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Start Over Author "Lim, Amareth" Journal biochemistry
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1. D18G transthyretin is monomeric, aggregation prone, and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis?

Author

Hammarstrom, Per, Sekijima, Yoshiki, White, Joleen T., Wiseman, R. Luke, Lim, Amareth, Costello, Catherine E., Altland, Klaus, Garzuly, Ferenc, Budka, Herbert, and Kelly, Jeffery W.

Subjects
Monomers -- Physiological aspects, Monomers -- Genetic aspects, Amyloidosis -- Causes of, Cell membranes -- Physiological aspects, Cell membranes -- Genetic aspects, Central nervous system -- Physiological aspects, Gene mutations -- Physiological aspects, Biophysics -- Research, Biological sciences, Chemistry
Abstract

Research has been conducted on D18G transthyretin. The authors describe the biophysical properties of this transthyretin, and report that it is an unstable monomeric protein.

Published
2003

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