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Adenovirus-mediated decorin gene transfer prevents TGF-beta-induced inhibition of lung...

Authors :
Zhao, Jingsong
Sime, Patricia J.
Source :
American Journal of Physiology: Lung Cellular & Molecular Physiology. Aug99, Vol. 21 Issue 2, pL412. 11p. 1 Color Photograph, 1 Black and White Photograph, 7 Graphs.
Publication Year :
1999

Abstract

Deals with a study which used decorin to antagonize exogenous tumor growth factor (TGF)-beta-mediated inhibition of lung morphogenesis and cytodifferentiation in a model of embryonic mouse lung morphogenesis ex vivo. Effects of decorin on the TGF-beta-mediated inhibition of embryonic lung development; How intratracheal microinjection of adenovirus carrying human decorin cDNA (AdDcn) prevents TGF-beta-mediated inhibition of embryonic lung branching.

Details

Language :
English
ISSN :
10400605
Volume :
21
Issue :
2
Database :
Academic Search Index
Journal :
American Journal of Physiology: Lung Cellular & Molecular Physiology
Publication Type :
Academic Journal
Accession number :
2173863
Full Text :
https://doi.org/10.1152/ajplung.1999.277.2.l412