynchronization and Implantable Cardioverter-Defibrillator Therapy in Men and Women With Heart Failure

Author: Wilcox, Jane E., primary, Fonarow, Gregg C., additional, Zhang, Yan, additional, Albert, Nancy M., additional, Curtis, Anne B., additional, Gheorghiade, Mihai, additional, Heywood, J. Thomas, additional, Mehra, Mandeep R., additional, O’Connor, Christopher M., additional, Reynolds, Dwight, additional, Walsh, Mary Norine, additional, and Yancy, Clyde W., additional
Published: 2014
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29. Renal Function Trajectories and Clinical Outcomes in Acute Heart Failure

Author: Givertz, Michael M., primary, Postmus, Douwe, additional, Hillege, Hans L., additional, Mansoor, George A., additional, Massie, Barry M., additional, Davison, Beth A., additional, Ponikowski, Piotr, additional, Metra, Marco, additional, Teerlink, John R., additional, Cleland, John G.F., additional, Dittrich, Howard C., additional, O’Connor, Christopher M., additional, Cotter, Gad, additional, and Voors, Adriaan A., additional
Published: 2014
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30. Soluble ST2 in Ambulatory Patients With Heart Failure

Author: Felker, G. Michael, primary, Fiuzat, Mona, additional, Thompson, Vivian, additional, Shaw, Linda K., additional, Neely, Megan L., additional, Adams, Kirkwood F., additional, Whellan, David J., additional, Donahue, Mark P., additional, Ahmad, Tariq, additional, Kitzman, Dalane W., additional, Piña, Ileana L., additional, Zannad, Faiez, additional, Kraus, William E., additional, and O’Connor, Christopher M., additional
Published: 2013
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31. Do Countries or Hospitals With Longer Hospital Stays for Acute Heart Failure Have Lower Readmission Rates?

Author: Eapen, Zubin J., primary, Reed, Shelby D., additional, Li, Yanhong, additional, Kociol, Robb D., additional, Armstrong, Paul W., additional, Starling, Randall C., additional, McMurray, John J., additional, Massie, Barry M., additional, Swedberg, Karl, additional, Ezekowitz, Justin A., additional, Fonarow, Gregg C., additional, Teerlink, John R., additional, Metra, Marco, additional, Whellan, David J., additional, O’Connor, Christopher M., additional, Califf, Robert M., additional, and Hernandez, Adrian F., additional
Published: 2013
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32. Is There a Rationale for Antiplatelet Therapy in Acute Heart Failure?

Author: Mentz, Robert J., primary, Lazzarini, Valentina, additional, Fiuzat, Mona, additional, Metra, Marco, additional, O’Connor, Christopher M., additional, and Felker, G. Michael, additional
Published: 2013
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33. Markers of Decongestion, Dyspnea Relief, and Clinical Outcomes Among Patients Hospitalized With Acute Heart Failure

Author: Kociol, Robb D., primary, McNulty, Steven E., additional, Hernandez, Adrian F., additional, Lee, Kerry L., additional, Redfield, Margaret M., additional, Tracy, Russell P., additional, Braunwald, Eugene, additional, O’Connor, Christopher M., additional, and Felker, G. Michael, additional
Published: 2013
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34. Acute Heart Failure

Author: Ezekowitz, Justin A., primary, Hu, Jia, additional, Delgado, Diego, additional, Hernandez, Adrian F., additional, Kaul, Padma, additional, Leader, Rolland, additional, Proulx, Guy, additional, Virani, Sean, additional, White, Michel, additional, Zieroth, Shelley, additional, O’Connor, Christopher, additional, Westerhout, Cynthia M., additional, and Armstrong, Paul W., additional
Published: 2012
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35. Factors Related to Morbidity and Mortality in Patients With Chronic Heart Failure With Systolic Dysfunction

Author: O'Connor, Christopher M., primary, Whellan, David J., additional, Wojdyla, Daniel, additional, Leifer, Eric, additional, Clare, Robert M., additional, Ellis, Stephen J., additional, Fine, Lawrence J., additional, Fleg, Jerome L., additional, Zannad, Faiez, additional, Keteyian, Steven J., additional, Kitzman, Dalane W., additional, Kraus, William E., additional, Rendall, David, additional, Piña, Ileana L., additional, Cooper, Lawton S., additional, Fiuzat, Mona, additional, and Lee, Kerry L., additional
Published: 2012
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36. Galectin-3 in Ambulatory Patients With Heart Failure

Author: Felker, G. Michael, primary, Fiuzat, Mona, additional, Shaw, Linda K., additional, Clare, Robert, additional, Whellan, David J., additional, Bettari, Luca, additional, Shirolkar, Shailesh C., additional, Donahue, Mark, additional, Kitzman, Dalane W., additional, Zannad, Faiez, additional, Piña, Ileana L., additional, and O'Connor, Christopher M., additional
Published: 2012
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37. Impact of Serial Troponin Release on Outcomes in Patients With Acute Heart Failure

