Back to Search Start Over

Easix Indices Predict CRS and Overall Survival in Adult CAR-T Cell Recipients

Authors :
Gavriilaki, Eleni
Tzannou, Ifigeneia
Vardi, Anna
Tsonis, Ioannis
Liga, Maria
Girkas, Konstantinos
Ximeri, Maria
Bousiou, Zoi
Bouzani, Maria
Sagiadinou, Eleutheria
Dolgyras, Panagiotis
Bampali, Vasiliki
Mallouri, Despina
Tzenou, Tatiana
Batsis, Ioannis
Spyridis, Nikolaos
Sotiropoulos, Damianos
Anagnostopoulos, Achilles
Karakasis, Dimitrios
Papadaki, Eleni
Tsirigotis, Panagiotis
Spyridonidis, Alexandros
Angelopoulou, Maria
Sakellari, Ioanna
Baltadakis, Ioannis
Source :
Blood; November 2023, Vol. 142 Issue: 1, Number 1 Supplement 1 p6905-6905, 1p
Publication Year :
2023

Abstract

Background:Immunotherapy with Chimeric Antigen Receptor T cells (CAR-Τ) is worldwide commercially available for refractory B cell malignancies, with continuously expanding indications.Given that cytokine release syndrome (CRS) and neurotoxicity (ICANS) are encountered in many CAR-T recipients both in trials and real-world setting, novel predictive and prognostic markers are highly needed.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
142
Issue :
1, Number 1 Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs64591123
Full Text :
https://doi.org/10.1182/blood-2023-179506