Neutrophilic inflammation and epithelial barrier disruption in nasal polyps characterize non‐steroidal anti‐inflammatory drug exacerbated respiratory disease.

Conversely, tissue neutrophil association with LM scores in N-ERD patients suggests that neutrophils contribute to the severity of the polyp burden in N-ERD. Neutrophilic inflammation and epithelial barrier disruption in nasal polyps characterize non-steroidal anti-inflammatory drug exacerbated respiratory disease Neutrophil counts were higher in the nasal polyp tissues of N-ERD patients (8.5 cells per hpf (IQR 3-25) vs. 2.5 cells (IQR 2-5) in non-N-ERD ( I p i = .026, Figure 1B). [Extracted from the article]