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597 results on '"Conformational analysis"'

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1. Probing the Impact of Local Structural Dynamics of Conformational Epitopes on Antibody Recognition.

2. Molecular Crowding Affects the Conformational Fluctuations, Peroxidase Activity, and Folding Landscape of Yeast Cytochrome c.

3. Conformational Dynamics of the Human Islet Amyloid Polypeptide in a Membrane Environment: Toward the Aggregation Prone Form.

4. Conformational Flexibility Enables the Function of a BECN1 Region Essential for Starvation-Mediated Autophagy.

5. Ligand-Dependent Conformational Dynamics of Dihydrofolate Reductase.

6. Conformational Disorganization within the Active Site of a Recently Evolved Organophosphate Hydrolase Limits Its Catalytic Efficiency.

7. Concurrent Increases and Decreases in Local Stability and Conformational Heterogeneity in Cu, Zn Superoxide Dismutase Variants Revealed by Temperature-Dependence of Amide Chemical Shifts.

8. The Dynamic Landscape of the Full-Length HIV-1 Transactivator of Transcription.

9. Coordinated Action of Two Double-Stranded RNA Binding Motifs and an RGG Motif Enables Nuclear Factor 90 To Flexibly Target Different RNA Substrates.

10. Effect of Fc-Glycan Structure on the Conformational Stability of IgG Revealed by Hydrogen/Deuterium Exchange and Limited Proteolysis.

11. Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase.

12. Metal Ion Capture Mechanism of a Copper Metallochaperone.

13. The Pathogenic Mutation T182A Converts the Prion Protein into a Molten Globule-like Conformation Whose Misfolding to Oligomers but Not to Fibrils Is Drastically Accelerated.

14. Alternative Conformations of Cytochrome c: Structure, Function, and Detection.

15. Dynamic and Static Water Molecules Complement the TN16 Conformational Heterogeneity inside the Tubulin Cavity.

16. Conformations of Human Telomeric G-Quadruplex Studied Using a Nucleotide-Independent Nitroxide Label.

17. Crystal Structure of Recoverin with Calcium Ions Bound to Both Functional EF Hands.

18. Origin of the Enigmatic Stepwise Tight-Binding Inhibition of Cyclooxygenase-1.

19. Cholesterol-Dependent Conformational Exchange of the C-Terminal Domain of the Influenza A M2 Protein.

20. Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.

21. Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site.

22. Site-Selective Monitoring of the Interaction of the SRA Domain of UHRF1 with Target DNA Sequences Labeled with 2-Aminopurine.

23. A Natural Interruption Displays Higher Global Stability and Local Conformational Flexibility than a Similar Gly Mutation Sequence in Collagen Mimic Peptides.

24. Conformational Changes of the Antibacterial Peptide ATP Binding Cassette Transporter McjD Revealed by Molecular Dynamics Simulations.

25. Interfacial Activation of Candida antarctica Lipase B: Combined Evidence from Experiment and Simulation.

26. Methyl Relaxation Measurements Reveal Patterns of Fast Dynamics in a Viral RNA-Directed RNA Polymerase.

27. An Engineered SS Bridge Blocks the Conformational Change Required for the Nuclease Activity of Bfil.

28. Concerted Protein and Nucleic Acid Conformational Changes Observed Prior to Nucleotide Incorporation in a Bacterial RNA Polymerase: Raman Crystallographic Evidence.

29. O2 and Water Migration Pathways between the Solvent and Heme Pockets of Hemoglobin with Open and Closed Conformations of the Distal HisE7.

30. Investigating the in Vitro Thermal Stability and Conformational Flexibility of Estrogen Receptors as Potential Key Factors of Their in Vivo Activity.

31. The Lys-Specific Molecular Tweezer, CLR01, Modulates Aggregation of the Mutant p53 DNA Binding Domain and Inhibits Its Toxicity.

32. ATP Acyl Phosphate Reactivity Reveals Native Conformations of Hsp90 Paralogs and Inhibitor Target Engagement.

33. The Conformation of a Catalytic Loop Is Central to GTPase Activity on the Ribosome.

34. Distal Regulation of Heme Binding of Heme Oxygenase-1 Mediated by Conformational Fluctuations.

35. Axial Hydrogen at C7 Position and Bumpy Tetracyclic Core Markedly Reduce Sterol's Affinity to Amphotericin B in Membrane.

36. An Experimentally Robust Model of Monomeric Apolipoprotein A-l Created from a Chimera of Two X-ray Structures and Molecular Dynamics Simulations.

37. Modifying Caspase-3 Activity by Altering Allosteric Networks.

38. Structural Insight into the MC4R Conformational Changes via Different Agonist-Mediated Receptor Signaling.

39. Conformational Selection and Functional Dynamics of Calmodulin: A 19F Nuclear Magnetic Resonance Study.

40. Recent Insight into the Kinetic Mechanisms and Conformational Dynamics of Y-Family DNA Polymerases.

41. Conformational Activation of Poly(ADP-ribose) Polymerase-1 upon DNA Binding Revealed by Small-Angle X-ray Scattering.

42. Conformational Dynamics of a Y-Family DNA Polymerase during Substrate Binding and Catalysis As Revealed by Interdomain Förster Resonance Energy Transfer.

43. The Thermal Stability of Recoverin Depends on Calcium Binding and Its Myristoyl Moiety As Revealed by Infrared Spectroscopy.

44. Conformational dynamics of DNA polymerase probed with a novel fluorescent DNA base analogue

45. Amide exchange shows calcium-induced conformational changes are transmitted to the dimer interface of S100

46. S-nitrosylation of platelet [alpha.sub.IIb][beta.sub.3] as revealed by Raman spectroscopy

47. Isomers of human [alpha]-synuclein stabilized by disulfide bonds exhibit distinct structural and aggregative properties

48. A new paradigm for DNA polymerase specificity

49. The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol

50. Substrates induce conformational changes in human anion exchanger 1 (hAE1) as observed by fluorescence resonance energy transfer

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