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Keywords: biosensors; glutathione; heterogeneous structures; metal-organic frameworks; singlet oxygen EN biosensors glutathione heterogeneous structures metal-organic frameworks singlet oxygen 1 5 5 06/06/22 20220601 NES 220601 A core-shell heterogeneous metal-organic framework (MOF) hybrid is sequentially designed by a photosensitized porous coordination network (PCN)-typed MOF as core and Cu SP 2+ sp -centered zeolitic imidazolate framework (ZIF-67) as shell encapsulating cyanine 3-labelled siRNA. Taking together, these results manifested that intracellular GSH could be consumed to trigger PSZ for the PDT-assisted gene synergistic therapy, achieving the comprehensive cell apoptosis via the synergistic GSH-controlled siRNA release, GSH depletion and promoted SP 1 sp O SB 2 sb generation. In addition to the GSH-responsive siRNA release and fluorescence enhancement, the GSH unlocking effect on SP 1 sp O SB 2 sb production was also explored for purpose of controllable PDT by monitoring the enhanced fluorescence at 525 nm of a SP 1 sp O SB 2 sb indicator named singlet oxygen sensor green (SOSG). Moreover, the siRNA-encapsulated ZIF-67 (S-ZIF67) without PCN core realized the cellular GSH scavenging similarly, whereas the bare PCN revealed no obvious effect on GSH depletion. [Extracted from the article]

Mg-Li hybrid batteries have attracted wide interest in recent years because of their potential safety as well as their cost benefit and high volumetric capacity. However, slow kinetic properties strongly hinder their commercial application. In this study, we have prepared spinel LiCrTiO4 by a solid-state reaction and have conducted a comprehensive study aimed at improving the performance of Mg-Li hybrid batteries by optimizing the dual-salt electrolyte. LiCrTiO4 has been found to show reversible discharge/charge capacities of 178 and 169 mA h g−1 in electrolytes of 1 m LiCl and 0.3 m APC (all-phenyl-complex), respectively. When the concentration of APC was increased to 0.4 m, LiCrTiO4 showed a high capacity retention of 95 % after 30 cycles. In addition, no phase transition could be observed for an LiCrTiO4 electrode in a dual-salt system, suggesting high electrochemical reversibility. Ex situ EDX and SEM studies have indicated that only Li+ ions are inserted into the cathode side, while Mg2+ ions are reversibly deposited on the surface of Mg metal without dendrite-like growth, indicative of good safety of the Mg-Li hybrid batteries. [ABSTRACT FROM AUTHOR]