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Start Over Author "Qilin Gao" Journal applied and environmental microbiology
1 results on '"Qilin Gao"'

1. Improved 2α-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design

Author

Qilin Gao, Bingbing Ma, Qianwen Wang, Hao Zhang, Shinya Fushinobu, Jian Yang, Susu Lin, Keke Sun, Bing-Nan Han, and Lian-Hua Xu

Subjects
Ecology, Applied Microbiology and Biotechnology, Food Science, Biotechnology
Abstract

Hydroxylated derivatives of steroids play essential roles in medicine. Cytochrome P450 enzymes selectively hydroxylate methyne groups on steroids, which can dramatically change their polarity, biological activity and toxicity.

Published
2023
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