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D18G transthyretin is monomeric, aggregation prone, and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis?
- Source :
- Biochemistry. June 10, 2003, Vol. 42 Issue 22, 6656-6663
- Publication Year :
- 2003
-
Abstract
- Research has been conducted on D18G transthyretin. The authors describe the biophysical properties of this transthyretin, and report that it is an unstable monomeric protein.
- Subjects :
- Monomers -- Physiological aspects
Monomers -- Genetic aspects
Amyloidosis -- Causes of
Cell membranes -- Physiological aspects
Cell membranes -- Genetic aspects
Central nervous system -- Physiological aspects
Gene mutations -- Physiological aspects
Biophysics -- Research
Biological sciences
Chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 00062960
- Volume :
- 42
- Issue :
- 22
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.104550194