Author: O'Connor, Christopher M., primary, Fiuzat, Mona, additional, Lombardi, Carlo, additional, Fujita, Kenji, additional, Jia, Gang, additional, Davison, Beth A., additional, Cleland, John, additional, Bloomfield, Daniel, additional, Dittrich, Howard C., additional, DeLucca, Paul, additional, Givertz, Michael M., additional, Mansoor, George, additional, Ponikowski, Piotr, additional, Teerlink, John R., additional, Voors, Adriaan A., additional, Massie, Barry M., additional, Cotter, Gad, additional, and Metra, Marco, additional
Published: 2011
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38. Admission, Discharge, or Change in B-Type Natriuretic Peptide and Long-Term Outcomes

Author: Kociol, Robb D., primary, Horton, John R., additional, Fonarow, Gregg C., additional, Reyes, Eric M., additional, Shaw, Linda K., additional, O'Connor, Christopher M., additional, Felker, G. Michael, additional, and Hernandez, Adrian F., additional
Published: 2011
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39. Thromboembolism and Antithrombotic Therapy in Patients With Heart Failure in Sinus Rhythm

Author: Bettari, Luca, primary, Fiuzat, Mona, additional, Becker, Richard, additional, Felker, G. Michael, additional, Metra, Marco, additional, and O'Connor, Christopher M., additional
Published: 2011
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40. Comparison of Medical Therapy Dosing in Outpatients Cared for in Cardiology Practices With Heart Failure and Reduced Ejection Fraction With and Without Device Therapy

Author: Heywood, J. Thomas, primary, Fonarow, Gregg C., additional, Yancy, Clyde W., additional, Albert, Nancy M., additional, Curtis, Anne B., additional, Gheorghiade, Mihai, additional, Inge, Patches Johnson, additional, McBride, Mark L., additional, Mehra, Mandeep R., additional, O'Connor, Christopher M., additional, Reynolds, Dwight, additional, and Walsh, Mary Norine, additional
Published: 2010
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41. Clinical Trials of Pharmacological Therapies in Acute Heart Failure Syndromes

Author: Felker, G. Michael, primary, Pang, Peter S., additional, Adams, Kirkwood F., additional, Cleland, John G.F., additional, Cotter, Gad, additional, Dickstein, Kenneth, additional, Filippatos, Gerasimos S., additional, Fonarow, Gregg C., additional, Greenberg, Barry H., additional, Hernandez, Adrian F., additional, Khan, Sadiya, additional, Komajda, Michel, additional, Konstam, Marvin A., additional, Liu, Peter P., additional, Maggioni, Aldo P., additional, Massie, Barry M., additional, McMurray, John J., additional, Mehra, Mandeep, additional, Metra, Marco, additional, O'Connell, John, additional, O'Connor, Christopher M., additional, Pina, Ileana L., additional, Ponikowski, Piotr, additional, Sabbah, Hani N., additional, Teerlink, John R., additional, Udelson, James E., additional, Yancy, Clyde W., additional, Zannad, Faiez, additional, and Gheorghiade, Mihai, additional
Published: 2010
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42. Clinical Effectiveness of Implantable Cardioverter-Defibrillators Among Medicare Beneficiaries With Heart Failure

Author: Hernandez, Adrian F., primary, Fonarow, Gregg C., additional, Hammill, Bradley G., additional, Al-Khatib, Sana M., additional, Yancy, Clyde W., additional, O'Connor, Christopher M., additional, Schulman, Kevin A., additional, Peterson, Eric D., additional, and Curtis, Lesley H., additional
Published: 2010
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43. Loop Diuretics in Acute Decompensated Heart Failure

Author: Felker, G. Michael, primary, O'Connor, Christopher M., additional, and Braunwald, Eugene, additional
Published: 2009
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44. Heart Failure Care in the Outpatient Cardiology Practice Setting

Author: Fonarow, Gregg C., primary, Yancy, Clyde W., additional, Albert, Nancy M., additional, Curtis, Anne B., additional, Stough, Wendy Gattis, additional, Gheorghiade, Mihai, additional, Heywood, J. Thomas, additional, McBride, Mark L., additional, Mehra, Mandeep R., additional, O'Connor, Christopher M., additional, Reynolds, Dwight, additional, and Walsh, Mary Norine, additional
Published: 2008
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45. Admission or Changes in Renal Function During Hospitalization for Worsening Heart Failure Predict Postdischarge Survival

Author: Klein, Liviu, primary, Massie, Barry M., additional, Leimberger, Jeffrey D., additional, O’Connor, Christopher M., additional, Piña, Ileana L., additional, Adams, Kirkwood F., additional, Califf, Robert M., additional, and Gheorghiade, Mihai, additional
Published: 2008
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46. Day of Admission and Clinical Outcomes for Patients Hospitalized for Heart Failure

Author: Fonarow, Gregg C., primary, Abraham, William T., additional, Albert, Nancy M., additional, Gattis Stough, Wendy, additional, Gheorghiade, Mihai, additional, Greenberg, Barry H., additional, O’Connor, Christopher M., additional, Nunez, Eduardo, additional, Yancy, Clyde W., additional, and Young, James B., additional
Published: 2008
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47. Tolvaptan in Patients Hospitalized With Acute Heart Failure.

