1. Easix Indices Predict CRS and Overall Survival in Adult CAR-T Cell Recipients
- Author
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Gavriilaki, Eleni, Tzannou, Ifigeneia, Vardi, Anna, Tsonis, Ioannis, Liga, Maria, Girkas, Konstantinos, Ximeri, Maria, Bousiou, Zoi, Bouzani, Maria, Sagiadinou, Eleutheria, Dolgyras, Panagiotis, Bampali, Vasiliki, Mallouri, Despina, Tzenou, Tatiana, Batsis, Ioannis, Spyridis, Nikolaos, Sotiropoulos, Damianos, Anagnostopoulos, Achilles, Karakasis, Dimitrios, Papadaki, Eleni, Tsirigotis, Panagiotis, Spyridonidis, Alexandros, Angelopoulou, Maria, Sakellari, Ioanna, and Baltadakis, Ioannis
- Abstract
Background:Immunotherapy with Chimeric Antigen Receptor T cells (CAR-Τ) is worldwide commercially available for refractory B cell malignancies, with continuously expanding indications.Given that cytokine release syndrome (CRS) and neurotoxicity (ICANS) are encountered in many CAR-T recipients both in trials and real-world setting, novel predictive and prognostic markers are highly needed.
- Published
- 2023
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