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Your search keyword '"Escobar, H."' showing total 11 results
Start Over Author "Escobar, H." Journal animal genetics
11 results on '"Escobar, H."'

3. The canine NRAS gene maps to CFA 17

Author

Richter, A., Escobar, H. Murua, Günther, K., Meyer, B., Winkler, S., Dolf, G., Schelling, C., Nolte, I., and Bullerdiek, J.

Published
2004

9. BRIEF NOTES DNA sequence, polymorphism, and mapping of luteinizing hormone receptor fragment ( LHCGR) gene in Great Dane dogs.

Author

Santos, S. E. C., Escobar, H. Murua, Sider, L. H., Winkler, S., Aoki, S. M., Milazzotto, M. P., Campagnari, F., Vannucchi, C. I., Bullerdiek, J., Nolte, I., and Garcia, J. F.

Subjects
*NUCLEOTIDE sequence, *GENETIC polymorphisms, *GENE mapping, *LUTEINIZING hormone, *HORMONE receptors, *GREAT Dane
Abstract

This article cites a study on DNA sequence, polymorphism and mapping of luteinizing hormone receptor fragment (LHCGR) gene in Great Dane dogs. Exon 11 of the canine LHCGR gene was polymerase chain reaction amplified and sequenced. Primers were designed based upon previous bovine LHCGR gene sequence. Activating and inactivating mutations have been described in the same receptor in humans. Genomic DNA was isolated from Great Dane dog's peripheral blood leucocytes using phenol/chloroform purification based protocols.

Published
2004
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10. Molecular characterization and mapping of the caninecyclin D1(CCND1) gene.

Author

Meyer, B., Escobar, H. Murua, Winkler, S., Dolf, G., Schelling, C., Bullerdiek, J., and Nolte, I.

Subjects
*GENE mapping, *CYCLINS, *ADENOCARCINOMA, *IMMUNOHISTOCHEMISTRY, *NUCLEOTIDE sequence, *GENETIC disorders, *GENE expression, *DOGS
Abstract

The article discusses molecular characterization and mapping of the canine cyclin D1 (CCND1) gene. During the last decade the dog has gained in importance as a model organism for the investigation of mechanisms underlying human genetic disease, including cancer. Immunohistochemical analyses of cyclin D1 expression in canine mammary tumours using a polyclonal antibody against human cyclin D1 revealed contradictory data. A researcher found cyclin D1 expression in only two adenocarcinomas of 75 mammary lesions tested. Mapping and sequencing of the canine CCND1 gene and corresponding protein could help to elucidate the role of cyclin D1 in dogs and its usefulness as model organism concerning this matter.

Published
2004
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11. The protein kinase B, gamma (AKT3) gene maps to canine chromosome 7.

Author

Murua Escobar H, Meyer J, Winkler S, Schelling C, Dolf G, Nolte I, and Bullerdiek J

Subjects
Animals, In Situ Hybridization, Fluorescence, Proto-Oncogene Proteins c-akt, Chromosome Mapping, Chromosomes, Mammalian genetics, Dogs genetics, Protein Serine-Threonine Kinases genetics, Proto-Oncogene Proteins genetics
Published
2004
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