Search

Your search keyword '"Rotzschke, Olaf"' showing total 6 results
Start Over Author "Rotzschke, Olaf" Journal allergy
6 results on '"Rotzschke, Olaf"'

1. Eosinophilic allergic rhinitis is strongly associated with the CD45RBlo subset of CD161+ Th2 cells that secretes IL‐2, IL‐3, IL‐4, IL‐5, IL‐9, and IL‐13

Author

Lee, Wendy W. L., primary, Puan, Kia Joo, additional, Lee, Bernett, additional, Chua, Celine, additional, Koh, Ser Mei, additional, Yusof, Nurhashikin, additional, Tan, Kim Peng, additional, Luis, Boris San, additional, Ong, Jocelyn, additional, Merid, Simon Kebede, additional, Ang, Rachel, additional, Chan, Xue Ying, additional, Hui, Low Jing, additional, Terenzani, Elisa, additional, Lum, Josephine, additional, Foo, Shihui, additional, Zolezzi, Francesca, additional, Yan, Annabelle Tay Sok, additional, Melen, Erik, additional, Yi, Soh Jian, additional, Rotzschke, Olaf, additional, and Andiappan, Anand Kumar, additional

Published
2023
Full Text
View/download PDF

3. Neutrophilic inflammation and epithelial barrier disruption in nasal polyps characterize non‐steroidal anti‐inflammatory drug exacerbated respiratory disease

Author

Andiappan, Anand Kumar, primary, Asad, Mohammad, additional, Chua, Celine, additional, Sehanobish, Esha, additional, Ren, Zhen, additional, Chan, Xue Ying, additional, Lum, Josephine, additional, Ang, Nicholas, additional, Duan, Kaibo, additional, Gersten, Adam, additional, Abuzeid, Waleed M., additional, Akbar, Nadeem, additional, Gibber, Marc, additional, Howland, Shanshan, additional, Lee, Bernett, additional, Rotzschke, Olaf, additional, Porcelli, Steven A., additional, and Jerschow, Elina, additional

Published
2021
Full Text
View/download PDF

4. Functional CTLA‐4 variants associate to both allergic asthma and rhinitis potentially by modulating naïve regulatory T cells.

Author

Andiappan, Anand Kumar, Puan, Kia Joo, Sio, Yang Yie, Ally, Fauziah, Lee, Bernett, Matta, Sri Anusha, Yusof, Nurhashikin, Larbi, Anis, Wang, De Yun, Chew, Fook Tim, and Rotzschke, Olaf

Subjects
REGULATORY T cells, ALLERGIC rhinitis, CYTOTOXIC T lymphocyte-associated molecule-4, ATOPY, MONONUCLEAR leukocytes, URTICARIA
Abstract

CTLA-4 polymorphisms in allergy and asthma and the TH1/ TH2 paradigm. Functional CTLA-4 variants associate to both allergic asthma and rhinitis potentially by modulating naïve regulatory T cells A genome-wide linkage study previously indicated the chromosome 2q region containing the cytotoxic T-lymphocyte protein 4 ( I CTLA-4 i ) gene might be a candidate asthma locus.1 However, prior reports of associations between I CTLA-4 i genetic variants and asthma are conflicting and inconclusive.2-4 This study aimed to determine the role of I CTLA-4 i single nucleotide polymorphisms (SNPs) on allergy risk by carrying out genetic association and functional analyses. [Extracted from the article]

Published
2022
Full Text
View/download PDF

5. Neutrophilic inflammation and epithelial barrier disruption in nasal polyps characterize non‐steroidal anti‐inflammatory drug exacerbated respiratory disease.

Author

Andiappan, Anand Kumar, Asad, Mohammad, Chua, Celine, Sehanobish, Esha, Ren, Zhen, Chan, Xue Ying, Lum, Josephine, Ang, Nicholas, Duan, Kaibo, Gersten, Adam, Abuzeid, Waleed M., Akbar, Nadeem, Gibber, Marc, Howland, Shanshan, Lee, Bernett, Rotzschke, Olaf, Porcelli, Steven A., and Jerschow, Elina

Subjects
NASAL polyps, RESPIRATORY diseases, ANTI-inflammatory agents, RESPIRATORY agents, INFLAMMATION, IMMUNOGLOBULIN E
Abstract

Conversely, tissue neutrophil association with LM scores in N-ERD patients suggests that neutrophils contribute to the severity of the polyp burden in N-ERD. Neutrophilic inflammation and epithelial barrier disruption in nasal polyps characterize non-steroidal anti-inflammatory drug exacerbated respiratory disease Neutrophil counts were higher in the nasal polyp tissues of N-ERD patients (8.5 cells per hpf (IQR 3-25) vs. 2.5 cells (IQR 2-5) in non-N-ERD ( I p i = .026, Figure 1B). [Extracted from the article]

Published
2022
Full Text
View/download PDF

6. Eosinophilic allergic rhinitis is strongly associated with the CD45RB lo subset of CD161 + Th2 cells that secretes IL-2, IL-3, IL-4, IL-5, IL-9, and IL-13.

Author

Lee WWL, Puan KJ, Lee B, Chua C, Koh SM, Yusof N, Tan KP, Luis BS, Ong J, Merid SK, Ang R, Chan XY, Hui LJ, Terenzani E, Lum J, Foo S, Zolezzi F, Yan ATS, Melen E, Yi SJ, Rotzschke O, and Andiappan AK

Subjects
Humans, Cytokines, Interleukin-13, Interleukin-2, Interleukin-3, Interleukin-4, Interleukin-5, Interleukin-9 genetics, Th1 Cells, Th2 Cells, NK Cell Lectin-Like Receptor Subfamily B, Rhinitis, Allergic, Leukocyte Common Antigens
Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results