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Deals with a study which used decorin to antagonize exogenous tumor growth factor (TGF)-beta-mediated inhibition of lung morphogenesis and cytodifferentiation in a model of embryonic mouse lung morphogenesis ex vivo. Effects of decorin on the TGF-beta-mediated inhibition of embryonic lung development; How intratracheal microinjection of adenovirus carrying human decorin cDNA (AdDcn) prevents TGF-beta-mediated inhibition of embryonic lung branching.

Presents information on a study which examined the molecular embryology of the lung. Genetics of tracheal branching morphogenesis in Drosophila; Pattern formation in the anterior foregut and the morphogenetic function of NKX2.1, a thyroid transcription factor-1; How transcription factors interact in regulatory networks to determine lung epithelial cell fate; Integration of signaling systems in lung morphogenesis.

Investigates the possible regulation of matrix Gla protein by exogenous transforming growth factor-beta (TGF-beta1) during lung development. Embryonic lung culture and TGF-beta1 treatment; mRNA measurement by competitive polymerase chain reaction.