1. Levofloxacin Pharmacokinetics in Adult Cystic Fibrosis.
- Author
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Lee, Carlton K. K., Boyle, Michael P., Diener-West, Marie, Brass-Ernst, Lois, Noschese, Michelle, and Zeitlin, Pamela L.
- Subjects
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ANTIBIOTICS , *CYSTIC fibrosis , *PSEUDOMONAS aeruginosa , *LUNG diseases , *PHARMACOKINETICS , *BODY weight - Abstract
The article presents a study which aims to examine the effectiveness of Levofloxacin in treating cystic fibrosis (CF) patients. Numerous data revealed that CF levofloxacin pharmacokinetics corrected for body weight are similar to non-CF but the standard levofloxacin dosing is unlikely to produce maximum therapeutic effectiveness. Thus, further levofloxacin CF studies are essential to assess its phlegm concentrations for coping Pseudomonas Aeruginosa pulmonary infections.
- Published
- 2007
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