1. Production of 117mSn with high specific activity by cyclotron
- Author
-
Zoltan Szucs, Grigory K. Vostokin, V.N. Shvetsov, G. Ya. Starodub, S. N. Dmitriev, O. D. Maslov, M. V. Gustova, Jan Rijn Zeevaart, and D. Jansen
- Subjects
Radionuclide ,Radiation ,Cyclotron ,Radiochemistry ,chemistry.chemical_element ,law.invention ,chemistry ,High specific activity ,law ,Yield (chemistry) ,Radionuclide therapy ,Fluorine ,Specific activity ,Irradiation ,Nuclear chemistry - Abstract
A method to produce (117m)Sn radionuclide using accelerator production route is described. A new method is proposed to separate the (117m)Sn. Specific activities and thick target yield for (116)Cd(α,3n)(117m)Sn reaction at E(α)=35MeV bombarding energy were determined. The estimated production yield of (117m)Sn was 37.5kBq/μAh for 13.16 mg/cm(2) natural cadmium-oxide target and 410 kBq/μAh for 11.07 mg/cm(2) highly enriched (95%) (116)CdO target. The method developed for separation of (117m)Sn from Cd using anion-exchange resin (Dowex -1×8, fluorine form, 400 mesh) can achieve 98% radiochemical yield of (117m)Sn with more than 99% radionuclidic purity. The estimated specific activity is 2.4 GBq/mg that can be reached with the used irradiation conditions.
- Published
- 2011