Author: Michael Felker, G., Mentz, Robert J., Adams, Kirkwood F., Cole, Robert T., Egnaczyk, Gregory F., Patel, Chetan B., Fiuzat, Mona, Gregory, Douglas, Wedge, Patricia, O'Connor, Christopher M., Udelson, James E., and Konstam, Marvin A.
Published: 2015
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48. Vericiguat and Health-Related Quality of Life in Patients With Heart Failure With Reduced Ejection Fraction: Insights From the VICTORIA Trial.

Author: Butler, Javed, Stebbins, Amanda, Melenovský, Vojtěch, Sweitzer, Nancy K., Cowie, Martin R., Stehlik, Josef, Khan, Muhammad Shahzeb, Blaustein, Robert O., Ezekowitz, Justin A., Hernandez, Adrian F., Lam, Carolyn S.P., Nkulikiyinka, Richard, O'Connor, Christopher M., Pieske, Burkert M., Ponikowski, Piotr, Spertus, John A., Voors, Adriaan A., Anstrom, Kevin J., and Armstrong, Paul W.
Abstract: Background: We examined the effects of vericiguat compared with placebo in patients with heart failure with reduced ejection fraction enrolled in VICTORIA (Vericiguat Global Study in Patients With Heart Failure With Reduced Ejection Fraction) on health status outcomes measured by the Kansas City Cardiomyopathy Questionnaire (KCCQ) and evaluated whether clinical outcomes varied by baseline KCCQ score. Methods: KCCQ was completed at baseline and 4, 16, and 32 weeks. We assessed treatment effect on KCCQ using a mixed-effects model adjusting for baseline KCCQ and stratification variables. Cox proportional-hazards modeling was performed to evaluate the effect of vericiguat on clinical outcomes by tertiles of baseline KCCQ clinical summary score (CSS), total symptom score (TSS), and overall summary score (OSS). Results: Of 5050 patients, 4664, 4741, and 4470 had KCCQ CSS (median [25th to 75th], 65.6 [45.8–81.8]), TSS (68.8 [47.9–85.4]), and OSS (59.9 [42.0–77.1]) at baseline; 94%, 88%, and 82% had data at 4, 16, and 32 weeks. At 16 weeks, CSS improved by a median of 6.3 in both arms; no significant differences in improvement were seen for TSS and OSS between the 2 groups (P =0.69, 0.97, and 0.13 for CSS, TSS, and OSS). Trends were similar at 4 and 32 weeks. Vericiguat versus placebo reduced cardiovascular death or heart failure hospitalization risk similarly across tertiles of baseline KCCQ CSS, TSS, and OSS (interaction P =0.13, 0.21, and 0.65). Conclusions: Vericiguat did not significantly improve KCCQ scores compared with placebo. Vericiguat reduced the risk of cardiovascular death or heart failure hospitalization across the range of baseline health status. Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT02861534. [ABSTRACT FROM AUTHOR]
Published: 2022
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49. Health Status and Depression Remission in Patients With Chronic Heart Failure.

Author: Xiong, Glen L., Fiuzat, Mona, Kuchibhatla, Maragatha, Krishnan, Ranga, O'Connor, Christopher M., and Wei Jiang
Subjects: MENTAL depression, HEALTH of patients, HEART failure, SOCIAL skills, HEART diseases
Abstract: The article discusses the occurrence of depression among patients with chronic heart failure. It states that depression is commonly associated with heart failure and it is highly associated with reduced health state of patients. According to the authors, patients with depressive symptoms remitted showed promise in social function, life quality as well as physical function.
Published: 2012
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50. Thromboembolism and Antithrombotic Therapyin Patients With Heart Failure in Sinus Rhythm.

Author: Bettari, Luca, Fiuzat, Mona, Becker, Richard, Felker, G. Michael, Metra, Marco, and O'Connor, Christopher M.
Subjects: FIBRINOLYTIC agents, THROMBOEMBOLISM, HEART failure patients, ANTICOAGULANTS, PLATELET aggregation inhibitors
Abstract: The article talks about antithrombotic therapy with patients with heart failure (HF). The risk of increased venous thromboembolism (VTE) is present in patients that have suffered HF. The role of antithrombotic therapy remains unclear despite increased risk of VTE. There is difficulty in making decisions when it comes to administering antithrombotic therapy to patients with HF. Alternative anticoagulants and anti-platelet agents such as direct thrombin inhibitors, factor Xa inhibitors, and thrombin receptor antagonists are being developed and reassessed.
Published: 2011
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