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Levofloxacin Pharmacokinetics in Adult Cystic Fibrosis.

Authors :
Lee, Carlton K. K.
Boyle, Michael P.
Diener-West, Marie
Brass-Ernst, Lois
Noschese, Michelle
Zeitlin, Pamela L.
Source :
CHEST. Mar2007, Vol. 131 Issue 3, p796-802. 7p. 3 Charts, 2 Graphs.
Publication Year :
2007

Abstract

The article presents a study which aims to examine the effectiveness of Levofloxacin in treating cystic fibrosis (CF) patients. Numerous data revealed that CF levofloxacin pharmacokinetics corrected for body weight are similar to non-CF but the standard levofloxacin dosing is unlikely to produce maximum therapeutic effectiveness. Thus, further levofloxacin CF studies are essential to assess its phlegm concentrations for coping Pseudomonas Aeruginosa pulmonary infections.

Details

Language :
English
ISSN :
00123692
Volume :
131
Issue :
3
Database :
Academic Search Index
Journal :
CHEST
Publication Type :
Academic Journal
Accession number :
24511471
Full Text :
https://doi.org/10.1378/chest.06-1524