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Start Over Author "Patel, Neil N." Journal circulation: cardiovascular genetics
2 results on '"Patel, Neil N."'

2. GATA-Binding Factor 6 Contributes to Atrioventricular Node Development and Function.

Author

Fang Liu, Min Min Lu, Patel, Neil N., Schillinger, Kurt J., Tao Wang, and Patel, Vickas V.

Subjects
GATA proteins, HEART conduction system, ATRIOVENTRICULAR node, HIS bundle, POSTNATAL care, CELL cycle
Abstract

The article discusses a research which examines the role of GATA-binding factor 6 (GATA6) in cardiac conduction system (CCS) and embryonic heart. It indicates that myocardial-specific deletion of the carboxyl zinc-finger of Gata6 alters the CCS in postnatal life and reduces cell-cycle exit of TBX3+ myocytes in the developing atrioventricular bundle. It reveals that GATA6 contributes to the atrioventricular node's development and postnatal function.

Published
2015
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